2018
The Role of Stress in the Pathogenesis and Maintenance of Obsessive-Compulsive Disorder
Adams T, Kelmendi B, Brake C, Gruner P, Badour C, Pittenger C. The Role of Stress in the Pathogenesis and Maintenance of Obsessive-Compulsive Disorder. Chronic Stress 2018, 2: 2470547018758043. PMID: 29527593, PMCID: PMC5841259, DOI: 10.1177/2470547018758043.Peer-Reviewed Original ResearchOnset of symptomsOCD symptomatologyNeuronal hypertrophyNeuronal atrophyPathophysiological relationshipLimbic circuitsLimbic circuitryFrontal cortexDorsolateral striatumPsychosocial stressGoal-directed learningNeural abnormalitiesPsychiatric symptomatologyDorsomedial striatumPreclinical researchNonspecific factorsRole of stressSymptomsCompulsive disorderSymptomatologyStriatumOCD symptomsPathogenesisIndependent causeTraumatic incidents
2015
Are There Biological Commonalities Among Different Psychiatric Disorders?
Etkin A, Pittenger C. Are There Biological Commonalities Among Different Psychiatric Disorders? 2015, 243-257. DOI: 10.1002/9781118753378.ch15.Peer-Reviewed Original ResearchPsychiatric diseasesDifferent disordersMajor depressive disorderSame brain circuitsDifferent psychiatric disordersAnterior cingulate cortexDorsolateral prefrontal cortexDepressive disorderDorsal striatumPsychiatric disordersCingulate cortexOverlapping symptomatologyBrain circuitsVentral striatumBiological commonalitiesBrain functionPrefrontal cortexDisordersNormal functionDrug addictionStriatumCortexDiseaseDiagnosisSymptomatology