2024
Supervised Disulfiram Should Be Considered First-line Treatment for Alcohol Use Disorder
Holt S. Supervised Disulfiram Should Be Considered First-line Treatment for Alcohol Use Disorder. Journal Of Addiction Medicine 2024, 18: 614-616. PMID: 39150091, DOI: 10.1097/adm.0000000000001345.Peer-Reviewed Original ResearchConceptsAlcohol use disorderSupervised disulfiramUse disorderAlcohol use disorder treatmentPrevalence of alcohol use disordersFDA-approved medicationsRandomized controlled trialsFirst-line interventionBehavioral interventionsDouble-blind randomized controlled trialApproved medicationsDisulfiramOpen-label randomized controlled trialSecond-line optionFirst-line treatmentNational treatment guidelinesDisordersTherapeutic resourcesEfficacy dataMedicationTreatment guidelinesAddictionControlled trialsInterventionPatient preferences
2019
Unhealthy Alcohol Use
Holt S, Donroe J. Unhealthy Alcohol Use. DeckerMed Psychiatry 2019 DOI: 10.2310/psych.13106.Peer-Reviewed Original Research
2018
Pharmacotherapy for Alcohol Use Disorder
Holt SR, Tobin DG. Pharmacotherapy for Alcohol Use Disorder. Medical Clinics Of North America 2018, 102: 653-666. PMID: 29933821, DOI: 10.1016/j.mcna.2018.02.008.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAlcohol use disorderUse disordersNondrug therapiesUndertreated diseaseTreatment optionsPharmacotherapeutic agentsDrug interactionsTreatment goalsUS FoodDrug AdministrationSpecific patientDrug availabilityDisordersPatientsCounseling strategiesComorbiditiesMedicationsPharmacotherapyOptionsTherapyDiseaseAdministrationCare
2016
Unhealthy Alcohol Use
Holt S, Tetrault J. Unhealthy Alcohol Use. Clinics In Liver Disease 2016, 20: 429-444. PMID: 27373607, DOI: 10.1016/j.cld.2016.02.003.Peer-Reviewed Original ResearchConceptsUnhealthy alcohol useAlcohol useSymptom-triggered approachAlcohol use disorderAlcohol withdrawalAppropriate treatmentRoutine screeningPatient motivationUse disordersBrief interventionHazardous drinkingBehavioral therapyHeavy drinkingPatientsRobust dataBehavioral changesDrinkingTwelve-step programsMedicationsTherapyBenzodiazepinesAbstinence