Jian Yue, PhD
Postdoctoral Associate (Microbial Pathogenesis)About
Titles
Postdoctoral Associate (Microbial Pathogenesis)
Biography
Dr. Yue earned his Ph.D. in Biochemistry and Molecular Biology from the University of Science and Technology of China in December, 2020, and also worked as a postdoctoral researcher at the Southern University of Science and Technology. Dr. Yue utilizes various techniques, such as X-ray crystallography, cryo-electron microscopy (cryo-EM), and biochemical methods, to investigate the structure-function relationship of proteins involved in critical physiological processes in bacterial, yeast, and human cells.
In May 2023, Dr. Jian joined the Liu laboratory at Yale School of Medicine and the Microbial Sciences Institute to further develop his expertise in cryo-electron tomography (cryo-ET) and correlative approaches. He investigates bacterial type IV secretion system (T4SS), utilizing high-throughput cryo-ET techniques to visualize and determine high-resolution 3D structures in their native context.
Appointments
Microbial Pathogenesis
Postdoctoral AssociatePrimary
Other Departments & Organizations
Education & Training
- PhD
- University of Science and Technology of China, Biochemistry and Molecular Biology
Research
Overview
Medical Research Interests
- View Lab Website
Liu Lab
Publications
2022
Cryo-EM structures of the human surfactant lipid transporter ABCA3.
Xie T, Zhang Z, Yue J, Fang Q, Gong X. Cryo-EM structures of the human surfactant lipid transporter ABCA3. Sci Adv 2022, 8: eabn3727. PMID: 35394827, DOI: 10.1126/sciadv.abn3727.Peer-Reviewed Original Research
2020
Distinct oligomeric structures of the YoeB-YefM complex provide insights into the conditional cooperativity of type II toxin-antitoxin system.
Xue L, Yue J, Ke J, Khan MH, Wen W, Sun B, Zhu Z, Niu L. Distinct oligomeric structures of the YoeB-YefM complex provide insights into the conditional cooperativity of type II toxin-antitoxin system. Nucleic Acids Res 2020, 48: 10527-10541. PMID: 32845304, DOI: 10.1093/nar/gkaa706.Peer-Reviewed Original Research