Project INSPIRE

Project INSPIRE was a randomized, double-blind, placebo-controlled trial of extended-release injectable naltrexone (Brand name: Vivitrol) for treatment of alcohol dependence and hazardous drinking among HIV-infected individuals transitioning from prison to the community. A total of 125 incarcerated, HIV-infected individuals who met pre-incarceration DSM-IV criteria for alcohol dependence or hazardous drinking and were within 6 months of reentry to the community were enrolled in the study. Primary outcomes for this study were retention in HIV care, time to relapse to alcohol use, and acceptability of medication assisted therapy.

Funding provided by:
National Institute on Drug Abuse

Project Period:

September 1, 2009 – August 31, 2014

Link to Report:
Project Inspire at projectreporter.nih.gov

Faculty

Frederick Lewis Altice, MD, MA
Principal Investigator
Professor of Medicine (Infectious Diseases) and of Epidemiology (Microbial Diseases); Affiliated Faculty, Yale Institute for Global Health; Director, Yale Center for Clinical and Community Research, Department of Medicine; Director, HIV in Prisons Program, Infectious Diseases; Director, Community Health Care Van, Intersection of Infectious Diseases and Substance Use Disorders/Addiction Medicine; Academic Icon Professor of Medicine, University of Malaya-Centre of Excellence for Research in AIDS (CERiA), Faculty of Medicine
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Sandra Ann Springer, MD
Principal Investigator
Professor of Medicine (AIDS) and Associate Clinical Professor of Nursing; Director, Infectious Disease Outpatient Clinic, Veterans Administration Healthcare Services, Newington
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