Neurobiological Correlates of Psychedelic Experiences and Psychedelic-Associated Adverse Effects
Rieser N, Schmidt T, Preller K. Neurobiological Correlates of Psychedelic Experiences and Psychedelic-Associated Adverse Effects. Current Topics In Behavioral Neurosciences 2024, 1-20. PMID: 39080245, DOI: 10.1007/7854_2024_507.Peer-Reviewed Original ResearchCortico-striato-thalamo-corticalPsychedelic experiencePathophysiology of psychiatric illnessPsychedelic drug actionEffects of psychedelicsHuman neuroimaging studiesAcute drug effectsEffects of psychedelic drugsEntropic brain hypothesisNeurobiological correlatesEgo dissolutionNeural correlatesNeurobiological mechanismsNeuroimaging studiesNeural mechanismsPsychiatric illnessPsychedelic drugsBrain hypothesisDrug effectsPET measurementsSubacute adverse effectsDrug actionGeneral effectEmotional impactLong-term adverse effectsKnowledge gaps in psychedelic medicalisation: Preclinical and neuroimaging mechanisms
McCulloch D, Lopez J, Dalla C, Castrén E, Erritzoe D, Frokjaer V, Lundberg J, Preller K, Fisher P, Knudsen G. Knowledge gaps in psychedelic medicalisation: Preclinical and neuroimaging mechanisms. Neuroscience Applied 2024, 3: 103929. DOI: 10.1016/j.nsa.2023.103929.Peer-Reviewed Original ResearchSerotonin 2A receptorFunctional brain activityMechanism of actionClinical effectsPreclinical modelsBrain disordersClinical neuroimagingDose optimizationNeurotransmitter releaseEffects of psychedelicsBrain activitySex differencesPsychedelic drugsMolecular mechanismsKnowledge gapsPsychedelicsAppropriate behavioral modelsPreclinicalNeuroimagingReceptors