2010
Lynx for Braking Plasticity
Higley MJ, Strittmatter SM. Lynx for Braking Plasticity. Science 2010, 330: 1189-1190. PMID: 21109660, PMCID: PMC3244692, DOI: 10.1126/science.1198983.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAgingAmblyopiaAnimalsChondroitin Sulfate ProteoglycansDominance, OcularMembrane GlycoproteinsMiceMice, KnockoutNeuronal PlasticityNeuropeptidesNicotinic AntagonistsReceptors, ImmunologicReceptors, NicotinicSensory DeprivationSignal TransductionVision, OcularVisual CortexVisual PathwaysConceptsVisual cortex plasticityVisual cortex neuronsNicotinic acetylcholine receptorsJuvenile plasticityNeurological performanceCortex neuronsJuvenile brainOcular dominanceAdult miceAcetylcholine receptorsVisual cortexAdult animalsSensory inputAdultsYoung mammalsMiceMedical implicationsEyesSuch plasticityPlasticityCortexNeuronsBrainReceptors
1999
A PDZ Protein Regulates the Distribution of the Transmembrane Semaphorin, M-SemF*
Wang L, Kalb R, Strittmatter S. A PDZ Protein Regulates the Distribution of the Transmembrane Semaphorin, M-SemF*. Journal Of Biological Chemistry 1999, 274: 14137-14146. PMID: 10318831, DOI: 10.1074/jbc.274.20.14137.Peer-Reviewed Original ResearchConceptsPDZ proteinsG-protein signal transduction pathwaySingle PDZ domainDetergent-resistant aggregatesSignal transduction pathwaysAxon guidance signalsPDZ domainCytoplasmic domainProtein interactionsTransduction pathwaysTransmembrane semaphorinsExpression studiesFour residuesGAIPSubcellular distributionHEK293 cellsSemaphorin familyCell surfaceProteinNeural proteinsGuidance signalsInteractsGIPCPDZSemaphorins
1991
The neuronal growth cone as a specialized transduction system
Strittmatter S, Fishman M. The neuronal growth cone as a specialized transduction system. BioEssays 1991, 13: 127-134. PMID: 1831353, DOI: 10.1002/bies.950130306.Peer-Reviewed Original ResearchConceptsGene programGrowth conesNeuronal growth conesExtracellular stimuliEnvironmental signalsExtracellular signalsMembrane proteinsTransduction systemCell shapeGrowth cone behaviorExtracellular matrixGrowth cone activityCone behaviorGrowth programMechanical forcesNeuronal growthProteinTransduction devicesIntrinsic factorsGAP-43Molecular sitesGTPPossible componentsSitesCone activity
1988
Characterization of a neutral, divalent cation-sensitive endopeptidase: a possible role in neuropeptide processing.
Supattapone S, Strittmatter SM, Fricker LD, Snyder SH. Characterization of a neutral, divalent cation-sensitive endopeptidase: a possible role in neuropeptide processing. Brain Research 1988, 427: 173-81. PMID: 3382941, DOI: 10.1016/0169-328x(88)90063-0.Peer-Reviewed Original ResearchConceptsCorpus striatumBrain regionsTissue distributionBovine adrenal chromaffin granulesAdrenal chromaffin granulesHomogeneous tissue distributionPossible roleNeuropeptide processingDensity gradient fractionationSucrose density gradient fractionationEndopeptidaseLeu-ArgChromaffin granulesHigh levelsBasic amino acidsTrypsin-like endopeptidaseEnzyme activityHippocampusStriatum