Combination of NEP 1-40 Treatment and Motor Training Enhances Behavioral Recovery After a Focal Cortical Infarct in Rats
Fang PC, Barbay S, Plautz EJ, Hoover E, Strittmatter SM, Nudo RJ. Combination of NEP 1-40 Treatment and Motor Training Enhances Behavioral Recovery After a Focal Cortical Infarct in Rats. Stroke 2010, 41: 544-549. PMID: 20075346, PMCID: PMC2853474, DOI: 10.1161/strokeaha.109.572073.Peer-Reviewed Original ResearchConceptsMotor trainingWeeks postinfarctBehavioral recoverySkilled reachWeek 2Focal cortical infarctsFocal cortical ischemiaFocal ischemic infarctTreatment week 2Foot-fault testFocal ischemic injuryWeeks of treatmentSkilled reach taskNEP 1Cortical infarctsForelimb impairmentCortical ischemiaFoot faultsMotor recoveryIschemic infarctIschemic injuryMotor cortexEndothelin-1Intraventricular infusionMotor function