Sarah E. Fitzpatrick
she/her/hers
About
Research
Publications
2026
Transcriptomic and phenotypic convergence of neurodevelopmental disorder risk genes in vitro and in vivo
Fernandez Garcia M, Retallick-Townsley K, Pruitt A, Davidson E, Balafkan N, Warrell J, Huang T, Kibowen A, Chu Z, Dai Y, Fitzpatrick S, Meng R, Sen A, Cohen S, Livoti O, Khan S, Becker C, Luiz Teles e Silva A, Liu J, Dossou G, Cheung J, Liu S, Ghorbani S, Deans P, DeCiucis M, Emani P, Gao H, Shen H, Gerstein M, Wang Z, Huckins L, Hoffman E, Brennand K. Transcriptomic and phenotypic convergence of neurodevelopmental disorder risk genes in vitro and in vivo. Nature Neuroscience 2026, 29: 1079-1094. PMID: 42032432, PMCID: PMC13156037, DOI: 10.1038/s41593-026-02247-7.Peer-Reviewed Original ResearchPharmaco-behavioral profiling identifies suppressors of autism gene–associated phenotypes in zebrafish
Jamadagni P, Dai Y, Liu Y, Mendes H, Pruitt A, Khan S, Yang L, Huang T, Huang X, Deans P, Balafkan N, Zhao D, Xu G, Liu Y, Li N, Wu W, Fitzpatrick S, Neelakantan U, Chen T, Szialta C, Jin D, Lacadie C, Umlauf S, Papademetris X, Surovtseva Y, Brennand K, Wang Z, Hoffman E. Pharmaco-behavioral profiling identifies suppressors of autism gene–associated phenotypes in zebrafish. Proceedings Of The National Academy Of Sciences Of The United States Of America 2026, 123: e2518846123. PMID: 41838920, PMCID: PMC13012064, DOI: 10.1073/pnas.2518846123.Peer-Reviewed Original Research
2024
Review: Child Psychiatry in the Era of Genomics: The Promise of Translational Genetics Research for the Clinic
Fitzpatrick S, Antony I, Nurmi E, Fernandez T, Chung W, Brownstein C, Gonzalez-Heydrich J, Gur R, Merner A, Lázaro-Muñoz G, State M, Simon K, Hoffman E. Review: Child Psychiatry in the Era of Genomics: The Promise of Translational Genetics Research for the Clinic. JAACAP Open 2024, 3: 157-170. PMID: 40520982, PMCID: PMC12166933, DOI: 10.1016/j.jaacop.2024.06.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2023
High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways
Mendes H, Neelakantan U, Liu Y, Fitzpatrick S, Chen T, Wu W, Pruitt A, Jin D, Jamadagni P, Carlson M, Lacadie C, Enriquez K, Li N, Zhao D, Ijaz S, Sakai C, Szi C, Rooney B, Ghosh M, Nwabudike I, Gorodezky A, Chowdhury S, Zaheer M, McLaughlin S, Fernandez J, Wu J, Eilbott J, Vander Wyk B, Rihel J, Papademetris X, Wang Z, Hoffman E. High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways. Cell Reports 2023, 42: 112243. PMID: 36933215, PMCID: PMC10277173, DOI: 10.1016/j.celrep.2023.112243.Peer-Reviewed Original Research
2021
Medical Student Patient Outreach to Ensure Continuity of Care During the COVID-19 Pandemic
Belzer A, Yeagle EM, Kohlenberg LK, Solberg M, Gudbranson E, Budge M, Batchelor HM, Fitzpatrick SE, Zhao A, Armengol VD, Hassan SF, Shum M, Bia M, Bia F, Desai NR, Kahn PA. Medical Student Patient Outreach to Ensure Continuity of Care During the COVID-19 Pandemic. Telemedicine Reports 2021, 2: 56-63. PMID: 35720754, PMCID: PMC9049823, DOI: 10.1089/tmr.2020.0030.Peer-Reviewed Original Research
2019
Pediatric Quality of Life Inventory (PedsQL) in Fragile X Syndrome
Fitzpatrick S, Schmitt L, Adams R, Pedapati E, Wink L, Shaffer R, Sage J, Weber J, Dominick K, Erickson C. Pediatric Quality of Life Inventory (PedsQL) in Fragile X Syndrome. Journal Of Autism And Developmental Disorders 2019, 50: 1056-1063. PMID: 31728808, PMCID: PMC7232688, DOI: 10.1007/s10803-019-04292-7.Peer-Reviewed Original Research
2017
Challenges in Conducting Clinical Trials for Pharmacotherapies in Fragile X Syndrome: Lessons Learned
Harkins C, Dominick K, Wink L, Pedapati E, Shaffer R, Fitzpatrick S, Davenport M, Sweeney J, Erickson C. Challenges in Conducting Clinical Trials for Pharmacotherapies in Fragile X Syndrome: Lessons Learned. Pharmaceutical Medicine 2017, 31: 235-244. DOI: 10.1007/s40290-017-0199-1.Peer-Reviewed Original ResearchFragile X targeted pharmacotherapy: lessons learned and future directions
Erickson C, Davenport M, Schaefer T, Wink L, Pedapati E, Sweeney J, Fitzpatrick S, Brown W, Budimirovic D, Hagerman R, Hessl D, Kaufmann W, Berry-Kravis E. Fragile X targeted pharmacotherapy: lessons learned and future directions. Journal Of Neurodevelopmental Disorders 2017, 9: 7. PMID: 28616096, PMCID: PMC5467059, DOI: 10.1186/s11689-017-9186-9.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2016
Premutation-Associated Disorders in Childhood and Adulthood
Hagerman R, Wheeler A, Fitzpatrick S, Hunter J. Premutation-Associated Disorders in Childhood and Adulthood. 2016, 241-262. DOI: 10.1007/978-3-319-33898-9_12.ChaptersA Randomized, Double-Blind, Placebo-Controlled Trial of Low-Dose Sertraline in Young Children With Fragile X Syndrome
Greiss Hess L, Fitzpatrick S, Nguyen D, Chen Y, Gaul K, Schneider A, Lemons Chitwood K, Eldeeb M, Polussa J, Hessl D, Rivera S, Hagerman R. A Randomized, Double-Blind, Placebo-Controlled Trial of Low-Dose Sertraline in Young Children With Fragile X Syndrome. Journal Of Developmental And Behavioral Pediatrics 2016, 37: 619-628. PMID: 27560971, PMCID: PMC5039060, DOI: 10.1097/dbp.0000000000000334.Peer-Reviewed Original Research
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Locations
Hoffman Lab, Room I-269
Lab
Sterling Hall of Medicine, I-Wing
333 Cedar Street
New Haven, CT 06510