Lakshmi Bangalore, PhD
Lecturer in NeurologyDownloadHi-Res Photo
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Associate Director, Strategic Planning and Communications, Center for Neuroscience and Regeneration Research
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About
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Lecturer in Neurology
Associate Director, Strategic Planning and Communications, Center for Neuroscience and Regeneration Research
Biography
Funding support is vital for driving advancements in medical research. My expertise lies in scientific communications, where I transform complex research findings into clear, compelling, and scientifically accurate content tailored to diverse audiences. As liaison between medical researchers, funding bodies, and other stakeholders, I play a key role in advancing strategic research and development objectives through effective collaboration and communications.
Specialties: Scientific Writing and Editing, Scientific Storytelling, Project Management, Publications Planning, Scientific Liaison, Program Development
Appointments
Education & Training
- PhD
- Yale University, Molecular, Cellular and Developmental Biology
Advanced Training & Certifications
- Graduate Certificate in Science Writing
- Johns Hopkins University
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Lakshmi Bangalore's published research.
Publications Timeline
A big-picture view of Lakshmi Bangalore's research output by year.
Andrew Tan, PhD
David F. Stern, PhD
Jared King, MS
Shujun Liu
Sierra Dawn Kauer
Stephen Waxman, MD, PhD
16Publications
220Citations
Publications
2024
A FAIR, open-source virtual reality platform for dendritic spine analysis
Reimer M, Kauer S, Benson C, King J, Patwa S, Feng S, Estacion M, Bangalore L, Waxman S, Tan A. A FAIR, open-source virtual reality platform for dendritic spine analysis. Patterns 2024, 5: 101041. PMID: 39568639, PMCID: PMC11573899, DOI: 10.1016/j.patter.2024.101041.Peer-Reviewed Original ResearchAltmetricConceptsVirtual realityVirtual reality platformSoftware ecosystemReality platformData standardSuperior accuracyDatasetWorkflowValidation processDendritic spine morphologySpine analysisDendritic spinesReconstruction techniqueSpine lengthMethod's superior accuracyDendritic spine lengthSpine morphologyMetricsMorphological metricsNeurodataFairness
2021
Conditional RAC1 knockout in motor neurons restores H-reflex rate-dependent depression after spinal cord injury
Benson CA, Olson KL, Patwa S, Reimer ML, Bangalore L, Hill M, Waxman SG, Tan AM. Conditional RAC1 knockout in motor neurons restores H-reflex rate-dependent depression after spinal cord injury. Scientific Reports 2021, 11: 7838. PMID: 33837249, PMCID: PMC8035187, DOI: 10.1038/s41598-021-87476-5.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSpinal cord injuryDendritic spine dysgenesisMotor neuronsSpine dysgenesisSCI animalsHyperexcitability disordersCord injurySpinal alpha motor neuronsVentral horn motor neuronsAbnormal dendritic spine morphologyRac1 knockoutH-reflex pathwayRate-dependent depressionAlpha motor neuronsDevelopment of spasticityAdeno-associated viralMushroom dendritic spinesSpine head sizeOverall spine lengthDendritic spine morphologyRac1 protein expressionNeuronal hyperexcitabilityMajor complicationsClinical symptomsReflex excitability
2020
Core principles for the implementation of the neurodata without borders data standard
Reimer ML, Bangalore L, Waxman SG, Tan AM. Core principles for the implementation of the neurodata without borders data standard. Journal Of Neuroscience Methods 2020, 348: 108972. PMID: 33157146, DOI: 10.1016/j.jneumeth.2020.108972.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsBig data analyticsData standardsData analyticsDatabase interfaceJupyter notebooksBig data analytics applicationsData analytics applicationsData analytical capabilitiesNeurophysiology dataDatabase technologyDatabase operationsInternational Brain LaboratoryAnalytics applicationsData queryData integrityData sharingProcess transparencyExisting methodsDiverse modalitiesAnalyticsDesign principlesSingle formatNeurodataHistorical dataDiverse sourcesDendritic Spine Dynamics after Peripheral Nerve Injury: An Intravital Structural Study
Benson CA, Fenrich KK, Olson KL, Patwa S, Bangalore L, Waxman SG, Tan AM. Dendritic Spine Dynamics after Peripheral Nerve Injury: An Intravital Structural Study. Journal Of Neuroscience 2020, 40: 4297-4308. PMID: 32371602, PMCID: PMC7252482, DOI: 10.1523/jneurosci.2858-19.2020.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsDendritic spine dynamicsInjury-induced painPeripheral nerve injuryNeuropathic painDorsal hornSpine dynamicsNerve injuryPeripheral nerve injury-induced painNerve injury-induced painSuperficial dorsal horn neuronsSpinal cord dorsal hornDorsal horn neuronsSuperficial dorsal hornMechanisms of painDendritic spine dysgenesisContext of injuryPostmortem tissue analysisSame dendritic branchRepeat imagingMale miceMedical conditionsEffective treatmentPainSpine dysgenesisDendritic spines
2019
Spinal cord motor neuron plasticity accompanies second‐degree burn injury and chronic pain
Patwa S, Benson CA, Dyer L, Olson K, Bangalore L, Hill M, Waxman SG, Tan AM. Spinal cord motor neuron plasticity accompanies second‐degree burn injury and chronic pain. Physiological Reports 2019, 7: e14288. PMID: 31858746, PMCID: PMC6923170, DOI: 10.14814/phy2.14288.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSecond-degree burn injuryCentral nervous systemBurn injuryDrug withdrawalMajor public health challengeMotor neuron plasticityDendritic spine densityAlpha motor neuronsInjury-induced changesDendritic spine dysgenesisNervous system traumaDendritic spine changesPublic health challengeThermal burn injurySpinal cord sensoryDendritic spine morphologyMotor neuron structureChronic painSpine densitySystem traumaNeuron plasticitySpinal cordIntractable complicationMotor neuronsSensory disorders
2016
Dendritic spine remodeling following early and late Rac1 inhibition after spinal cord injury: evidence for a pain biomarker
Zhao P, Hill M, Liu S, Chen L, Bangalore L, Waxman SG, Tan AM. Dendritic spine remodeling following early and late Rac1 inhibition after spinal cord injury: evidence for a pain biomarker. Journal Of Neurophysiology 2016, 115: 2893-2910. PMID: 26936986, PMCID: PMC4922610, DOI: 10.1152/jn.01057.2015.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSpinal cord injuryNeuropathic painDendritic spine dysgenesisDendritic spinesCord injurySpine dysgenesisDorsal horn neuronsSpine profilesDendritic spine remodelingEffective clinical translationSensory dysfunctionSignificant complicationsNociceptive systemPain biomarkersSpine remodelingClinical conditionsPreclinical studiesRac1 activityEffective treatmentPainDrug responsivenessStructural biomarkersDisease statesRac1 inhibitionBiomarkers
1999
Mutations in the heatshock cognate 70 protein (hsc4) modulate Notch signaling.
Hing HK, Bangalore L, Sun X, Artavanis-Tsakonas S. Mutations in the heatshock cognate 70 protein (hsc4) modulate Notch signaling. European Journal Of Cell Biology 1999, 78: 690-7. PMID: 10569241, DOI: 10.1016/S0171-9335(99)80037-5.Peer-Reviewed Original Research
1997
Synergy between suppressor of Hairless and Notch in regulation of Enhancer of split m gamma and m delta expression.
Eastman DS, Slee R, Skoufos E, Bangalore L, Bray S, Delidakis C. Synergy between suppressor of Hairless and Notch in regulation of Enhancer of split m gamma and m delta expression. Molecular And Cellular Biology 1997, 17: 5620-8. PMID: 9271437, PMCID: PMC232410.Peer-Reviewed Original Research
1992
Antiserum raised against a synthetic phosphotyrosine-containing peptide selectively recognizes p185neu/erbB-2 and the epidermal growth factor receptor.
Bangalore L, Tanner AJ, Laudano AP, Stern DF. Antiserum raised against a synthetic phosphotyrosine-containing peptide selectively recognizes p185neu/erbB-2 and the epidermal growth factor receptor. Proceedings Of The National Academy Of Sciences Of The United States Of America 1992, 89: 11637-11641. PMID: 1280833, PMCID: PMC50608, DOI: 10.1073/pnas.89.23.11637.Peer-Reviewed Original ResearchCitationsAltmetricAn extra cysteine proximal to the transmembrane domain induces differential cross-linking of p185neu and p185neu.
Cao H, Bangalore L, Dompé C, Bormann BJ, Stern DF. An extra cysteine proximal to the transmembrane domain induces differential cross-linking of p185neu and p185neu. Journal Of Biological Chemistry 1992, 267: 20489-20492. PMID: 1356980, DOI: 10.1016/s0021-9258(19)88728-8.Peer-Reviewed Original ResearchCitations
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- August 03, 2023
Clinical Trial Builds Upon Yale Studies to Provide Proof-of-Concept that Subtype-specific Sodium Channel Blockers can Reduce Pain in Humans
- February 16, 2022
NIH Awards HEAL Grant to Study Novel Ways to Treat Pain
- October 23, 2019
Scientists Discover How Nerve Cells Build Their Electrically Excitable Membranes