2022
Parenting boys with conduct problems and callous-unemotional traits: parent and child perspectives
Roberts R, McCrory E, Joffe H, Phillips H, Gaule A, Viding E. Parenting boys with conduct problems and callous-unemotional traits: parent and child perspectives. European Child & Adolescent Psychiatry 2022, 32: 2547-2555. PMID: 36374342, PMCID: PMC10682176, DOI: 10.1007/s00787-022-02109-0.Peer-Reviewed Original ResearchMeSH KeywordsCaregiversChildConduct DisorderEmotionsEmpathyHumansMaleParentingParentsProblem BehaviorConceptsCP/HCUCallous-unemotional traitsConduct problemsParents/caregiversTD boysInconsistent disciplineChildren’s perspectivesAlabama Parenting QuestionnaireParenting QuestionnaireChild monitoringMore difficultyLittle researchParentingQualitative reportsFamily engagementParentsSame perceptionCaregiversChild safetyBoysChildrenQualitative methodsDifficultiesExperienceCP intervention
2021
Modulation of Amygdala Response by Cognitive Conflict in Adolescents with Conduct Problems and Varying Levels of CU Traits
Sebastian C, Stafford J, McCrory E, Sethi A, De Brito S, Lockwood P, Viding E. Modulation of Amygdala Response by Cognitive Conflict in Adolescents with Conduct Problems and Varying Levels of CU Traits. Research On Child And Adolescent Psychopathology 2021, 49: 1043-1054. PMID: 33728508, PMCID: PMC8222043, DOI: 10.1007/s10802-021-00787-z.Peer-Reviewed Original ResearchConceptsCallous-unemotional traitsNegative emotional stimuliAmygdala responseConduct problemsEmotional stimuliCognitive conflictTask demandsCognitive task demandsCognitive conflict tasksLow callous-unemotional traitsCP/HCUHealthy adult sampleCognitive controlEmotional facesReactive aggressionAtypical modulationConflict taskNeurocognitive responsesAffect regulationCU traitsPotential translational relevanceConflict conditionsPrefrontal areasHigh conflictAdult samples
2020
Thinking about Others’ Minds: Mental State Inference in Boys with Conduct Problems and Callous-Unemotional Traits
Roberts R, McCrory E, Bird G, Sharp M, Roberts L, Viding E. Thinking about Others’ Minds: Mental State Inference in Boys with Conduct Problems and Callous-Unemotional Traits. Research On Child And Adolescent Psychopathology 2020, 48: 1279-1290. PMID: 32632744, PMCID: PMC7445196, DOI: 10.1007/s10802-020-00664-1.Peer-Reviewed Original ResearchConceptsMental state inferencesSocial judgment taskConduct problemsState inferenceMental statesCP/HCUCallous-unemotional traitsMind-related commentsSocial cognitionJudgment taskIntact abilityAntisocial actionsUnemotional TraitsPeople's thoughtsDifferent mindsGroup differencesMore difficultyBest friendTaskMindBoysNew measureDifferent aspectsThoughtCognition
2018
An fMRI investigation of empathic processing in boys with conduct problems and varying levels of callous-unemotional traits
Sethi A, O'Nions E, McCrory E, Bird G, Viding E. An fMRI investigation of empathic processing in boys with conduct problems and varying levels of callous-unemotional traits. NeuroImage Clinical 2018, 18: 298-304. PMID: 29876250, PMCID: PMC5987797, DOI: 10.1016/j.nicl.2018.01.027.Peer-Reviewed Original ResearchConceptsCP/HCUMedial prefrontal cortexCallous-unemotional traitsConduct problemsOwn emotionsAnterior cingulate cortexAnterior insulaEmpathic processingAffective experienceConjunction analysisACC/medial prefrontal cortexBrain areasBayes factor analysisEmpathy deficitsFMRI investigationTD groupNeural responsesConjunction effectOne's feelingsLess empathyEmotionsPrefrontal cortexNeutral scenarioCingulate cortexOccipital cortex
2017
Living with conduct problem youth: family functioning and parental perceptions of their child
Roberts R, McCrory E, Joffe H, De Lima N, Viding E. Living with conduct problem youth: family functioning and parental perceptions of their child. European Child & Adolescent Psychiatry 2017, 27: 595-604. PMID: 29204740, PMCID: PMC5945745, DOI: 10.1007/s00787-017-1088-6.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCaregiversChildChild DevelopmentConduct DisorderFamily RelationsFemaleHumansMalePerceptionProblem BehaviorConceptsConduct problemsFamily functioningParents/caregiversAffective involvementParental perceptionsConduct problem youthMcMaster Family Assessment DeviceFamily Assessment DeviceParents of childrenTD childrenShallow affectProblem youthFamily interventionsChild behaviorSpecific difficultiesAssessment DeviceFamily rolesExperience differencesMultiple domainsSpecific presentationFunctioningQualitative analysisGood rapportParentsChildrenConcurrent and Longitudinal Contribution of Exposure to Bullying in Childhood to Mental Health: The Role of Vulnerability and Resilience
Singham T, Viding E, Schoeler T, Arseneault L, Ronald A, Cecil C, McCrory E, Rijsdijk F, Pingault J. Concurrent and Longitudinal Contribution of Exposure to Bullying in Childhood to Mental Health: The Role of Vulnerability and Resilience. JAMA Psychiatry 2017, 74: 1112-1119. PMID: 28979965, PMCID: PMC5710218, DOI: 10.1001/jamapsychiatry.2017.2678.Peer-Reviewed Original ResearchConceptsYears of ageMental healthTwin differences designDissipation of effectsPopulation-based cohortContribution of exposureConduct problemsMental health assessmentPoor mental healthLongitudinal contributionMean ageSecondary interventionsTwins Early Development StudyMAIN OUTCOMEMultidimensional Peer Victimization ScalePeer Victimization ScaleChildhood exposureLast assessmentEarly Development StudyConcurrent anxietyPsychotic-like experiencesRole of vulnerabilityChildhoodAgeCognitive disorganizationUnderstanding the development of psychopathy: progress and challenges
Viding E, McCrory E. Understanding the development of psychopathy: progress and challenges. Psychological Medicine 2017, 48: 566-577. PMID: 29032773, DOI: 10.1017/s0033291717002847.Peer-Reviewed Original ResearchConceptsCU traitsCallous-unemotional traitsDevelopment of psychopathyExtant research findingsGroup of childrenInformative studiesDistress cuesResearch findingsIndividual differencesBrain activationProtective environmental factorsPsychopathyPrevention programsChildrenClinical implicationsStrong heritabilityClinical outcomesElevated riskEmpathyCuesTraitsGuiltHeritable riskFindingsAdulthood
2016
Regional grey matter volume and concentration in at-risk adolescents: Untangling associations with callous-unemotional traits and conduct disorder symptoms
Cohn M, Viding E, McCrory E, Pape L, van den Brink W, Doreleijers T, Veltman D, Popma A. Regional grey matter volume and concentration in at-risk adolescents: Untangling associations with callous-unemotional traits and conduct disorder symptoms. Psychiatry Research Neuroimaging 2016, 254: 180-187. PMID: 27479922, DOI: 10.1016/j.pscychresns.2016.07.003.Peer-Reviewed Original Research
2015
Grey Matter Volumes in Children with Conduct Problems and Varying Levels of Callous-Unemotional Traits
Sebastian C, De Brito S, McCrory E, Hyde Z, Lockwood P, Cecil C, Viding E. Grey Matter Volumes in Children with Conduct Problems and Varying Levels of Callous-Unemotional Traits. Research On Child And Adolescent Psychopathology 2015, 44: 639-649. PMID: 26364620, PMCID: PMC4830891, DOI: 10.1007/s10802-015-0073-0.Peer-Reviewed Original Research
2014
Neural bases of Theory of Mind in children with autism spectrum disorders and children with conduct problems and callous‐unemotional traits
O'Nions E, Sebastian C, McCrory E, Chantiluke K, Happé F, Viding E. Neural bases of Theory of Mind in children with autism spectrum disorders and children with conduct problems and callous‐unemotional traits. Developmental Science 2014, 17: 786-796. PMID: 24636205, PMCID: PMC4316185, DOI: 10.1111/desc.12167.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderAutism Diagnostic Observation ScheduleCP/HCUASD groupTemporoparietal junctionConduct problemsSpectrum disorderMedial prefrontal cortex responsesAtypical neural processingRight temporoparietal junctionPrefrontal cortex responsesCallous-unemotional traitsMedial prefrontal cortexAtypical processingToM processingVignette taskNeural levelNeural underpinningsNeural basisTD controlsNeural processingSocial difficultiesNeural responsesObservation ScheduleFMRI responses
2013
Association of Callous Traits with Reduced Neural Response to Others’ Pain in Children with Conduct Problems
Lockwood P, Sebastian C, McCrory E, Hyde Z, Gu X, De Brito S, Viding E. Association of Callous Traits with Reduced Neural Response to Others’ Pain in Children with Conduct Problems. Current Biology 2013, 23: 901-905. PMID: 23643836, PMCID: PMC3918856, DOI: 10.1016/j.cub.2013.04.018.Peer-Reviewed Original ResearchConceptsAnterior cingulate cortexFunctional magnetic resonance imagingConduct problemsNeural responsesAnterior insulaCallous traitsAdult psychopathyReduced blood oxygen level-dependent responsesAtypical neural responsesBlood oxygen level-dependent (BOLD) responseInferior frontal gyrusBilateral anterior insulaLevel-dependent responsesConsiderable societal costsEmpathic processingEmpathic deficitsEmpathic responsesFrontal gyrusAntisocial behaviorCingulate cortexACC responseEmpathyLarge samplePsychopathyNegative associationNeural responses to fearful eyes in children with conduct problems and varying levels of callous–unemotional traits
Sebastian C, McCrory E, Dadds M, Cecil C, Lockwood P, Hyde Z, De Brito S, Viding E. Neural responses to fearful eyes in children with conduct problems and varying levels of callous–unemotional traits. Psychological Medicine 2013, 44: 99-109. PMID: 23510564, DOI: 10.1017/s0033291713000482.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingSubgenual anterior cingulate cortexImportant translational implicationsNeural responsesAnterior cingulate cortexAmygdala responseMagnetic resonance imagingFearful eyesConduct problemsTrial participantsEye conditionsCingulate cortexCortex responsesResonance imagingEvidence baseAmygdala reactivityTranslational implicationsHeterogeneous groupTD controlsEyesChildrenFear recognition deficitsNeural levelParticipantsLow levels
2012
Amygdala Response to Preattentive Masked Fear in Children With Conduct Problems: The Role of Callous-Unemotional Traits
Viding E, Sebastian C, Dadds M, Lockwood P, Cecil C, De Brito S, McCrory E. Amygdala Response to Preattentive Masked Fear in Children With Conduct Problems: The Role of Callous-Unemotional Traits. American Journal Of Psychiatry 2012, 169: 1109-1116. PMID: 23032389, DOI: 10.1176/appi.ajp.2012.12020191.Peer-Reviewed Original ResearchConceptsHigh callous-unemotional traitsCallous-unemotional traitsLow callous-unemotional traitsConduct problemsAmygdala responseCalm facesAttention deficit hyperactivity disorderGreater amygdala responsesDifferential amygdala activityLower amygdala reactivityFindings complementMasked fearAffective processingComparison boysNeural basisAmygdala activityAmygdala reactivityConscious awarenessAmygdala involvementHyperactivity disorderNeural responsesUnemotional TraitsAmygdala hypoactivityClassification of childrenAmygdala hyperactivityNeural Responses to Affective and Cognitive Theory of Mind in Children With Conduct Problems and Varying Levels of Callous-Unemotional Traits
Sebastian C, McCrory E, Cecil C, Lockwood P, De Brito S, Fontaine N, Viding E. Neural Responses to Affective and Cognitive Theory of Mind in Children With Conduct Problems and Varying Levels of Callous-Unemotional Traits. JAMA Psychiatry 2012, 69: 814-822. PMID: 22868935, DOI: 10.1001/archgenpsychiatry.2011.2070.Peer-Reviewed Original ResearchConceptsCallous-unemotional traitsAffective processing taskConduct problemsNeural responsesCognitive theoryMind judgmentsUnique varianceAffective profilesAmygdala reactivityEmpathy componentsProcessing tasksAffective neural responsesDepression/anxiety symptomsConduct problem symptomsFunctional magnetic resonancePotential neural substratesConduct problem groupChildhood conduct problemsAffective stimuliNeural processingNeural substratesAnterior insulaUnemotional TraitsAnxiety symptomsRight amygdalaGenetic and neurocognitive contributions to the development of psychopathy
Viding E, McCrory E. Genetic and neurocognitive contributions to the development of psychopathy. Development And Psychopathology 2012, 24: 969-983. PMID: 22781866, DOI: 10.1017/s095457941200048x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAffectAntisocial Personality DisorderChildConduct DisorderEmpathyGuiltHumansParentingPersonality AssessmentConceptsCallous-unemotional traitsAntisocial behaviorDevelopmental neuroimaging studiesDevelopment of psychopathyPromising intervention approachNeurocognitive contributionsNeurocognitive vulnerabilityPositive parentingAntisocial childrenNeuroimaging studiesIntervention approachesConsistent rewardDevelopmental vulnerabilityParental involvementPreliminary evidenceCurrent evidence basePsychopathyEnvironmental influencesChildrenEvidence baseDistinct patternsPotential implicationsParentingInterventionRewardAntisocial behaviour in children with and without callous-unemotional traits
Viding E, Fontaine N, McCrory E. Antisocial behaviour in children with and without callous-unemotional traits. Journal Of The Royal Society Of Medicine 2012, 105: 195-200. PMID: 22637770, PMCID: PMC3360537, DOI: 10.1258/jrsm.2011.110223.Peer-Reviewed Original ResearchWhy should we care about measuring callous–unemotional traits in children?
Viding E, McCrory E. Why should we care about measuring callous–unemotional traits in children? The British Journal Of Psychiatry 2012, 200: 177-178. PMID: 22383762, DOI: 10.1192/bjp.bp.111.099770.Peer-Reviewed Original ResearchMeSH KeywordsAdoptionAntisocial Personality DisorderConduct DisorderHumansInstitutionalizationMalePsychosocial DeprivationConceptsClinical significance
2011
Predictors and Outcomes of Joint Trajectories of Callous–Unemotional Traits and Conduct Problems in Childhood
Fontaine N, McCrory E, Boivin M, Moffitt T, Viding E. Predictors and Outcomes of Joint Trajectories of Callous–Unemotional Traits and Conduct Problems in Childhood. Journal Of Psychopathology And Clinical Science 2011, 120: 730-742. PMID: 21341879, DOI: 10.1037/a0022620.Peer-Reviewed Original ResearchConceptsCU traitsConduct problemsFamily-level predictorsDevelopmental trajectoriesTwins Early Development StudyHigh CU traitsJoint developmental trajectoriesCallous-unemotional traitsGeneral growth mixture modelingEarly Development StudyGrowth mixture modelingUnemotional TraitsPsychosocial predictorsTeacher ratingsDelinquent behaviorLongitudinal researchNegative outcomesAdult psychopathyLongitudinal associationsAge 7Concomitant outcomesHigh trajectoryLow trajectoriesMixture modelingLarge sample
2010
Etiology of Different Developmental Trajectories of Callous-Unemotional Traits
Fontaine N, Rijsdijk F, McCrory E, Viding E. Etiology of Different Developmental Trajectories of Callous-Unemotional Traits. Journal Of The American Academy Of Child & Adolescent Psychiatry 2010, 49: 656-664. PMID: 20610135, DOI: 10.1016/j.jaac.2010.03.014.Peer-Reviewed Original Research