Dylan Gee, PhD
Associate Professor TenureCards
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Featured Publications
Neural circuitry involved in conditioned inhibition via safety signal learning is sensitive to trauma exposure
Kribakaran S, Odriozola P, Cohodes E, McCauley S, Zacharek S, Hodges H, Haberman J, Pierre J, Gee D. Neural circuitry involved in conditioned inhibition via safety signal learning is sensitive to trauma exposure. Neurobiology Of Stress 2022, 21: 100497. PMID: 36532365, PMCID: PMC9755062, DOI: 10.1016/j.ynstr.2022.100497.Peer-Reviewed Original ResearchLeveraging the science of stress to promote resilience and optimize mental health interventions during adolescence
Gee DG, Sisk LM, Cohodes EM, Bryce NV. Leveraging the science of stress to promote resilience and optimize mental health interventions during adolescence. Nature Communications 2022, 13: 5693. PMID: 36171218, PMCID: PMC9519553, DOI: 10.1038/s41467-022-33416-4.Peer-Reviewed Original ResearchNeural effects of controllability as a key dimension of stress exposure
Cohodes EM, Odriozola P, Mandell JD, Caballero C, McCauley S, Zacharek SJ, Hodges HR, Haberman JT, Smith M, Thomas J, Meisner OC, Ellis CT, Hartley CA, Gee DG. Neural effects of controllability as a key dimension of stress exposure. Development And Psychopathology 2022, 35: 218-227. PMID: 35034670, DOI: 10.1017/s0954579421001498.Peer-Reviewed Original ResearchConceptsDorsal anterior insulaRight dorsal anterior insulaUncontrollable stress conditionUncontrollable stressStress exposureSex-matched participantsStressor controllabilityInitial exposureFunctional magnetic resonance imaging (fMRI) acquisitionSubsequent stress exposureNeural effectsAnterior insulaYoung adultsSubsequent stressorsPatterns of activityCross-species evidenceNeural correlatesSubsequent exposureExposureNeural underpinningsPresent studyParticipantsMagnetic resonance imaging (MRI) acquisitionAdaptive responseFMRI analysisEarly Adversity and Development: Parsing Heterogeneity and Identifying Pathways of Risk and Resilience
Gee DG. Early Adversity and Development: Parsing Heterogeneity and Identifying Pathways of Risk and Resilience. American Journal Of Psychiatry 2021, 178: 998-1013. PMID: 34734741, DOI: 10.1176/appi.ajp.2021.21090944.Peer-Reviewed Original ResearchConceptsEarly adversityProtective factorsEffects of adversityOnset of psychopathologyPathways of riskNeurodevelopmental trajectoriesMajor risk factorAdversityMental healthNeurodevelopmental pathwaysEarly environmentPsychopathologySpecific dimensionsIntervention strategiesFuture researchRisk factorsEarly risk identificationTreatment approachesImmense burdenConceptual modelDevelopmental timingResilienceOngoing refinementRiskFactorsAssociations among negative life events, changes in cortico-limbic connectivity, and psychopathology in the ABCD Study
Brieant AE, Sisk LM, Gee DG. Associations among negative life events, changes in cortico-limbic connectivity, and psychopathology in the ABCD Study. Developmental Cognitive Neuroscience 2021, 52: 101022. PMID: 34710799, PMCID: PMC8556598, DOI: 10.1016/j.dcn.2021.101022.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityNegative life eventsLife eventsInternalizing symptomsAdversity exposureCortico-limbic connectivityParental acceptanceAdolescent Brain Cognitive Development (ABCD) studyLongitudinal structural equation modelLower internalizing symptomsCognitive Development StudyContext of adversityIndirect effectsSample of youthStressful childhood experiencesCortico-limbic networkStructural equation modelLater psychopathologyNeurobiological maturationInternalizing problemsABCD studyFunctional connectivityChildhood experiencesPotential protective effectPsychopathology
2025
Person-centered analyses reveal that developmental adversity at moderate levels and neural threat/safety discrimination are associated with lower anxiety in early adulthood
Sisk L, Keding T, Ruiz S, Odriozola P, Kribakaran S, Cohodes E, McCauley S, Zacharek S, Hodges H, Haberman J, Pierre J, Caballero C, Baskin-Sommers A, Gee D. Person-centered analyses reveal that developmental adversity at moderate levels and neural threat/safety discrimination are associated with lower anxiety in early adulthood. Communications Psychology 2025, 3: 31. PMID: 40044923, PMCID: PMC11882445, DOI: 10.1038/s44271-025-00193-x.Peer-Reviewed Original ResearchNeural activityAdverse exposuresMiddle childhoodLower anxietyAssociated with lower anxietyWithin-person combinationsPerson-centered analysesPerson-centered approachHigher neural activityPatterns of adversity exposureCorticolimbic circuitryModerate adversityParsing heterogeneityAnxiety symptomsSafety learningDevelopmental adversityLatent profilesLifetime adversityNeurobiological functionsFuture anxietyAnxietyEarly adulthoodAssociated with processesAdversityYoung adultsMultivariate links between the developmental timing of adversity exposure and white matter tract connectivity in adulthood
Sisk L, Keding T, Cohodes E, McCauley S, Pierre J, Odriozola P, Kribakaran S, Haberman J, Zacharek S, Hodges H, Caballero C, Gold G, Huang A, Talton A, Gee D. Multivariate links between the developmental timing of adversity exposure and white matter tract connectivity in adulthood. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2025 PMID: 39978462, DOI: 10.1016/j.bpsc.2025.02.003.Peer-Reviewed Original ResearchWhite matter tractsAdverse exposuresPreschool-ageMiddle childhoodMental health in adulthoodDevelopment of white matter tractsEarly-life adversitySymptoms in adulthoodChildhood adversity exposureDevelopmental timing of exposureMental health problemsTiming of adversity exposureMental health burdenCortico-cortical communicationIncreased mental health burdenTract connectivityNeurobiological changesHealth in adulthoodModes of covariationSensorimotor functionMultivariate linksMental healthAdversityAdulthoodHealth burdenDynamics Between Affect and Social Acceptance as a Function of Social Anxiety: A Person-Specific Network Approach
Gunther K, Edelman A, Petrie D, Kober H, Gee D, Joormann J, Gadassi-Polack R. Dynamics Between Affect and Social Acceptance as a Function of Social Anxiety: A Person-Specific Network Approach. Emotion 2025, 25: 46-56. PMID: 39207390, DOI: 10.1037/emo0001370.Peer-Reviewed Original ResearchEtiology of social anxiety disorderSocial anxiety disorderSocial anxietyPositive affectAnxiety disordersDevelopmental period of increased riskFunction of social anxietySocial anxiety symptomsDaily diary dataSocial acceptanceBenefits of acceptanceSocial experiencePerson-centered approachPeriod of increased riskRegulate affectAnxiety symptomsSocial cuesAnxietyAffectDevelopmental periodPerson-specificAdolescentsDiary dataReturn to baselineDisordersHeterogeneity in Developmental Trajectories of Internalizing and Externalizing Symptomatology: Associations with Risk and Protective Factors
Brieant A, Cai T, Ip K, Holt-Gosselin B, Gee D. Heterogeneity in Developmental Trajectories of Internalizing and Externalizing Symptomatology: Associations with Risk and Protective Factors. Child Psychiatry & Human Development 2025, 1-12. PMID: 39786680, DOI: 10.1007/s10578-024-01804-0.Peer-Reviewed Original ResearchAdolescent Brain Cognitive DevelopmentHigh-decreasing classModerate-increasing classTrajectories of psychopathologyNegative life eventsLow-stable classSample of youthLow-decreasing classGrowth mixture modelingProtective factorsExternalizing symptomatologyPsychopathological trajectoriesExternalizing symptomsProportion of youthLife eventsDevelopmental trajectoriesPsychopathologyCognitive developmentExternalizing trajectoriesTrajectory classesParental acceptanceLatent classesDevelopmental patternsInternational trajectoriesCo-development
2024
Associations between parental psychopathology and youth functional emotion regulation brain networks
Karl V, Beck D, Eilertsen E, Morawetz C, Wiker T, Aksnes E, Norbom L, Ferschmann L, MacSweeney N, Voldsbekk I, Andreassen O, Westlye L, Gee D, Engen H, Tamnes C. Associations between parental psychopathology and youth functional emotion regulation brain networks. Developmental Cognitive Neuroscience 2024, 70: 101476. PMID: 39541797, PMCID: PMC11609324, DOI: 10.1016/j.dcn.2024.101476.Peer-Reviewed Original ResearchParental psychopathologyYouth psychopathologyEmotion regulationAssociated with children's emotion regulationResting-state functional magnetic resonance imaging dataAdolescent Brain Cognitive Development StudyIntergenerational transmission of psychopathologyAssociated with lower connectivityFunctional magnetic resonance imaging dataTransmission of psychopathologyChildren's emotion regulationCognitive Development StudyMagnetic resonance imaging dataParental mental healthPFC networksPsychopathologyBrain networksParental internalizingMediation analysisCognitive aspectsMental healthConnectivity patternsIntergenerational transmissionNetwork connectivityYouth
Academic Achievements & Community Involvement
News
News
- March 05, 2025Source: Yale News
For Some, Childhood Adversity Can Promote Resilience to Anxiety Disorders
- January 08, 2025
Study Led by Gee Named a 2024 Leading Research Achievement by BBRF
- June 10, 2024
Yale Child Study Center welcomes 2024 summer interns
- October 06, 2023Source: The New York Times
How to Break Through When Your Teen Tunes You Out
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