Ruth Feldman, PhD
About
Research
Publications
2024
Maternal mind-mindedness and infant oxytocin are interrelated and negatively associated with postnatal depression.
Lindley Baron-Cohen K, Fearon P, Meins E, Feldman R, Hardiman P, Rosan C, Fonagy P. Maternal mind-mindedness and infant oxytocin are interrelated and negatively associated with postnatal depression. Development And Psychopathology 2024, 1-12. PMID: 39363731, DOI: 10.1017/s0954579424001585.Peer-Reviewed Original ResearchMaternal mind-mindednessMind-mindednessMind-related commentsStudy 1Study 2Mothers' appropriate mind-related commentsLevels of mind-mindednessMothers' caregiving representationsPostnatal depressionSymptoms of depressionParent-child interactionsChildren's social developmentEffects of OTParent-child relationshipMaternal depression scoresChildren's early developmentSample of mothersCaregiving representationsChild OT levelsSalivary OTDepression scoresOT levelsMaternal-infant attachmentPlacebo-controlledDepressionSensitive infant care tunes a frontotemporal interbrain network in adolescence
Schwartz L, Hayut O, Levy J, Gordon I, Feldman R. Sensitive infant care tunes a frontotemporal interbrain network in adolescence. Scientific Reports 2024, 14: 22602. PMID: 39349700, PMCID: PMC11442694, DOI: 10.1038/s41598-024-73630-2.Peer-Reviewed Original ResearchConceptsFrontotemporal networkMaternal sensitivityInterbrain synchronyNaturalistic interactionsSocial communicationMother-child relationshipSocial-emotional outcomesPsychological well-beingEarly maternal behaviorMaternal intrusivenessPositive valenceInterbrain connectivityMaternal behaviorEarly adolescenceChild's brainHyperscanning studiesPost hoc comparisonsNeural synchronySocial orientationMaternal orientationLongitudinal studyAdolescentsWell-beingPost-hocChildrenMicrobiome Signature of Posttraumatic Stress Disorder and Resilience in Youth
Yirmiya K, Turjeman S, Shtossel O, Zagoory-Sharon O, Moadi L, Rubin E, Sharon E, Louzoun Y, Koren O, Feldman R. Microbiome Signature of Posttraumatic Stress Disorder and Resilience in Youth. Psychological Trauma Theory Research Practice And Policy 2024 PMID: 39023942, DOI: 10.1037/tra0001727.Peer-Reviewed Original ResearchPosttraumatic stress disorderPosttraumatic symptomatologyStress disorderResilient individualsMaternal caregivingPTSD phenotypeIncreased anxious behaviorEarly life stressTrauma-exposed youthWar-related traumaCross-species studiesEarly childhoodAnxious behaviorPosttraumatic symptomsLife stressAnxiety componentBehavior problemsLate adolescencePosttraumatic pathologyGerm-free miceBehavioral changesAdolescentsSymptomatologyMatched controlsMicrobial underpinningsInfants' salivary oxytocin and positive affective reactions to people
Zeng G, Leung T, Maylott S, Malik A, Adornato A, Lebowitz M, Messinger D, Szeto A, Feldman R, Simpson E. Infants' salivary oxytocin and positive affective reactions to people. Hormones And Behavior 2024, 164: 105579. PMID: 38905820, DOI: 10.1016/j.yhbeh.2024.105579.Peer-Reviewed Original ResearchOxytocin levelsSalivary oxytocinFacial affectAffective reactionsEarly Social Communication ScalesInfant positive affectStable individual differencesPositive facial affectSocial Communication ScalesHigher oxytocin levelsPositive affective reactionsSocio-emotional developmentPositive affectIndividual differencesSocial behaviorSmiling womenCommunication ScaleAffectOxytocinPhysiological measuresMonths of ageProsocialityStatistically significant changesU.S. infantsInfantsGeneration WhatsApp: inter-brain synchrony during face-to-face and texting communication
Schwartz L, Levy J, Hayut O, Netzer O, Endevelt-Shapira Y, Feldman R. Generation WhatsApp: inter-brain synchrony during face-to-face and texting communication. Scientific Reports 2024, 14: 2672. PMID: 38302582, PMCID: PMC10834538, DOI: 10.1038/s41598-024-52587-2.Peer-Reviewed Original ResearchConceptsBrain-to-brain synchronySocial brain functionFronto-temporal networkInter-brain connectivityMother-adolescent dyadsPre-registered studyLive social interactionInter-brain synchronyFace-to-face interactionInterbrain synchronyBehavioral synchronyBrain functionNeural synchronyFace-to-faceNeural connectionsSocial interactionFace-to-face conversationFace-to-face communicationInterpersonal connectionsModes of communicationTechnology-based communicationEffects of textingDegree of improvementText communicationSocial exchangeIntranasal Oxytocin Combined With Social Skills Training for Schizophrenia: An Add-on Randomized Controlled Trial
Saporta-Wiesel L, Feldman R, Levi L, Davidson M, Burshtein S, Gur R, Zagoory-Sharon O, Amiaz R, Park J, Davis J, Weiser M. Intranasal Oxytocin Combined With Social Skills Training for Schizophrenia: An Add-on Randomized Controlled Trial. Schizophrenia Bulletin Open 2024, 5: sgae022. PMID: 39502135, PMCID: PMC11535855, DOI: 10.1093/schizbullopen/sgae022.Peer-Reviewed Original ResearchSocial skills trainingSymptoms of schizophreniaSkills trainingSupportive psychotherapyNegative symptoms of schizophreniaTreatment of negative symptomsSocial interactionBaseline to end-of-studyBlunted affectNegative symptomsPANSS scoresIntranasal oxytocinPositive affectSocial dysfunctionSchizophreniaRandomized controlled trialsTotal scoreSocial behaviorPost hoc analysisPANSSPsychotherapyOxytocinHigh dose oxytocinAffectEnd-of-study
2023
Neurophysin I is an analytically robust surrogate biomarker for oxytocin
MacLean E, Carranza E, Gnanadesikan G, King K, Allen A, Linde-Krieger L, Feldman R, White-Traut R, Hammock E, Carter C, Leng G, Tecot S, Bell A. Neurophysin I is an analytically robust surrogate biomarker for oxytocin. Psychoneuroendocrinology 2023, 161: 106951. PMID: 38194845, PMCID: PMC10872509, DOI: 10.1016/j.psyneuen.2023.106951.Peer-Reviewed Original ResearchSurrogate biomarkerOxytocin concentrationsUseful surrogate biomarkerRegulation of appetitePlasma oxytocin concentrationsNP-1Late pregnancyImmune functionKnockout micePleiotropic neuropeptideUrine samplesPlasma oxytocinCardiovascular repairOxytocinBiomarkersSandwich immunoassayStudy of vasopressinEquimolar concentrationsHuman plasmaBreast milk oxytocin and s-IgA modulate infant biomarkers and social engagement; The role of maternal anxiety
Zagoory-Sharon O, Yirmiya K, Peleg I, Shimon-Raz O, Sanderlin R, Feldman R. Breast milk oxytocin and s-IgA modulate infant biomarkers and social engagement; The role of maternal anxiety. Comprehensive Psychoneuroendocrinology 2023, 17: 100219. PMID: 38187086, PMCID: PMC10765300, DOI: 10.1016/j.cpnec.2023.100219.Peer-Reviewed Original ResearchBreast milkInfant salivaS-IgAInfant biomarkersMaternal anxietyBreast milk compositionMaternal mental healthMother-infant dyadsInfant social behaviorInfant immunityInfant healthSecretory immunoglobulinS-IgA.Mother-infant bondSame biomarkersMental healthAbundant antibodyBiomarkersOxytocinSalivaMental developmentImmunityAssociationDegree of stressHealth
2009
Parental Brain Activity In Response to Baby Stimuli Varies with Mood and Correlates with Parent-Infant Interactions
Swain J, Kim P, Feldman R, Leckman J. Parental Brain Activity In Response to Baby Stimuli Varies with Mood and Correlates with Parent-Infant Interactions. NeuroImage 2009, 47: s184. DOI: 10.1016/s1053-8119(09)72039-7.Peer-Reviewed Original Research
News
News
- February 19, 2020Source: Romper
Netflix's 'Babies' Documents Fatherly Attachment To Babies: Watch
- February 12, 2020Source: Aeon
The biology of love
- December 02, 2013Source: Yale News
A single spray of oxytocin improves brain function in children with autism
- December 02, 2013
A single spray of oxytocin improves brain function in children with autism