Featured Publications
Use of Medications With Anticholinergic Effect Predicts Clinical Severity of Delirium Symptoms in Older Medical Inpatients
Han L, McCusker J, Cole M, Abrahamowicz M, Primeau F, Elie M. Use of Medications With Anticholinergic Effect Predicts Clinical Severity of Delirium Symptoms in Older Medical Inpatients. JAMA Internal Medicine 2001, 161: 1099-1105. PMID: 11322844, DOI: 10.1001/archinte.161.8.1099.Peer-Reviewed Original ResearchConceptsDelirium severityACH medicationsMedication exposureDelirium symptomsMedical inpatientsInpatients 65 yearsModifiable risk factorsOlder medical inpatientsUse of medicationsPresence of dementiaElderly medical inpatientsMixed linear regression modelsAnticholinergic medicationsACh effectsAnticholinergic effectsMedication usePrevalent deliriumDelirium IndexRisk factorsClinical severityMedicationsDeliriumSymptom severityLongitudinal associationsSeverity
2020
Risk Factors for Disability After Emergency Department Discharge in Older Adults
Nagurney JM, Han L, Leo‐Summers L, Allore HG, Gill TM. Risk Factors for Disability After Emergency Department Discharge in Older Adults. Academic Emergency Medicine 2020, 27: 1270-1278. PMID: 32673434, PMCID: PMC7749835, DOI: 10.1111/acem.14088.Peer-Reviewed Original ResearchConceptsLower extremity weaknessDisability burdenRisk factorsOlder adultsED visitsPhysical frailtyLongitudinal multivariable modelsEmergency department dischargeModifiable risk factorsCommunity-living personsCandidate risk factorsEmergency department experienceED dischargeNonmodifiable factorsMultivariable analysisRisk stratificationFunctional outcomeIndependent associationMultivariable modelOngoing longitudinal studyMonthly interviewsAnalytic sampleFunctional activityAdultsVisits
2004
Modifiable Risk Factors for Nursing Home-Acquired Pneumonia
Quagliarello V, Ginter S, Han L, Van Ness P, Allore H, Tinetti M. Modifiable Risk Factors for Nursing Home-Acquired Pneumonia. Clinical Infectious Diseases 2004, 40: 1-6. PMID: 15614684, DOI: 10.1086/426023.Peer-Reviewed Original ResearchConceptsModifiable risk factorsElderly nursing home residentsInadequate oral careNursing home residentsCox proportional hazards modelCases of pneumoniaRisk factorsProportional hazards modelOral careHome residentsSurveillance periodHazards modelCandidate modifiable risk factorNursing Home-Acquired PneumoniaPneumonia prevention strategiesRisk of pneumoniaPrimary outcomeSwallowing difficultiesIndependent associationAttributable fractionPneumoniaNursing homesPrevention strategiesElderly residentsSame covariates
2001
Environmental Risk Factors for Delirium in Hospitalized Older People
McCusker J, Cole M, Abrahamowicz M, Han L, Podoba J, Ramman‐Haddad L. Environmental Risk Factors for Delirium in Hospitalized Older People. Journal Of The American Geriatrics Society 2001, 49: 1327-1334. PMID: 11890491, DOI: 10.1046/j.1532-5415.2001.49260.x.Peer-Reviewed Original ResearchConceptsEnvironmental risk factorsRisk factorsPhysical restraintDelirium symptomsSeverity scoreHospital unitsObservational prospective clinical studyPrior cognitive impairmentSymptoms of deliriumConfusion Assessment MethodModifiable risk factorsGeneral community hospitalProspective clinical studyPatients age 65Potential environmental risk factorsSymptom severity scoresHospitalized older peopleDelirium severity scoresMedical wardsPatient characteristicsDelirium IndexIntensive careInitial severityCommunity hospitalClinical studies