2011
Diffusion Tensor Imaging in Autism Spectrum Disorders: Preliminary Evidence of Abnormal Neural Connectivity
Jou RJ, Jackowski AP, Papademetris X, Rajeevan N, Staib LH, Volkmar FR. Diffusion Tensor Imaging in Autism Spectrum Disorders: Preliminary Evidence of Abnormal Neural Connectivity. Australian & New Zealand Journal Of Psychiatry 2011, 45: 153-162. PMID: 21128874, PMCID: PMC3123660, DOI: 10.3109/00048674.2010.534069.Peer-Reviewed Original Research
2001
Methodological Issues in Designing a Multisite Trial of Risperidone in Children and Adolescents with Autism
Scahill L, McCracken J, McDougle C, Aman M, Arnold L, Tierney E, Cronin P, Davies M, Ghuman J, Gonzalez N, Koenig K, Lindsay R, Martin A, McGough J, Posey D, Swiezy N, Volkmar F, Ritz L, Vitiello B. Methodological Issues in Designing a Multisite Trial of Risperidone in Children and Adolescents with Autism. Journal Of Child And Adolescent Psychopharmacology 2001, 11: 377-388. PMID: 11838820, DOI: 10.1089/104454601317261555.Peer-Reviewed Original ResearchConceptsPlacebo-controlled studyPlacebo-controlled discontinuation studyAutistic disorderSafety of risperidoneStudy of RisperidoneStandard pharmacological treatmentSelf-injurious behaviorDiscontinuation studyPharmacological treatmentClinical trialsInclusion criteriaLong-term effectsSevere tantrumsTrial designClinical relevanceClinical practiceLength of trialRisperidoneMultisite trialStudy designContinuous treatmentTrialsTreatment effectsDisordersMaintenance phaseSpeech and Prosody Characteristics of Adolescents and Adults With High-Functioning Autism and Asperger Syndrome
Shriberg L, Paul R, McSweeny J, Klin A, Cohen D, Volkmar F. Speech and Prosody Characteristics of Adolescents and Adults With High-Functioning Autism and Asperger Syndrome. Journal Of Speech Language And Hearing Research 2001, 44: 1097-1115. PMID: 11708530, DOI: 10.1044/1092-4388(2001/087).Peer-Reviewed Original ResearchConceptsHigh functioning autismPervasive developmental disorderAsperger syndromeDevelopmental disordersMale speakersGroups of speakersAffective aspectsTypical speakersProsody characteristicsSocial sourcesDiscourse constraintsSpeakersAutismSpeechUtterancesMore participantsDistortion errorsAge rangeProsodyDisordersAdolescentsFindingsParticipantsPhrasingAdults
2000
Toward a Developmental Operational Definition of Autism
Gillham J, Carter A, Volkmar F, Sparrow S. Toward a Developmental Operational Definition of Autism. Journal Of Autism And Developmental Disorders 2000, 30: 269-278. PMID: 11039854, DOI: 10.1023/a:1005571115268.Peer-Reviewed Original ResearchConceptsMental ageSocialization scoresChronological ageDevelopmental disordersVineland Adaptive Behavior ScalesLarge normative sampleDaily living skillsAdaptive behavior scoresTraditional diagnostic schemeDiagnosis of autismAdaptive Behavior ScalesAutism groupIntellectual functioningNormative sampleMaladaptive behaviorsChild communicationVineland scoresDevelopmental levelBasis of socializationSerious maladaptive behaviorsLiving skillsStandardized measuresAutismBehavior ScaleAdaptive behaviorThe Children's Social Behavior Questionnaire for Milder Variants of PDD Problems: Evaluation of the Psychometric Characteristics
Luteijn E, Luteijn F, Jackson S, Volkmar F, Minderaa R. The Children's Social Behavior Questionnaire for Milder Variants of PDD Problems: Evaluation of the Psychometric Characteristics. Journal Of Autism And Developmental Disorders 2000, 30: 317-330. PMID: 11039858, DOI: 10.1023/a:1005527300247.Peer-Reviewed Original ResearchConceptsChildren's Social Behavior QuestionnaireSocial Behavior QuestionnaireChild Behavior ChecklistADHD groupAutism Behavior ChecklistPDDNOS groupBehavior ChecklistBehavior QuestionnaireGood psychometric qualitiesSignificant group differencesChild psychiatric disordersAutism groupInsight ScaleInsight problemBehavior problemsPsychometric qualitiesGroup differencesPsychometric characteristicsStereotypical behaviorsHigher scoresLarge sampleRigid behaviorComparison of groupsScale constructionChildrenBrief Report: Interrater Reliability of Clinical Diagnosis and DSM-IV Criteria for Autistic Disorder: Results of the DSM-IV Autism Field Trial
Klin A, Lang J, Cicchetti D, Volkmar F. Brief Report: Interrater Reliability of Clinical Diagnosis and DSM-IV Criteria for Autistic Disorder: Results of the DSM-IV Autism Field Trial. Journal Of Autism And Developmental Disorders 2000, 30: 163-167. PMID: 10832781, DOI: 10.1023/a:1005415823867.Peer-Reviewed Original ResearchVerbal Bias in Recognition of Facial Emotions in Children with Asperger Syndrome
Grossman J, Klin A, Carter A, Volkmar F. Verbal Bias in Recognition of Facial Emotions in Children with Asperger Syndrome. Journal Of Child Psychology And Psychiatry 2000, 41: 369-379. PMID: 10784084, DOI: 10.1111/1469-7610.00621.Peer-Reviewed Original ResearchConceptsFacial emotionsAsperger syndromeFacial expressionsAffective processing taskVerbal mediationSimple emotionsVerbal labelsVerbal IQAsperger groupVerbal biasNonclinical populationsEmotionsCompensatory strategiesProcessing tasksControl childrenChronological ageChildrenQualitative differencesIQAdolescentsBiasWordsTaskControl groupMediationResearch Units on Pediatric Psychopharmacology (Rupp) Autism Network Background and Rationale for an Initial Controlled Study of Risperidone
McDougle C, Scahill L, McCracken J, Aman M, Tierney E, Arnold L, Freeman B, Martin A, McGough J, Cronin P, Posey D, Riddle M, Ritz L, Swiezy N, Vitiello B, Volkmar F, Votolato N, Walson P. Research Units on Pediatric Psychopharmacology (Rupp) Autism Network Background and Rationale for an Initial Controlled Study of Risperidone. Child And Adolescent Psychiatric Clinics Of North America 2000, 9: 201-224. PMID: 10674197, DOI: 10.1016/s1056-4993(18)30142-1.Peer-Reviewed Original ResearchConceptsOpen-label trialDA neuronal systemsSafety of risperidoneStudy of RisperidonePlacebo-controlled studyUse of risperidoneExtrapyramidal side effectsTarget of pharmacotherapyTreatment of childrenImpaired social behaviorLong-term effectivenessPreclinical evidenceReceptor blockadeTypical antipsychoticsControlled StudyFirst drugPathophysiology of autismLower riskShort-term benefitsSide effectsRisperidonePotent effectsSymptoms of autismNeuronal systemsEnhanced efficacy
1999
Practice parameters for the assessment and treatment of children, adolescents, and adults with autism and other pervasive developmental disorders
Volkmar F, Cook E, Pomeroy J, Realmuto G, Tanguay P, Issues T. Practice parameters for the assessment and treatment of children, adolescents, and adults with autism and other pervasive developmental disorders. Journal Of The American Academy Of Child & Adolescent Psychiatry 1999, 38: 32s-54s. PMID: 10624084, DOI: 10.1016/s0890-8567(99)80003-3.Peer-Reviewed Original ResearchConceptsPervasive developmental disorderDevelopmental disordersRelated pervasive developmental disordersPatterns of delayCognitive skillsBehavioral problemsSyndrome expressionTreatment of childrenAutismCoordination of servicesPractice parametersTreatment modalitiesSustained interventionsMental retardationIndividualsDisordersClinical careAdolescentsDevianceSkillsFirst yearChildrenCareAdultsInterventionSummary of the Practice Parameters for the Assessment and Treatment of Children, Adolescents, and Adults With Autism and Other Pervasive Developmental Disorders
Volkmar F, Cook E, Pomeroy J, Realmuto G, Tanguay P. Summary of the Practice Parameters for the Assessment and Treatment of Children, Adolescents, and Adults With Autism and Other Pervasive Developmental Disorders. Journal Of The American Academy Of Child & Adolescent Psychiatry 1999, 38: 1611-1615. PMID: 10596264, DOI: 10.1097/00004583-199912000-00028.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildChild Development Disorders, PervasiveChild PsychiatryChild, PreschoolHumansConceptsPervasive developmental disorderDevelopmental disordersRelated pervasive developmental disordersTreatment of childrenPatterns of delayCognitive skillsBehavioral problemsSyndrome expressionAutismAdolescentsDisordersChildrenCoordination of servicesPractice parametersSustained interventionsTreatment modalitiesTreatment recommendationsMental retardationIndividualsClinical careDevianceSkillsFirst yearCliniciansTreatmentHigher-Functioning Pervasive Developmental Disorders: Rates and Patterns of Psychotropic Drug Use
MARTIN A, SCAHILL L, KLIN A, VOLKMAR F. Higher-Functioning Pervasive Developmental Disorders: Rates and Patterns of Psychotropic Drug Use. Journal Of The American Academy Of Child & Adolescent Psychiatry 1999, 38: 923-931. PMID: 10405512, DOI: 10.1097/00004583-199907000-00024.Peer-Reviewed Original ResearchConceptsPsychotropic drug useHigher-functioning pervasive developmental disordersPervasive developmental disorderTarget symptomsDrug useMedication use patternsPsychotropic medication useDevelopmental disordersMedication history informationMore medicationsMedication useClinical presentationPsychiatric comorbidityClinical variablesPsychotropic agentsDrug classesClinical heterogeneityDisordersSymptomsSubjectsAsperger's disorderFull Scale IQComorbiditiesMedicationsAntidepressantsAsk the Editor
Volkmar F. Ask the Editor. Journal Of Autism And Developmental Disorders 1999, 29: 185-186. PMID: 10382142, DOI: 10.1023/a:1023009230857.Peer-Reviewed Original ResearchExploring the Boundaries of Pervasive Developmental Disorder Not Otherwise Specified: Analyses of Data from the DSM-IV Autistic Disorder Field Trial
Buitelaar J, Van der Gaag R, Klin A, Volkmar F. Exploring the Boundaries of Pervasive Developmental Disorder Not Otherwise Specified: Analyses of Data from the DSM-IV Autistic Disorder Field Trial. Journal Of Autism And Developmental Disorders 1999, 29: 33-43. PMID: 10097993, DOI: 10.1023/a:1025966532041.Peer-Reviewed Original Research
1998
How Commonly Are Known Medical Conditions Associated with Autism?
Barton M, Volkmar F. How Commonly Are Known Medical Conditions Associated with Autism? Journal Of Autism And Developmental Disorders 1998, 28: 273-278. PMID: 9711483, DOI: 10.1023/a:1026052417561.Peer-Reviewed Original ResearchThe Vineland Adaptive Behavior Scales: Supplementary Norms for Individuals with Autism
Carter A, Volkmar F, Sparrow S, Wang J, Lord C, Dawson G, Fombonne E, Loveland K, Mesibov G, Schopler E. The Vineland Adaptive Behavior Scales: Supplementary Norms for Individuals with Autism. Journal Of Autism And Developmental Disorders 1998, 28: 287-302. PMID: 9711485, DOI: 10.1023/a:1026056518470.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdaptation, PsychologicalAdolescentAdultAnalysis of VarianceAutistic DisorderChildChild DevelopmentChild, PreschoolChi-Square DistributionCommunication DisordersDisability EvaluationFemaleHumansIntellectual DisabilityMaleMiddle AgedMotor SkillsMutismPsychiatric Status Rating ScalesPsychometricsReference ValuesSampling StudiesSocial BehaviorConceptsDaily living skillsMute individualsVerbal individualsVerbal skillsLiving skillsStandard scoresVineland Adaptive Behavior ScalesHigher standard scoresAdaptive Behavior ScalesPopulation normsVineland domainsVerbal childrenAutistic individualsMute childrenBehavior ScaleAutismGroup of individualsCommunication domainYoung childrenRelative weaknessYears of ageSkillsHigher scoresNational normsOlder individuals
1997
Risperidone Treatment of Children and Adolescents With Pervasive Developmental Disorders: A Prospective, Open-Label Study
MCDOUGLE C, HOLMES J, BRONSON M, ANDERSON G, VOLKMAR F, PRICE L, COHEN D. Risperidone Treatment of Children and Adolescents With Pervasive Developmental Disorders: A Prospective, Open-Label Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 1997, 36: 685-693. PMID: 9136504, DOI: 10.1097/00004583-199705000-00020.Peer-Reviewed Original ResearchConceptsPervasive developmental disorderDevelopmental disordersRisperidone treatmentClinical Global Impression ScaleOpen-label studyOpen-label trialPlacebo-controlled studyCommon side effectsEfficacy of risperidoneShort-term safetyGlobal Impression ScaleGlobal improvement itemBehavioral ratingsChildhood disintegrative disorderSocial relatednessTreatment of childrenAsperger's disorderRepetitive behaviorsAutistic disorderBehavioral symptomsBaseline visitMean ageImpression ScaleAdolescentsOptimal dose
1996
A Double-blind, Placebo-Controlled Study of Fluvoxamine in Adults With Autistic Disorder
McDougle C, Naylor S, Cohen D, Volkmar F, Heninger G, Price L. A Double-blind, Placebo-Controlled Study of Fluvoxamine in Adults With Autistic Disorder. JAMA Psychiatry 1996, 53: 1001-1008. PMID: 8911223, DOI: 10.1001/archpsyc.1996.01830110037005.Peer-Reviewed Original ResearchConceptsStudy of FluvoxamineAutistic disorderSelective serotonin uptake inhibitorAdverse cardiovascular eventsPlacebo-controlled trialWeeks of treatmentSerotonin uptake inhibitorSerotonin neurotransmitter systemShort-term treatmentCardiovascular eventsPlacebo groupMild sedationNeurotransmitter systemsTreatment responseSafe drugUptake inhibitorFluvoxamineSymptoms of autismFluvoxamine maleateDisordersPlaceboAutistic behaviorPatientsAdultsSymptomsChildhood and Adolescent Psychosis: A Review of the Past 10 Years
VOLKMAR F. Childhood and Adolescent Psychosis: A Review of the Past 10 Years. Journal Of The American Academy Of Child & Adolescent Psychiatry 1996, 35: 843-851. PMID: 8768343, DOI: 10.1097/00004583-199607000-00009.Peer-Reviewed Original ResearchAsperger's Syndrome
VOLKMAR F, KLIN A, SCHULTZ R, BRONEN R, MARANS W, SPARROW S, COHEN D. Asperger's Syndrome. Journal Of The American Academy Of Child & Adolescent Psychiatry 1996, 35: 118-123. PMID: 8567603, DOI: 10.1097/00004583-199601000-00020.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
1995
Validity and Neuropsychological Characterization of Asperger Syndrome: Convergence with Nonverbal Learning Disabilities Syndrome
Klin A, Volkmar F, Sparrow S, Cicchetti D, Rourke B. Validity and Neuropsychological Characterization of Asperger Syndrome: Convergence with Nonverbal Learning Disabilities Syndrome. Journal Of Child Psychology And Psychiatry 1995, 36: 1127-1140. PMID: 8847376, DOI: 10.1111/j.1469-7610.1995.tb01361.x.Peer-Reviewed Original Research