2024
Trial protocol for the Building Resilience through Socio-Emotional Training (ReSET) programme: a cluster randomised controlled trial of a new transdiagnostic preventative intervention for adolescents
Viding E, Lloyd A, Law R, Martin P, Lucas L, Wu T, Steinbeis N, Midgley N, Veenstra R, Smith J, Ly L, Bird G, Murphy J, Plans D, Munafo M, Penton-Voak I, Deighton J, Richards K, Richards M, Fearon P. Trial protocol for the Building Resilience through Socio-Emotional Training (ReSET) programme: a cluster randomised controlled trial of a new transdiagnostic preventative intervention for adolescents. Trials 2024, 25: 143. PMID: 38395922, PMCID: PMC10885387, DOI: 10.1186/s13063-024-07931-2.Peer-Reviewed Original ResearchConceptsMental health problemsPost-interventionPreventive interventionsCluster randomised controlled trialPrevent mental health problemsHealth problemsRates of mental health disordersCluster-randomised designCommunication skills trainingTransdiagnostic preventive interventionMental health disordersSchool year levelRandomised controlled trialsSubgroup of participantsDiscussionThis projectScalable interventionsEmotional processingFollow-upMental wellbeingWeekly sessionsFocus groupsHealth disordersGroup-basedAssessed pre-Individual sessions
2017
Amygdala volume and hypothalamic-pituitary-adrenal axis reactivity to social stress
Barry T, Murray L, Fearon P, Moutsiana C, Johnstone T, Halligan S. Amygdala volume and hypothalamic-pituitary-adrenal axis reactivity to social stress. Psychoneuroendocrinology 2017, 85: 96-99. PMID: 28843903, PMCID: PMC5632999, DOI: 10.1016/j.psyneuen.2017.07.487.Peer-Reviewed Original ResearchConceptsAmygdala volumePostnatal depressionMaternal postnatal depressionTotal amygdala volumeCortisol reactivityAdrenal (HPA) axis reactivityLower cortisol reactivityAdrenal axisCortisol secretionControl offspringAxis reactivityYoung adultsAmygdalaEarly adversityStress reactivitySocial stressSocial stressorsPresent studyEmotional processingEmotional pathologyOffspringCentral rolePathologyHierarchical linear modellingBrain