Featured Publications
Use of Medications With Anticholinergic Effect Predicts Clinical Severity of Delirium Symptoms in Older Medical Inpatients
Han L, McCusker J, Cole M, Abrahamowicz M, Primeau F, Elie M. Use of Medications With Anticholinergic Effect Predicts Clinical Severity of Delirium Symptoms in Older Medical Inpatients. JAMA Internal Medicine 2001, 161: 1099-1105. PMID: 11322844, DOI: 10.1001/archinte.161.8.1099.Peer-Reviewed Original ResearchConceptsDelirium severityACH medicationsMedication exposureDelirium symptomsMedical inpatientsInpatients 65 yearsModifiable risk factorsOlder medical inpatientsUse of medicationsPresence of dementiaElderly medical inpatientsMixed linear regression modelsAnticholinergic medicationsACh effectsAnticholinergic effectsMedication usePrevalent deliriumDelirium IndexRisk factorsClinical severityMedicationsDeliriumSymptom severityLongitudinal associationsSeverity
2006
Recoverable Cognitive Dysfunction at Hospital Admission in Older Persons During Acute Illness
Inouye SK, Zhang Y, Han L, Leo‐Summers L, Jones R, Marcantonio E. Recoverable Cognitive Dysfunction at Hospital Admission in Older Persons During Acute Illness. Journal Of General Internal Medicine 2006, 21: 1276-1281. PMID: 16965558, PMCID: PMC1924736, DOI: 10.1111/j.1525-1497.2006.00613.x.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAcute DiseaseAgedAged, 80 and overCognition DisordersCohort StudiesDeliriumDementiaEducational StatusFemaleHospitalizationHumansIncidenceMalePredictive Value of TestsProspective StudiesPsychiatric Status Rating ScalesRecovery of FunctionSeverity of Illness IndexConceptsMini-Mental State ExaminationCognitive dysfunctionAcute illnessOlder personsProspective cohort studyAdjusted odds ratioHigher illness severityPotential clinical implicationsMajority of casesHigher educational levelCohort studyHospital admissionPrimary outcomeIllness severityMultivariable analysisConsecutive admissionsOdds ratioAcademic hospitalFunctional impairmentMMSE scoresState ExaminationDeliriumMMSE impairmentDysfunctionPatients
2003
The Course of Delirium in Older Medical Inpatients
McCusker J, Cole M, Dendukuri N, Han L, Belzile É. The Course of Delirium in Older Medical Inpatients. Journal Of General Internal Medicine 2003, 18: 696-704. PMID: 12950477, PMCID: PMC1494920, DOI: 10.1046/j.1525-1497.2003.20602.x.Peer-Reviewed Original ResearchConceptsOutcome of deliriumClinical courseMedical inpatientsCourse of deliriumHospital clinical courseProspective cohort studyOlder medical inpatientsTime of diagnosisSeverity of illnessSubgroup of patientsNursing home residencePost-discharge outcomesAcute care hospitalsRole of dementiaHospital courseInitial hospitalizationCohort studyPersistent symptomsCare hospitalHospital recoveryMedical wardsFunctional outcomeAdmission levelsDaily livingDeliriumThe Prognostic Significance of Subsyndromal Delirium in Elderly Medical Inpatients
Cole M, McCusker J, Dendukuri N, Han L. The Prognostic Significance of Subsyndromal Delirium in Elderly Medical Inpatients. Journal Of The American Geriatrics Society 2003, 51: 754-760. PMID: 12757560, DOI: 10.1046/j.1365-2389.2003.51255.x.Peer-Reviewed Original ResearchConceptsElderly medical inpatientsMedical inpatientsPrognostic significanceLonger acute care hospital staysAcute care hospital stayCore symptomsAcute care hospitalsPostdischarge mortalityRevised (DSM-III-R) criteriaHospital stayCohort studyCare hospitalRisk factorsSubsyndromal deliriumDementia statusImportant syndromeDeliriumPhysiological severityMore symptomsAdmissionMental disordersSymptomsPatientsFirst weekInpatients
2002
Symptoms of Delirium Among Elderly Medical Inpatients With or Without Dementia
Cole MG, McCusker J, Dendukuri N, Han L. Symptoms of Delirium Among Elderly Medical Inpatients With or Without Dementia. Journal Of Neuropsychiatry 2002, 14: 167-175. PMID: 11983791, DOI: 10.1176/jnp.14.2.167.Peer-Reviewed Original Research