2020
Development and validation of multivariable mortality risk-prediction models in older people undergoing an interRAI home-care assessment (RiskOP)
Pickering JW, Abey-Nesbit R, Allore H, Jamieson H. Development and validation of multivariable mortality risk-prediction models in older people undergoing an interRAI home-care assessment (RiskOP). EClinicalMedicine 2020, 29: 100614. PMID: 33437945, PMCID: PMC7788437, DOI: 10.1016/j.eclinm.2020.100614.Peer-Reviewed Original ResearchRisk prediction modelOlder peopleInterRAI home care assessmentMortality risk prediction modelMultivariable logistic regression modelResident Assessment Instrument-Home Care (RAI-HC) assessmentOne-year survivalHome care assessmentFull multivariable modelHealth Research CouncilLogistic regression modelsTargeted careStudy cohortMultivariable modelCare assessmentMortality riskClinical decisionHealthcare resource allocationOne-yearOlder adultsLife expectancy
2018
A functional macrophage migration inhibitory factor promoter polymorphism is associated with reduced diffusing capacity
Zhang C, Ramsey C, Berical A, Yu L, Leng L, McGinnis K, Song Y, Michael H, McCormack M, Allore H, Morris A, Crothers K, Bucala R, Lee P, Sauler M. A functional macrophage migration inhibitory factor promoter polymorphism is associated with reduced diffusing capacity. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2018, 316: l400-l405. PMID: 30520689, PMCID: PMC6397351, DOI: 10.1152/ajplung.00439.2018.Peer-Reviewed Original ResearchConceptsMacrophage migration inhibitory factorChronic obstructive pulmonary diseaseMIF -794 CATTAbnormal diffusion capacityCigarette smoke exposureSmoke exposureAssociation of MIFDiffusion capacityMacrophage migration inhibitory factor (MIF) promoter polymorphismsPathogenesis of COPDChronic cigarette smoke exposureMultivariable logistic regression modelModifiable risk factorsObstructive pulmonary diseaseMigration inhibitory factorCross-sectional analysisLogistic regression modelsCommon genetic polymorphismsInnate immune genesAirflow obstructionMIF expressionCOPD severityPulmonary diseaseMIF allelesRisk factors