A new role for Nogo as a regulator of vascular remodeling
Acevedo L, Yu J, Erdjument-Bromage H, Miao RQ, Kim JE, Fulton D, Tempst P, Strittmatter SM, Sessa WC. A new role for Nogo as a regulator of vascular remodeling. Nature Medicine 2004, 10: 382-388. PMID: 15034570, DOI: 10.1038/nm1020.Peer-Reviewed Original ResearchConceptsSmooth muscle cellsVascular remodelingMuscle cellsVascular smooth muscle cellsCentral nervous systemIntact blood vesselsVascular injuryAxonal regenerationNeointimal proliferationMice promotesKnockout miceNervous systemVascular homeostasisFamily of proteinsVascular expansionEndothelial cellsBlood vesselsNogoNogo isoformsLipid raftsProteomic analysisN-terminusRemodelingGene transferCells