2013
Clinical malaria diagnosis in pregnancy in relation to early perinatal mother‐to‐child transmission of HIV: a prospective cohort study
Ezeamama A, Duggan C, Manji K, Spiegelman D, Hertzmark E, Bosch R, Kupka R, Okuma J, Kisenge R, Aboud S, Fawzi W. Clinical malaria diagnosis in pregnancy in relation to early perinatal mother‐to‐child transmission of HIV: a prospective cohort study. HIV Medicine 2013, 15: 276-285. PMID: 24215465, PMCID: PMC4299572, DOI: 10.1111/hiv.12111.Peer-Reviewed Original ResearchConceptsPregnant HIV-positive womenHIV-positive womenRelative riskFever symptomsHIV MTCTHIV infectionPolymerase chain reactionHIV-positive pregnant womenMultivariable logistic regression modelCent of HIVChild's HIV statusHIV MTCT riskInfants of womenPerinatal HIV infectionChild HIV infectionLaboratory-confirmed diagnosisConfidence intervalsPrenatal health careWeeks of lifeLogistic regression modelsHIV motherMaternal malariaMTCT programmeMTCT riskChild transmission
2003
High 18:2 Trans-Fatty Acids in Adipose Tissue Are Associated with Increased Risk of Nonfatal Acute Myocardial Infarction in Costa Rican Adults
Baylin A, Kabagambe EK, Ascherio A, Spiegelman D, Campos H. High 18:2 Trans-Fatty Acids in Adipose Tissue Are Associated with Increased Risk of Nonfatal Acute Myocardial Infarction in Costa Rican Adults. Journal Of Nutrition 2003, 133: 1186-1191. PMID: 12672941, DOI: 10.1093/jn/133.4.1186.Peer-Reviewed Original ResearchConceptsRisk of MICoronary heart diseaseMyocardial infarctionAdipose tissueTrans fatty acidsOdds ratioNonfatal acute myocardial infarctionTrans fatty acid intakeFirst nonfatal myocardial infarctionConditional logistic regression modelsNonfatal myocardial infarctionTrans FACosta Rican adultsAcute myocardial infarctionTotal adipose tissueAdipose tissue samplesArea of residenceIndividual trans fatty acidsLogistic regression modelsIncreased riskIncident casesAcid intakeRisk factorsAtherogenic potentialHeart diseaseAdipose Tissue α-Linolenic Acid and Nonfatal Acute Myocardial Infarction in Costa Rica
Baylin A, Kabagambe EK, Ascherio A, Spiegelman D, Campos H. Adipose Tissue α-Linolenic Acid and Nonfatal Acute Myocardial Infarction in Costa Rica. Circulation 2003, 107: 1586-1591. PMID: 12668490, DOI: 10.1161/01.cir.0000058165.81208.c6.Peer-Reviewed Original ResearchConceptsNonfatal acute myocardial infarctionAcute myocardial infarctionAdipose tissue alpha-linolenic acidAlpha-linolenic acidMyocardial infarctionCardiovascular diseaseFirst nonfatal acute myocardial infarctionMultivariate conditional logistic regression modelPopulation-based case-control studyConditional logistic regression modelsTissue linoleic acidMI risk factorsPopulation control subjectsCase-control studyAdipose tissue samplesArea of residenceLogistic regression modelsTrans fatty acidsΑ-Linolenic AcidCase patientsFatty acidsControl subjectsLowest quintileInverse associationRisk factors
2000
Proportion of colon cancer risk that might be preventable in a cohort of middle-aged US men
Platz E, Willett W, Colditz G, Rimm E, Spiegelman D, Giovannucci E. Proportion of colon cancer risk that might be preventable in a cohort of middle-aged US men. Cancer Causes & Control 2000, 11: 579-588. PMID: 10977102, DOI: 10.1023/a:1008999232442.Peer-Reviewed Original ResearchConceptsColon cancer riskMiddle-aged US menRisk factorsCancer riskRisk scoreUS menPopulation attributable risk percentColon cancer risk factorsHealth Professionals FollowModifiable risk factorsAttributable risk percentCancer risk factorsColon cancer incidenceLow-risk scoresRed meat consumptionColon cancer casesLogistic regression modelsProfessionals FollowCigarette smokingColorectal neoplasiaColorectal cancerPhysical inactivityCancer incidenceCancer casesFamily history
1999
Glutathione S -Transferase Mu and Theta Polymorphisms and Breast Cancer Susceptibility
García-Closas M, Kelsey K, Hankinson S, Spiegelman D, Springer K, Willett W, Speizer F, Hunter D. Glutathione S -Transferase Mu and Theta Polymorphisms and Breast Cancer Susceptibility. Journal Of The National Cancer Institute 1999, 91: 1960-1964. PMID: 10564681, DOI: 10.1093/jnci/91.22.1960.Peer-Reviewed Original ResearchConceptsGlutathione S-transferase mu 1Breast cancer riskBreast cancerGSTT1 null genotypeCancer riskOdds ratioNull genotypeGSTT1 genesConditional logistic regression modelsEndogenous mutagenic processesGlutathione S-transferase muConfidence intervalsGSTT1 gene deletionGSTT1 gene polymorphismsLogistic regression modelsHomozygous gene deletionBreast cancer susceptibilityTheta 1 genePremenopausal womenProspective cohortCigarette smokingIncident casesDecreased riskControl subjectsGSTT1 genotypeOral contraceptive use and risk of melanoma in premenopausal women
Feskanich D, Hunter DJ, Willett WC, Spiegelman D, Stampfer MJ, Speizer FE, Colditz GA. Oral contraceptive use and risk of melanoma in premenopausal women. British Journal Of Cancer 1999, 81: 918-923. PMID: 10555769, PMCID: PMC2374297, DOI: 10.1038/sj.bjc.6690787.Peer-Reviewed Original ResearchConceptsCurrent OC usersOral contraceptive useRisk of melanomaOC usersRisk factorsContraceptive useSun exposureHealth Study II cohortLow-dose oestrogen pillsPast OC usersBody mass indexPossible risk factorsLonger durationPremenopausal white womenLogistic regression modelsNHS IIOC usePremenopausal womenSignificant twofold increaseMass indexSuperficial spreadingNodular melanomaSkin reactionsIncidence rateSunburn history
1994
Clinical utility of chest auscultation in common pulmonary diseases.
Bettencourt PE, Del Bono EA, Spiegelman D, Hertzmark E, Murphy RL. Clinical utility of chest auscultation in common pulmonary diseases. American Journal Of Respiratory And Critical Care Medicine 1994, 150: 1291-1297. PMID: 7952555, DOI: 10.1164/ajrccm.150.5.7952555.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseCongestive heart failureInterstitial pulmonary fibrosisPulmonary diseaseMultiple logistic regression modelObstructive pulmonary diseaseCommon pulmonary conditionsCommon pulmonary diseasesLogistic regression modelsHeart failureRegression modelsPulmonary fibrosisLung diseasePulmonary conditionsChest auscultationClinical utilityCommon diseaseDiagnostic categoriesWave form analysisDiseaseSubjectsPneumoniaGroupFibrosisLung
1990
CORRECTION OF LOGISTIC REGRESSION RELATIVE RISK ESTIMATES AND CONFIDENCE INTERVALS FOR MEASUREMENT ERROR: THE CASE OF MULTIPLE COVARIATES MEASURED WITH ERROR
ROSNER B, SPIEGELMAN D, WILLETT WC. CORRECTION OF LOGISTIC REGRESSION RELATIVE RISK ESTIMATES AND CONFIDENCE INTERVALS FOR MEASUREMENT ERROR: THE CASE OF MULTIPLE COVARIATES MEASURED WITH ERROR. American Journal Of Epidemiology 1990, 132: 734-745. PMID: 2403114, DOI: 10.1093/oxfordjournals.aje.a115715.Peer-Reviewed Original ResearchConceptsAge-adjusted relative riskRelative riskRisk factorsFat intakeMultiple logistic regression modelBreast cancer riskConfidence intervalsTrue risk factorRelative risk estimatesValidation studyLogistic regression modelsMultivariate linear regression modelRegression modelsAlcohol intakeProspective studyDietary fatBreast cancerCancer riskLogistic regressionRisk estimatesIntakeRiskSeparate validation studyContinuous variablesPositive association