2024
Commentary: Health anxiety in youth during ‘COVID’ – some thoughts prompted by Rask et al. (2024)
Sonuga‐Barke E, Fearon P. Commentary: Health anxiety in youth during ‘COVID’ – some thoughts prompted by Rask et al. (2024). Journal Of Child Psychology And Psychiatry 2024, 65: 431-434. PMID: 38415840, DOI: 10.1111/jcpp.13973.Peer-Reviewed Original Research
2022
Adapting and testing a brief intervention to reduce maternal anxiety during pregnancy (ACORN): report of a feasibility randomized controlled trial
O’Mahen H, Ramchandani P, King D, Lee-Carbon L, Wilkinson E, Thompson-Booth C, Ericksen J, Milgrom J, Dunkley-Bent J, Halligan S, Fearon P. Adapting and testing a brief intervention to reduce maternal anxiety during pregnancy (ACORN): report of a feasibility randomized controlled trial. BMC Psychiatry 2022, 22: 129. PMID: 35177019, PMCID: PMC8851863, DOI: 10.1186/s12888-022-03737-1.Peer-Reviewed Original ResearchConceptsPregnant individualsBrief interventionPrimary care servicesPublic health benefitsNew brief interventionLarge-scale trialsMaternal prenatal anxietyUsual careIntervention armPrenatal clinicsLevel of anxietyMaternal anxietyTreatment groupsMaternity servicesCare servicesElevated symptomsPrenatal anxietyFurther evaluationMore sessionsHealth benefitsInterventionPregnancyMindfulness exercisesGroup sessionsAnxiety
2021
Maternal caregiving moderates the impact of antenatal maternal cortisol on infant stress regulation
Nazzari S, Fearon P, Rice F, Molteni M, Frigerio A. Maternal caregiving moderates the impact of antenatal maternal cortisol on infant stress regulation. Journal Of Child Psychology And Psychiatry 2021, 63: 871-880. PMID: 34787327, DOI: 10.1111/jcpp.13532.Peer-Reviewed Original ResearchConceptsInfant stress regulationInfant cortisol reactivityC-reactive proteinMaternal sensitive caregivingAntenatal stressMaternal cortisolCortisol responseInfant stress response systemsInfant cortisol regulationMaternal antenatal stressMaternal caregivingInfant cortisol responseCortisol reactivityGreater cortisol responseAntenatal exposureMaternal ageMaternal levelsInterleukin-6Late pregnancyMaternal stress signalsPostnatal depressionSensitive caregivingAnimal studiesStress regulationCortisol regulationDevelopmental trajectories of autistic social traits in the general population
Pender R, Fearon P, St Pourcain B, Heron J, Mandy W. Developmental trajectories of autistic social traits in the general population. Psychological Medicine 2021, 53: 814-822. PMID: 34154678, DOI: 10.1017/s0033291721002166.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderGrowth mixture modellingAutistic traitsSocial difficultiesCommunication Disorders ChecklistTrajectory groupsMajority-male groupsSCDC scoresAutistic peopleASD diagnosisSpectrum disorderDevelopmental trajectoriesCommunication traitsExternalising difficultiesAvon Longitudinal StudyTrait continuumGeneral population sampleAge 7Social traitsMental healthLongitudinal studyAdolescenceExternal validityPersistent lowYoung peopleDecision-making ability, psychopathology, and brain connectivity
Moutoussis M, Garzón B, Neufeld S, Bach D, Rigoli F, Goodyer I, Bullmore E, Consortium N, Fonagy P, Jones P, Hauser T, Romero-Garcia R, St Clair M, Vértes P, Whitaker K, Inkster B, Prabhu G, Ooi C, Toseeb U, Widmer B, Bhatti J, Villis L, Alrumaithi A, Birt S, Bowler A, Cleridou K, Dadabhoy H, Davies E, Firkins A, Granville S, Harding E, Hopkins A, Isaacs D, King J, Kokorikou D, Maurice C, McIntosh C, Memarzia J, Mills H, O’Donnell C, Pantaleone S, Scott J, Fearon P, Suckling J, van Harmelen A, Kievit R, Guitart-Masip M, Dolan R. Decision-making ability, psychopathology, and brain connectivity. Neuron 2021, 109: 2025-2040.e7. PMID: 34019810, PMCID: PMC8221811, DOI: 10.1016/j.neuron.2021.04.019.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAffectAntisocial Personality DisorderAnxietyBrainCognitionDecision MakingDepressionDepressive Disorder, MajorFactor Analysis, StatisticalFemaleFunctional NeuroimagingHumansIntelligence TestsMagnetic Resonance ImagingMaleNeural PathwaysNeuropsychological TestsPsychosocial FunctioningSelf ConceptSocial InteractionYoung AdultConceptsDecision-making abilityFunctional connectivityResting-state functional connectivityGeneral social functioningDecision-making measuresPoor social functionCognitive constructsCognitive processesBrain signaturesSocial functioningThought patternsBrain connectivityMental healthMultiple domainsSocial functionIQBrain dataCommon factorsYoung peopleConstructsIndividuals 18Neural networkConnectivityAbilityPsychopathology
2020
The chronicity and timing of prenatal and antenatal maternal depression and anxiety on child outcomes at age 5
Hentges R, Graham S, Fearon P, Tough S, Madigan S. The chronicity and timing of prenatal and antenatal maternal depression and anxiety on child outcomes at age 5. Depression And Anxiety 2020, 37: 576-586. PMID: 32419282, DOI: 10.1002/da.23039.Peer-Reviewed Original ResearchConceptsDepression/anxietyMaternal depressionAge 5Maternal anxietyLarge prospective pregnancy cohortMaternal anxiety/depressionMaternal mental health problemsAntenatal maternal depressionProspective pregnancy cohortMaternal mental healthMother-child pairsClinical screening toolAnxiety/depressionChild outcomesMental health problemsWeeks' gestationPregnancy cohortYear postpartumPostpartum periodNumber of exposuresChild development outcomesDepression symptomsHealth problemsPoor child outcomesScreening toolNeuroendocrine and immune markers of maternal stress during pregnancy and infant cognitive development
Nazzari S, Fearon P, Rice F, Ciceri F, Molteni M, Frigerio A. Neuroendocrine and immune markers of maternal stress during pregnancy and infant cognitive development. Developmental Psychobiology 2020, 62: 1100-1110. PMID: 32232990, DOI: 10.1002/dev.21967.Peer-Reviewed Original ResearchConceptsInfant cognitive developmentEarly cognitive developmentCognitive developmentAnxiety symptomsCognitive outcomesInfant cognitive outcomesMaternal depressiveC-reactive proteinCognitive development scoresMaternal stressHierarchical linear regressionInterleukin-6Maternal caregivingMaternal IQMaternal antenatal stressConcurrent anxietyAlpha-amylase concentrationsDiurnal cortisolSerum interleukin-6Healthy pregnant womenSalivary cortisolDevelopment scoresDepressive symptomsCurrent studyAntenatal exposure
2018
Networks of Depression and Anxiety Symptoms Across Development
McElroy E, Fearon P, Belsky J, Fonagy P, Patalay P. Networks of Depression and Anxiety Symptoms Across Development. Journal Of The American Academy Of Child & Adolescent Psychiatry 2018, 57: 964-973. PMID: 30522742, PMCID: PMC6290121, DOI: 10.1016/j.jaac.2018.05.027.Peer-Reviewed Original ResearchConceptsAnxiety symptomsEarly childhoodSymptom-symptom associationsBidirectional longitudinal associationsSpecific symptomsChild healthHuman Development StudySymptomsMaternal reportsLongitudinal associationsNetwork of depressionTime pointsStrong associationDepressionAge 5National InstituteCentral symptomsNonparametric permutation testsLongitudinal investigationDiagnostic boundariesSymptom structureEarly Child CareAssociationPresent studyChildhood
2016
Adapting and testing a brief intervention to reduce maternal anxiety during pregnancy (ACORN): study protocol for a randomised controlled trial
Wilkinson E, O’Mahen H, Fearon P, Halligan S, King D, Greenfield G, Dunkley-Bent J, Ericksen J, Milgrom J, Ramchandani P. Adapting and testing a brief intervention to reduce maternal anxiety during pregnancy (ACORN): study protocol for a randomised controlled trial. Trials 2016, 17: 156. PMID: 27006007, PMCID: PMC4804571, DOI: 10.1186/s13063-016-1274-8.Peer-Reviewed Original ResearchMeSH KeywordsAnxietyBody Temperature RegulationClinical ProtocolsCognitive Behavioral TherapyEnglandFeasibility StudiesFemaleHumansInfant, NewbornMidwiferyMother-Child RelationsPilot ProjectsPregnancyPregnancy ComplicationsPrenatal CarePsychiatric Status Rating ScalesPsychotherapy, BriefPsychotherapy, GroupQuality of LifeResearch DesignSleepTime FactorsTreatment OutcomeConceptsAntenatal anxietyBrief interventionMethods/designThis studyNumber of participantsRoutine antenatal carePost-intervention outcome measuresMeeting eligibility criteriaMother-child bondingParticipants meeting eligibility criteriaSymptoms of anxietyBackgroundNational guidelinesAntenatal careAntenatal servicesControlled TrialsIntervention armPerinatal populationFeasibility trialOutcome measuresMaternal anxietyNumber of sessionsCognitive-behavioral principlesEligibility criteriaDesignThis studyInfant sleepExpectant mothersPredicting treatment outcome in psychological treatment services by identifying latent profiles of patients
Saunders R, Cape J, Fearon P, Pilling S. Predicting treatment outcome in psychological treatment services by identifying latent profiles of patients. Journal Of Affective Disorders 2016, 197: 107-115. PMID: 26991365, DOI: 10.1016/j.jad.2016.03.011.Peer-Reviewed Original ResearchConceptsPsychological treatment servicesLatent profile analysisPsychological treatmentLatent profilesStandardized symptom measuresPsychological interventionsPsychological therapiesProfile analysisSymptom measuresSymptom domainsTreatment servicesTreatment outcomesSuitable interventionsLevel of attritionLongitudinal analysisBasic demographic informationInterventionDemographic informationAnxietyDifferent intensitiesTreatment responseOutcomesDepressionRoutine careDifferent groups
2013
Factorial invariance of the Patient Health Questionnaire and Generalized Anxiety Disorder Questionnaire
Ryan T, Bailey A, Fearon P, King J. Factorial invariance of the Patient Health Questionnaire and Generalized Anxiety Disorder Questionnaire. British Journal Of Clinical Psychology 2013, 52: 438-449. PMID: 24117915, PMCID: PMC4296344, DOI: 10.1111/bjc.12028.Peer-Reviewed Original ResearchConceptsGAD-7PHQ-9Patient Health Questionnaire depression scalePatient Health QuestionnaireGeneralized Anxiety Disorder QuestionnaireGeneralized Anxiety Disorder ScalePHQ-9 dataAnxiety Disorder QuestionnaireAnxiety Disorder ScaleConvergent validityPsychological Therapies (IAPT) programmePatient's symptomsHealth QuestionnaireDepression ScaleDisorder QuestionnaireIAPT servicesTherapy programScale's convergent validityAbstractTextEquivalent factor loadingsDisorder ScalePositive associationSymptomsFactor loadingsUnidimensional factor structure