1987
Amphetamine reverses learning deficits in 6‐hydroxydopamine‐treated rat pups
Wool R, Weldon D, Shaywitz B, Anderson G, Cohen D, Teicher M. Amphetamine reverses learning deficits in 6‐hydroxydopamine‐treated rat pups. Developmental Psychobiology 1987, 20: 219-232. PMID: 3108057, DOI: 10.1002/dev.420200210.Peer-Reviewed Original ResearchConceptsBrain dopamineRat pupsCombination of desmethylimipramineD-amphetamine sulfateVehicle control solutionDays of ageTime of injectionAmphetamine treatmentControl animalsYoung ratsDesmethylimipramineLemon odorPupsDopamineOlfactory sensitivityAnimalsNovel odorOlfactory preferencesStimuliDaysExperiment IVRatsSensitization
1983
Dopaminergic but not noradrenergic mediation of hyperactivity and performance deficits in the developing rat pup
Shaywitz B, Teicher M, Cohen D, Anderson G, Young J, Levitt P. Dopaminergic but not noradrenergic mediation of hyperactivity and performance deficits in the developing rat pup. Psychopharmacology 1983, 82: 73-77. PMID: 6420833, DOI: 10.1007/bf00426384.Peer-Reviewed Original ResearchConceptsRat pupsDays of ageMotor activityBehavioral arousalPostsynaptic dopaminergic mechanismsReduction of norepinephrineReduction of dopamineGeneral motor activityMesolimbic dopaminergic pathwayDopaminergic mechanismsBrain dopaminePreferential reductionEscape latencyNoradrenergic mediationNorepinephrinePostnatal lifeWeek 3PupsSuch treatmentDopamineT-mazeShuttle boxAgeDesmethylimipraminePerformance deficits
1982
Effects of apomorphine on appetitive conditioning in 6-hydroxydopamine treated rat pups
Weldon D, Wool R, Teicher M, Shaywitz B, Cohen D, Anderson G. Effects of apomorphine on appetitive conditioning in 6-hydroxydopamine treated rat pups. Pharmacology Biochemistry And Behavior 1982, 17: 1281-1284. PMID: 6819587, DOI: 10.1016/0091-3057(82)90134-4.Peer-Reviewed Original ResearchConceptsApomorphine administrationRat pupsCombination of desmethylimipramineEffects of apomorphinePostnatal day 5Brain dopamineControl injectionsDrug treatmentNormal pupsIsotonic salineDay 5Appetitive responsesPupsImpaired performanceNext dayDesmethylimipramineApomorphineBaby formulaAnise odorAppetitive conditioningAdministrationSalineDopamineNovel odorAnimals
1981
Effects of bromocriptine in developing rat pups after 6-hydroxydopamine
Shaywitz B, Lipton S, Teicher M, Cohen D, Anderson G, Batter D, Young J. Effects of bromocriptine in developing rat pups after 6-hydroxydopamine. Pharmacology Biochemistry And Behavior 1981, 15: 443-448. PMID: 6794039, DOI: 10.1016/0091-3057(81)90275-6.Peer-Reviewed Original ResearchConceptsVehicle pupsHigh dosesDays of ageRat pupsCombination of desmethylimipramineInhibitory dopaminergic mechanismDoses of bromocriptineEffects of bromocriptineLittle clinical utilityGeneral motor activityAttention deficit disorderHole boxVehicle animalsDenervation supersensitivityDopaminergic mechanismsBrain dopamineClinical syndromeCommon disorderBromocriptineClinical utilityLonger observation periodPharmacological agentsPostnatal lifeMotor activityFirst month