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INFORMATION FOR

Kristopher Kahle, MD, PhD

Assistant Professor Adjunct
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Additional Titles

Pediatrics, and Cellular and Molecular Physiology

Director, Neonatal and Congenital Anomaly Neurosurgery

Contact Info

kristopher.kahle@yale.edu

Neurosurgery

789 Howard Avenue, Tompkins 4

New Haven, CT 06520

United States

About

Titles

Assistant Professor Adjunct

Pediatrics, and Cellular and Molecular Physiology; Director, Neonatal and Congenital Anomaly Neurosurgery

Biography

Kristopher T. Kahle, M.D., Ph.D., is an Adjunct Professor of Neurosurgery and Pediatrics and Cellular and Molecular Physiology at Yale School of Medicine, and Director of Neonatal and Congenital Anomaly Neurosurgery in the Division of Pediatric Neurosurgery. He completed his MD and PhD degrees at the Yale School of Medicine under the mentorship of Richard Lifton, and neurosurgical residency at the Massachusetts General Hospital. After residency, Dr. Kahle completed his pediatric neurosurgery fellowship at Boston Children’s Hospital and was Instructor at Harvard Medical School. Dr. Kahle completed a postdoctoral research fellowship with Stephen Elledge and David Clapham at Harvard University. Dr. Kahle’s primary clinical practice includes disorders of neurodevelopment (hydrocephalus, arachnoid cysts, congenital vascular malformations, chiari malformations, spina bifida, and tethered spinal cord) and tumors of the pediatric brain and spinal cord. Dr. Kahle trained in neuroendoscopy, including third ventriculostomy and choroid plexus coagulation, with Dr. Benjamin Warf at Harvard. Dr. Kahle is an attending physician at Yale New Haven Hospital and the Yale New Haven Children’s Hospital. Dr. Kahle’s research is devoted to identifying the genes and pathways that regulate ion and water homeostasis in the developing nervous system, and how genetically-encoded or maladaptive changes in these processes contribute to the cellular, circuit, and behavioral abnormalities in neurodevelopmental disorders and in the traumatized brain. He also uses molecular genetic tools such as whole exome and genome sequencing to discover the molecular determinants of neurodevelopmental diseases, such as congenital hydrocephalus. The goal of his work is to translate advances in basic science into novel therapeutic strategies for pediatric neurosurgical diseases.

Appointments

Other Departments & Organizations

Education & Training

Pediatric Neurosurgery Fellowship
Boston Children's Hospital (2015)
Post-doctoral Research Fellow
Harvard Medical School (2015)
Neurosurgery Residency
Massachusetts General Hospital (2014)
MD
Yale School of Medicine (2007)
PhD
Yale University, Cellular and Molecular Physiology (2007)

Research

Research at a Glance

Yale Co-Authors

Frequent collaborators of Kristopher Kahle's published research.

Publications

2024

See All Publications

Clinical Trials

Current Trials

Get In Touch

Contacts

Email
Appointment Number
Mailing Address

Neurosurgery

789 Howard Avenue, Tompkins 4

New Haven, CT 06520

United States

Administrative Support