Tyrone Cannon

2026

• 286. Schizophrenia Polygenic Risk, Deviations From Typical Brain Development, and Expected Brain Deficit Patterns in Individuals With Schizophrenia, Unaffected Relatives, and Healthy Controls

  Karalis J, Chavannes A, Zhu J, Trevorrow Z, Ferreira-Ianone S, Nuechterlein K, Asarnow R, Addington J, Cadenhead K, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Stone W, Tsuang M, Walker E, Woods S, Narr K, McEwen S, Ophoff R, Consortium N, Bearden C, Forsyth J. 286. Schizophrenia Polygenic Risk, Deviations From Typical Brain Development, and Expected Brain Deficit Patterns in Individuals With Schizophrenia, Unaffected Relatives, and Healthy Controls. Biological Psychiatry 2026, 99: s222. DOI: 10.1016/j.biopsych.2026.03.520.

  Peer-Reviewed Original Research

  Concepts

• 746. Distinct Pathways From Early Adversity to Poor Functioning in High-Risk Youth: The Roles of MMN and Neurocognition

  Carrion R, Dorvil S, Auther A, McLaughlin D, Ku B, Bachman P, Belger A, Duncan E, Hamilton H, Johannesen J, Light G, Niznikiewicz M, Roach B, Addington J, Bearden C, Cadenhead K, Cannon T, Keshavan M, Perkins D, Stone W, Walker E, Woods S, Mathalon D. 746. Distinct Pathways From Early Adversity to Poor Functioning in High-Risk Youth: The Roles of MMN and Neurocognition. Biological Psychiatry 2026, 99: s417-s418. DOI: 10.1016/j.biopsych.2026.03.980.

  Peer-Reviewed Original Research

• 664. Social Daily Stress, Epigenetic Age Acceleration, and Conversion to Psychosis Among Adolescents at Clinical High Risk for Psychosis

  Ku B, Xu Y, Arrant E, Addington J, Bearden C, Cadenhead K, Cannon T, Carrion R, Keshavan M, Mathalon D, Stone W, Woods S, Walker E, Perkins D, Huels A, Bozack A. 664. Social Daily Stress, Epigenetic Age Acceleration, and Conversion to Psychosis Among Adolescents at Clinical High Risk for Psychosis. Biological Psychiatry 2026, 99: s384. DOI: 10.1016/j.biopsych.2026.03.898.

  Peer-Reviewed Original Research

• 2. Mapping the Pathway From Neurocognition to Functioning in Youth at Clinical High Risk for Psychosis: Distinct Associations With Functional Capacity and Social Engagement

  Ma R, Carrión R, Cornblatt B, Addington J, Cadenhead K, Cannon T, Keshavan M, Mathalon D, Perkins D, Stone W, Tsuang M, Walker E, Woods S, Bearden C. 2. Mapping the Pathway From Neurocognition to Functioning in Youth at Clinical High Risk for Psychosis: Distinct Associations With Functional Capacity and Social Engagement. Biological Psychiatry 2026, 99: s75-s76. DOI: 10.1016/j.biopsych.2026.03.182.

  Peer-Reviewed Original Research

• Cannabis and Tobacco Co-Use Predicts Psychosis in Clinical High Risk Cohorts

  Bello D, Blyth S, Rabin R, Addington J, Bearden C, Cadenhead K, Cannon T, Carrión R, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Seidman L, Stone W, Tsuang M, Walker E, Woods S, Brady R, Ward H. Cannabis and Tobacco Co-Use Predicts Psychosis in Clinical High Risk Cohorts. Biological Psychiatry 2026, 99: s72. DOI: 10.1016/j.biopsych.2026.03.176.

  Peer-Reviewed Original Research

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• Biophysical modeling of excitation/inhibition balance and conversion to psychosis in the clinical high risk syndrome

  Rodriguez-Sanchez J, Hauke D, Pinotsis D, Berndt L, Oloye H, Nicholas S, Hamilton H, Roach B, Bachman P, Belger A, Carrión R, Duncan E, Johannesen J, Light G, Niznikiewicz M, Friston K, Addington J, Bearden C, Cadenhead K, Perkins D, Walker E, Woods S, Cannon T, Adams R, Mathalon D. Biophysical modeling of excitation/inhibition balance and conversion to psychosis in the clinical high risk syndrome. Biological Psychiatry 2026 PMID: 42025866, DOI: 10.1016/j.biopsych.2026.04.007.

  Peer-Reviewed Original Research

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• Cannabis and Tobacco Co-Use is Associated with Impaired Neurocognitive Performance in Individuals at Clinical High Risk for Psychosis

  Bello D, Connolly J, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Seidman L, Stone W, Tsuang M, Walker E, Woods S, Brady R, Carrión R, Ward H. Cannabis and Tobacco Co-Use is Associated with Impaired Neurocognitive Performance in Individuals at Clinical High Risk for Psychosis. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2026 PMID: 41999882, DOI: 10.1016/j.bpsc.2026.03.021.

  Peer-Reviewed Original Research

• Correlation networks of blood proteins in the neuroimmunology of schizophrenia—replication and extension

  Jeffries C, Bizon C, Ford J, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Seidman L, Stone W, Walker E, Woods S, Perkins D. Correlation networks of blood proteins in the neuroimmunology of schizophrenia—replication and extension. Translational Psychiatry 2026 PMID: 41965717, DOI: 10.1038/s41398-026-03934-6.

  Peer-Reviewed Original Research

• Social withdrawal and hippocampal volume among adolescents at clinical high risk for psychosis and healthy comparisons: The moderating role of neighborhood residential stability

  Ku B, Arrant E, Yuan Q, Aberizk K, Addington J, Bearden C, Cadenhead K, Cannon T, Carrión R, Keshavan M, Mathalon D, Perkins D, Stone W, Woods S, Walker E. Social withdrawal and hippocampal volume among adolescents at clinical high risk for psychosis and healthy comparisons: The moderating role of neighborhood residential stability. Schizophrenia Research 2026, 293: 81-90. PMID: 41955767, PMCID: PMC13094779, DOI: 10.1016/j.schres.2026.03.024.

  Peer-Reviewed Original Research

  Concepts

• Neighborhood social fragmentation and cerebello-thalamo-cortical connectivity in youth at clinical high-risk for psychosis and healthy comparisons

  Ku B, Arrant E, Addington J, Bearden C, Cadenhead K, Cannon T, Carrion R, Keshavan M, Mathalon D, Stone W, Woods S, Walker E, Perkins D, Cao H. Neighborhood social fragmentation and cerebello-thalamo-cortical connectivity in youth at clinical high-risk for psychosis and healthy comparisons. Brain And Environment 2026, 5: 100016. PMID: 41907310, PMCID: PMC13030900, DOI: 10.1016/j.braen.2026.100016.

  Peer-Reviewed Original Research

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