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Glucagon-like peptide-1 (GLP-1) agonists are showing promise for reducing both cardiometabolic disease prevalence and obesity stigma.

Dr. Jeremy Jacox, a medical oncologist at Yale Cancer Center. Dr. Jacox, joined Good Morning Connecticut at 9 a.m to discuss advances in pancreatic cancer research.

Using new technology, Yale researchers examine cancer progression in single cells to visualize and understand its evolution from pre-cancerous to advanced disease in mouse models. Next steps include human tissue.

A new clinical trial is showing MRNA vaccines could help people who have pancreatic cancer. Dr. Jeremy Jacox, medical oncologist at Yale Cancer Center and Smilow Cancer Hospital, spoke about this research with NBC Connecticut.

“When the study launched, even with operable pancreatic cancers, 90% of patients were still relapsing and dying from their cancer eventually,” said Dr. Michael Cecchini, the first author of the study and the co-director of the colorectal program at the Center for Gastrointestinal Cancers at Smilow Cancer Hospital and YCC. “We sought to move chemotherapy up in their treatment regimen and give it before surgery to see if we could improve the outcome for our patients.”

On November 16, 2023, members of the Center for Gastrointestinal Cancers at Smilow Cancer Hospital and Yale Cancer Center presented on endoscopic management, surgery, radiation therapy, therapies and clinical trials for pancreatic adrenal carcinoma.

This inaugural event marked the launch of the Cancer Metabolism Initiative (CAMI), which aims to bring together investigators from across the campus to shape the future of cancer metabolism.

The Damon Runyon Cancer Research Foundation has announced eight recipients of the 2023 Damon Runyon-Rachleff Innovation Award, established to support “high-risk, high-reward” ideas with the potential to significantly impact the prevention, diagnosis, or treatment of cancer.

The Lustgarten Foundation announced today that a 2022 Innovation and Collaboration Program grant will be awarded to Mandar Muzumdar, MD, Co-Director of Pancreas Program, Center for Gastrointestinal Cancers at Smilow Cancer Hospital and Yale Cancer Center for his study "Dietary oleic acid reprograms pancreatic lipid metabolism to drive cancer development."