Featured Publications
Cumulative Anticholinergic Exposure Is Associated with Poor Memory and Executive Function in Older Men
Han L, Agostini JV, Allore HG. Cumulative Anticholinergic Exposure Is Associated with Poor Memory and Executive Function in Older Men. Journal Of The American Geriatrics Society 2008, 56: 2203-2210. PMID: 19093918, PMCID: PMC3952110, DOI: 10.1111/j.1532-5415.2008.02009.x.Peer-Reviewed Original ResearchConceptsTotal anticholinergic burdenCumulative anticholinergic exposureOlder menAnticholinergic medicationsAnticholinergic burdenAnticholinergic exposureCumulative exposureVeterans Affairs primary care clinicsExecutive functionAnticholinergic medication useDeleterious adverse effectsProspective cohort studySeverity of hypertensionCommunity-dwelling menPrimary care clinicsDaily Living ScalePotential risk factorsPrescription of drugsAnticholinergic scoreCohort studyMultiple medicationsAnticholinergic effectsMedication useCare clinicsPhysical function
2013
The impact of medication use on symptom burden in older patients with multiple medical morbidities
Han M, Tinetti M, Agostini J, Han L, Lee H, Walke L. The impact of medication use on symptom burden in older patients with multiple medical morbidities. Journal Of Clinical Gerontology And Geriatrics 2013, 4: 84-88. DOI: 10.1016/j.jcgg.2013.03.002.Peer-Reviewed Original ResearchSymptom burdenMedical morbidityMedication useVeterans Affairs primary care clinicsGreater medication useMultiple medical morbiditiesNumber of medicationsMedical record reviewPrimary care clinicsSurvey of patientsAdverse drug eventsCross-sectional studySeverity of symptomsAdditional medicationOlder patientsCare clinicsRecord reviewRoutine appointmentsDrug eventsChi-square analysisMorbiditySevere symptomsMedicationsLinear regression analysisSymptom categories
2007
Association Between Antihypertensive Medication Use and Non-cardiovascular Outcomes in Older Men
Agostini JV, Tinetti ME, Han L, Peduzzi P, Foody JM, Concato J. Association Between Antihypertensive Medication Use and Non-cardiovascular Outcomes in Older Men. Journal Of General Internal Medicine 2007, 22: 1661-1667. PMID: 17899299, PMCID: PMC2219823, DOI: 10.1007/s11606-007-0388-9.Peer-Reviewed Original ResearchConceptsNon-cardiovascular outcomesAntihypertensive medication useAntihypertensive medicationsMedication useAdverse effectsOlder menCommunity-living older menVeterans Affairs primary care clinicsEpidemiologic Studies-Depression scoreOlder adultsMultiple antihypertensive medicationsPhysical performancePrimary care clinicsDrug adverse effectsRoutine clinical practiceCES-D scoresHigh cumulative exposureRelated adverse effectsTrail Making BMedication intensityTest Part BHypertensive menCerebrovascular effectsCohort studyBlood pressure