2023
Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing
Ibrahim L, Wamsley B, Alghamdi N, Yusuf N, Sevier E, Hairston A, Sherer M, Jaglin X, Xu Q, Guo L, Jamayran A, Favuzzi E, Yuan Y, Dimidschstein J, Darnell R, Fishell G. Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing. ELife 2023, 12: e86842. PMID: 37347149, PMCID: PMC10287156, DOI: 10.7554/elife.86842.Peer-Reviewed Original ResearchConceptsAlternative splicingSomatostatin interneuronsFamily of RNA-binding proteinsCortical circuit formationRNA-binding proteinsFamily of proteinsActivity-dependent alternative splicingNova familyMouse somatosensory cortexNOVA proteinsBear populationInhibitory cellsAxon formationSplicingSynaptic integrationGene expressionInterneuronsCircuit formationCortical circuitryActivity-dependentSomatosensory cortexSynapse formationBrain developmentSynaptic functionProtein
2018
Rbfox1 Mediates Cell-type-Specific Splicing in Cortical Interneurons
Wamsley B, Jaglin X, Favuzzi E, Quattrocolo G, Nigro M, Yusuf N, Khodadadi-Jamayran A, Rudy B, Fishell G. Rbfox1 Mediates Cell-type-Specific Splicing in Cortical Interneurons. Neuron 2018, 100: 846-859.e7. PMID: 30318414, PMCID: PMC6541232, DOI: 10.1016/j.neuron.2018.09.026.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAlternative SplicingAnimalsCerebral CortexInterneuronsMiceMice, Inbred C57BLMice, TransgenicOrgan Culture TechniquesRNA Splicing Factors