Publications

2025

Tracing the evolution of single-cell 3D genomes in Kras-driven cancers
Liu M, Jin S, Agabiti S, Jensen T, Yang T, Radda J, Ruiz C, Baldissera G, Rajaei M, Li F, Townsend J, Muzumdar M, Wang S. Tracing the evolution of single-cell 3D genomes in Kras-driven cancers. Nature Genetics 2025, 1-13. PMID: 40825871, DOI: 10.1038/s41588-025-02297-w.
Peer-Reviewed Original Research
Concepts
Direct genetic transformation bypasses tumor-associated DNA methylation alterations
Hetzel S, Hodis E, Torlai Triglia E, Kovacsovics A, Steinmann K, Gnirke A, Cui M, McQuaid D, Weigert R, Pohl G, Muzumdar M, Leyvraz S, Keilholz U, Yaspo M, Regev A, Kretzmer H, Smith Z, Meissner A. Direct genetic transformation bypasses tumor-associated DNA methylation alterations. Genome Biology 2025, 26: 212. PMID: 40676699, PMCID: PMC12273271, DOI: 10.1186/s13059-025-03650-2.
Peer-Reviewed Original Research
MeSH Keywords and Concepts

2024

2023

Oligomeric organization of membrane proteins from native membranes at nanoscale spatial and single-molecule resolution
Walker G, Brown C, Ge X, Kumar S, Muzumdar M, Gupta K, Bhattacharyya M. Oligomeric organization of membrane proteins from native membranes at nanoscale spatial and single-molecule resolution. Nature Nanotechnology 2023, 19: 85-94. PMID: 38012273, PMCID: PMC10981947, DOI: 10.1038/s41565-023-01547-4.
Peer-Reviewed Original Research
Concepts
Decoding the obesity–cancer connection: lessons from preclinical models of pancreatic adenocarcinoma
Ruiz C, Garcia C, Jacox J, Lawres L, Muzumdar M. Decoding the obesity–cancer connection: lessons from preclinical models of pancreatic adenocarcinoma. Life Science Alliance 2023, 6: e202302228. PMID: 37648285, PMCID: PMC10474221, DOI: 10.26508/lsa.202302228.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Physical Restraints in Advanced Illness #462
McQuaid D, Roberts A, Lescott S, Prsic E. Physical Restraints in Advanced Illness #462. Journal Of Palliative Medicine 2023, 26: 1150-1152. DOI: 10.1089/jpm.2023.0174.
Peer-Reviewed Original Research
Erratum. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes 2023;72:433-448.
Mastracci T, Apte M, Amundadottir L, Alvarsson A, Artandi S, Bellin M, Bernal-Mizrachi E, Caicedo A, Campbell-Thompson M, Cruz-Monserrate Z, Ouaamari A, Gaulton K, Geisz A, Goodarzi M, Hara M, Hull-Meichle R, Kleger A, Klein A, Kopp J, Kulkarni R, Muzumdar M, Naren A, Oakes S, Olesen S, Phelps E, Powers A, Stabler C, Tirkes T, Whitcomb D, Yadav D, Yong J, Zaghloul N, Pandol S, Sander M. Erratum. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes 2023;72:433-448. Diabetes 2023, 72: 1173. PMID: 37116182, PMCID: PMC10382644, DOI: 10.2337/db23-er08.
Peer-Reviewed Original Research
Concepts
Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings.
Mastracci T, Apte M, Amundadottir L, Alvarsson A, Artandi S, Bellin M, Bernal-Mizrachi E, Caicedo A, Campbell-Thompson M, Cruz-Monserrate Z, El Ouaamari A, Gaulton K, Geisz A, Goodarzi M, Hara M, Hull-Meichle R, Kleger A, Klein A, Kopp J, Kulkarni R, Muzumdar M, Naren A, Oakes S, Olesen S, Phelps E, Powers A, Stabler C, Tirkes T, Whitcomb D, Yadav D, Yong J, Zaghloul N, Pandol S, Sander M. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes 2023, 72: 433-448. PMID: 36940317, PMCID: PMC10033248, DOI: 10.2337/db22-0942.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Oligomeric distribution of membrane proteins in native-membrane environment at nanoscale spatial and single-molecule resolution
Walker G, Brown C, Ge X, Gupta K, Muzumdar M, Bhattacharyya M. Oligomeric distribution of membrane proteins in native-membrane environment at nanoscale spatial and single-molecule resolution. Biophysical Journal 2023, 122: 457a. DOI: 10.1016/j.bpj.2022.11.2457.
Peer-Reviewed Original Research
Concepts

Publications

2025

Tracing the evolution of single-cell 3D genomes in Kras-driven cancers

Direct genetic transformation bypasses tumor-associated DNA methylation alterations

2024

Keep It Moving: Physical Activity in the Prevention of Obesity-Driven Pancreatic Cancer.

Perioperative Modified FOLFIRINOX for Resectable Pancreatic Cancer

994 NANOSTRING GEOMX SPATIAL TRANSCRIPTOMIC ANALYSIS OF PANCREATIC ISLETS IN DIABETIC AND NONDIABETIC PANCREATIC CANCER PATIENTS REVEALS BETA CELL DEDIFFERENTIATION ASSOCIATED WITH ER STRESS PATHWAYS AND ALTERED LIPID METABOLISM

Imaging nanoscale-spatial oligomeric organization of membrane proteins directly from native membranes at single-molecule resolution

2023

Oligomeric organization of membrane proteins from native membranes at nanoscale spatial and single-molecule resolution

Decoding the obesity–cancer connection: lessons from preclinical models of pancreatic adenocarcinoma

Physical Restraints in Advanced Illness #462

Erratum. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes 2023;72:433-448.

Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings.

Oligomeric distribution of membrane proteins in native-membrane environment at nanoscale spatial and single-molecule resolution

2022

Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases

IRF8 as a Novel Marker to Differentiate Between CD30-Positive Large Cell Lymphomas

Global assessment of IRF8 as a novel cancer biomarker

2021

Establishment of a novel mesenchymal stem cell-based regimen for chronic myeloid leukemia differentiation therapy

5‐Fluorouracil efficacy requires anti‐tumor immunity triggered by cancer‐cell‐intrinsic STING

2020

Cryptic Cachexia

Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma

2019

Identification of DHODH as a therapeutic target in small cell lung cancer

Treatment of obesity-related inflammation with a novel synthetic pentacyclic oleanane triterpenoids via modulation of macrophage polarization

2018

iRGD-guided tumor-penetrating nanocomplexes for therapeutic siRNA delivery to pancreatic cancer

Small molecule activators of protein phosphatase 2A for the treatment of castration-resistant prostate cancer.

Differences in Nanoparticle Uptake in Transplanted and Autochthonous Models of Pancreatic Cancer

Adaptive and Reversible Resistance to Kras Inhibition in Pancreatic Cancer Cells