1987
Parotid Gland Salivary Secretion in Tourette's Syndrome and Attention Deficit Disorder: A Model System for the Study of Neurochemical Regulation
COHEN D, ORT S, CARUSO K, ANDERSON G, HUNT R, SHAYWITZ B, KREMENITZER M, LECKMAN J. Parotid Gland Salivary Secretion in Tourette's Syndrome and Attention Deficit Disorder: A Model System for the Study of Neurochemical Regulation. Journal Of The American Academy Of Child & Adolescent Psychiatry 1987, 26: 65-68. PMID: 3034852, DOI: 10.1097/00004583-198701000-00013.Peer-Reviewed Original ResearchConceptsAttention deficit disorderTourette syndromeSalivary amylase concentrationTS patientsAmylase concentrationSalivary secretionNeurochemical regulationReceptor functioningTreatment of TSDeficit disorderSalivary amylase secretionParotid gland secretionSingle dosesSalivary volumeClonidinePatientsAmylase secretionSyndromeADD patientsSalivary measuresSecretionTotal amylaseSalivary amylaseDisordersChildren
1983
Acute and Chronic CLonidine Treatment in Tourette's Syndrome A Preliminary Report on Clinical Response and Effect on Plasma and Urinary Catecholamine Metabolites, Growth Hormone, and Blood Pressure
LECKMAN J, DETLOR J, HARCHERIK D, YOUNG J, ANDERSON G, SHAYWITZ B, COHEN D. Acute and Chronic CLonidine Treatment in Tourette's Syndrome A Preliminary Report on Clinical Response and Effect on Plasma and Urinary Catecholamine Metabolites, Growth Hormone, and Blood Pressure. Journal Of The American Academy Of Child & Adolescent Psychiatry 1983, 22: 433-440. PMID: 6579101, DOI: 10.1016/s0002-7138(09)61504-1.Peer-Reviewed Original ResearchConceptsChronic clonidine treatmentClonidine treatmentTourette syndromeHomovanillic acidHuman growth hormoneClinical responseBlood pressureGrowth hormoneΑ2-adrenergic receptor agonistTreatment of TSUrinary catecholamine metabolitesClinical response dataChronic neuropsychiatric disorderPlacebo-controlled conditionsA Preliminary ReportClonidine therapyOral clonidineNoradrenergic receptorsSingle doseUnknown etiologyFunctional statusReceptor agonistClinical trialsDopaminergic systemTS patients