1988
Enkephalin convertase: characterization and localization using [3H]guanidinoethylmercaptosuccinic acid
Lynch D, Venable J, Strittmatter S, Snyder S. Enkephalin convertase: characterization and localization using [3H]guanidinoethylmercaptosuccinic acid. Biochimie 1988, 70: 57-64. PMID: 3135843, DOI: 10.1016/0300-9084(88)90158-7.Peer-Reviewed Original Research
1986
Enkephalin convertase: localization to specific neuronal pathways
Lynch DR, Strittmatter SM, Venable JC, Snyder SH. Enkephalin convertase: localization to specific neuronal pathways. Journal Of Neuroscience 1986, 6: 1662-1675. PMID: 3086516, PMCID: PMC6568706, DOI: 10.1523/jneurosci.06-06-01662.1986.Peer-Reviewed Original ResearchConceptsSpecific neuronal pathwaysPyramidal cellsDentate gyrusStria terminalisNeuronal pathwaysAcid lesionsBed nucleusCaudate nucleusGranule cellsSubstantia nigra pars reticulataDentate gyrus granule cellsKnife-cut lesionsGyrus granule cellsQuinolinic acid lesionsHypothalamic magnocellular nucleiIbotenic acid lesionsWhite matter tractsBrain tissue sectionsPars reticulataTrigeminal ganglionKainic acidEnkephalinergic pathwaysLateral septumSensory neuronsMedian eminenceCharacterization of angiotensin converting enzyme by [3H]captopril binding.
Strittmatter SM, Snyder SH. Characterization of angiotensin converting enzyme by [3H]captopril binding. Molecular Pharmacology 1986, 29: 142-8. PMID: 3005826.Peer-Reviewed Original ResearchConceptsEnzyme-inhibitor interactionsActive site Zn2Dissociation rate constantsPure enzyme preparationCatalysisEnzyme moleculesNM-1 min-1Characterization of angiotensinRate constantsEnzyme preparationSubstrate catalysisSedimentation experimentsGel filtrationIonsMin-1Polypeptide chainBinding sitesIsomerizationMonophasic associationBindingZn2L-leucineMoleculesChloridePurification
1985
Differential visualization of dopamine and norepinephrine uptake sites in rat brain using [3H]mazindol autoradiography
Javitch JA, Strittmatter SM, Snyder SH. Differential visualization of dopamine and norepinephrine uptake sites in rat brain using [3H]mazindol autoradiography. Journal Of Neuroscience 1985, 5: 1513-1521. PMID: 4009243, PMCID: PMC6565258, DOI: 10.1523/jneurosci.05-06-01513.1985.Peer-Reviewed Original ResearchConceptsDA uptake sitesNE uptake sitesUptake sitesRat brainSubstantia nigra pars compactaAnterior olfactory nucleusVentral tegmental areaIbotenic acid lesionsAnteroventral thalamusNoradrenergic terminalsOlfactory nucleusSolitary tractMazindol bindingPars compactaSomatodendritic regionOlfactory tubercleDopaminergic axonsLocus coeruleusNorepinephrine uptakeTegmental areaPeriventricular nucleusSubthalamic nucleusIbotenic acidStria terminalisAcid lesions
1984
Angiotensin-Converting Enzyme in the Male Rat Reproductive System: Autoradiographic Visualization with [3H]Captopril*
STRITTMATTER S, SNYDER S. Angiotensin-Converting Enzyme in the Male Rat Reproductive System: Autoradiographic Visualization with [3H]Captopril*. Endocrinology 1984, 115: 2332-2341. PMID: 6094156, DOI: 10.1210/endo-115-6-2332.Peer-Reviewed Original ResearchConceptsACE activityMale rat reproductive systemRat reproductive systemSoluble ACE activityAutoradiographic silver grainsStages I-VIIIInitial segmentMale ratsAutoradiographic visualizationPharmacological profileTesticular slicesBasal epitheliumSilver grainsLuminal labellingReproductive tractInterstitial tissueMonoclonal antibodiesVas deferensSeminiferous tubulesLevel of bindingReproductive systemLuminal surfaceEpitheliumAutoradiographic visualization of angiotensin-converting enzyme in rat brain with [3H]captopril: localization to a striatonigral pathway.
Strittmatter SM, Lo MM, Javitch JA, Snyder SH. Autoradiographic visualization of angiotensin-converting enzyme in rat brain with [3H]captopril: localization to a striatonigral pathway. Proceedings Of The National Academy Of Sciences Of The United States Of America 1984, 81: 1599-1603. PMID: 6324207, PMCID: PMC344885, DOI: 10.1073/pnas.81.5.1599.Peer-Reviewed Original ResearchConceptsCaudate putamenSubstantia nigraStriatonigral pathwayRat brainAngiotensin II involvementIpsilateral caudate putamenTrans-synaptic changesIpsilateral substantia nigraMedian preoptic areaAngiotensin-converting enzymeLack of effectStriatal interneuronsAngiotensin IIEntopeduncular nucleusNeuronal perikaryaSubfornical organZona reticulataGlobus pallidusACE activityLocus coeruleusParaventricular nucleusPreoptic areaIbotenic acidMedial habenulaNeuronal pathways