2000
Pharmacogenetics: Promise and Potential in Child and Adolescent Psychiatry
Anderson G, Cook E. Pharmacogenetics: Promise and Potential in Child and Adolescent Psychiatry. Child And Adolescent Psychiatric Clinics Of North America 2000, 9: 23-42. PMID: 10674189, DOI: 10.1016/s1056-4993(18)30134-2.Peer-Reviewed Original ResearchImaging extrastriatal dopamine D2 receptor occupancy by endogenous dopamine in healthy humans
Fujita M, Verhoeff N, Varrone A, Zoghbi S, Baldwin R, Jatlow P, Anderson G, Seibyl J, Innis R. Imaging extrastriatal dopamine D2 receptor occupancy by endogenous dopamine in healthy humans. European Journal Of Pharmacology 2000, 387: 179-188. PMID: 10650158, DOI: 10.1016/s0014-2999(99)00817-1.Peer-Reviewed Original ResearchConceptsAcute dopamine depletionDopamine depletionEndogenous dopamineAlpha-methylTemporal cortexExtrastriatal dopamine D2 receptor occupancyDopamine D2 receptor occupancyD2 receptor occupancySynaptic dopamine concentrationsSingle photon emissionNegative Symptom ScalePara-tyrosineExtrastriatal regionsOral administrationHealthy humansSymptom ScaleReceptor occupancyDopamine concentrationsDysphoric moodDopaminePhoton emissionHigh-affinity ligandsCortexVivo measurementsThalamus
1987
Amphetamine reverses learning deficits in 6‐hydroxydopamine‐treated rat pups
Wool R, Weldon D, Shaywitz B, Anderson G, Cohen D, Teicher M. Amphetamine reverses learning deficits in 6‐hydroxydopamine‐treated rat pups. Developmental Psychobiology 1987, 20: 219-232. PMID: 3108057, DOI: 10.1002/dev.420200210.Peer-Reviewed Original ResearchConceptsBrain dopamineRat pupsCombination of desmethylimipramineD-amphetamine sulfateVehicle control solutionDays of ageTime of injectionAmphetamine treatmentControl animalsYoung ratsDesmethylimipramineLemon odorPupsDopamineOlfactory sensitivityAnimalsNovel odorOlfactory preferencesStimuliDaysExperiment IVRatsSensitization
1985
Cerebrospinal fluid (CSF) and brain monoamine metabolites in the developing rat pup
Shaywitz B, Anderson G, Cohen D. Cerebrospinal fluid (CSF) and brain monoamine metabolites in the developing rat pup. Brain Research 1985, 17: 225-232. DOI: 10.1016/0165-3806(85)90146-4.Peer-Reviewed Original Research
1983
Dopaminergic but not noradrenergic mediation of hyperactivity and performance deficits in the developing rat pup
Shaywitz B, Teicher M, Cohen D, Anderson G, Young J, Levitt P. Dopaminergic but not noradrenergic mediation of hyperactivity and performance deficits in the developing rat pup. Psychopharmacology 1983, 82: 73-77. PMID: 6420833, DOI: 10.1007/bf00426384.Peer-Reviewed Original ResearchConceptsRat pupsDays of ageMotor activityBehavioral arousalPostsynaptic dopaminergic mechanismsReduction of norepinephrineReduction of dopamineGeneral motor activityMesolimbic dopaminergic pathwayDopaminergic mechanismsBrain dopaminePreferential reductionEscape latencyNoradrenergic mediationNorepinephrinePostnatal lifeWeek 3PupsSuch treatmentDopamineT-mazeShuttle boxAgeDesmethylimipraminePerformance deficits
1982
Effects of apomorphine on appetitive conditioning in 6-hydroxydopamine treated rat pups
Weldon D, Wool R, Teicher M, Shaywitz B, Cohen D, Anderson G. Effects of apomorphine on appetitive conditioning in 6-hydroxydopamine treated rat pups. Pharmacology Biochemistry And Behavior 1982, 17: 1281-1284. PMID: 6819587, DOI: 10.1016/0091-3057(82)90134-4.Peer-Reviewed Original ResearchConceptsApomorphine administrationRat pupsCombination of desmethylimipramineEffects of apomorphinePostnatal day 5Brain dopamineControl injectionsDrug treatmentNormal pupsIsotonic salineDay 5Appetitive responsesPupsImpaired performanceNext dayDesmethylimipramineApomorphineBaby formulaAnise odorAppetitive conditioningAdministrationSalineDopamineNovel odorAnimals