Research & Publications
Dr. Faustino studies treatment strategies that could improve the outcomes of critically ill children. He is currently focused on the prevention of blood clots in these children. He conducts observational and interventional studies to understand how blood clots form in children.
Specialized Terms: venous thrombosis; thromboembolism; anticoagulation; hemostasis; thrombin generation; platelet; clinical trial; biomarker; risk prediction model; critical care; child
Extensive Research Description
Dr. Faustino is a patient-oriented researcher who focuses on improving the outcomes of critically ill children. His research is focused on the prevention of venous thrombosis and its complications in children. He is the Principal Investigator of the Pathobiology, Epidemiology and Interventions against Thrombotic and Hemostatic Outcomes (PEITHO) Program. The goals of the PEITHO Program are (1) to conduct multi center observational studies that will inform the design and execution of interventional studies on venous thrombosis in children, (2) to conduct multi center randomized clinical trials on the prevention of venous thrombosis in children that will inform clinical practice, and (3) to leverage observational and interventional studies to understand the pathobiology of venous thrombosis in children.
Dr. Faustino is primarily investigating catheter-related thrombosis because the use of central venous catheters is the most common cause of venous thrombosis in children. He has conducted observational studies on the epidemiology of catheter-related thrombosis in critically ill children, completed surveys on thromboprophylaxis in pediatric intensive care units, identified potential biomarkers for catheter-related thrombosis and established collaborations with other researchers invested in the prevention of venous thrombosis. He recently completed a randomized clinical trial on early thromboprophylaxis against catheter-related thrombosis in critically ill children.
Dr. Faustino's ongoing studies include:
1. Age-dependent efficacy of enoxaparin against catheter-related thrombosis in critically ill children. The goal of these studies is to investigate the differential efficacy of enoxaparin between critically ill infants and older children against catheter-related thrombosis.
2. Role of platelets in catheter-related thrombosis in infants. The goal of these studies is to understand the role of platelets in the development of catheter-related thrombosis in infants.
3. Venous thrombosis in children at high risk of bleeding. The goal of these studies is to identify effective strategies against venous thrombosis in surgical or seriously injured children.
4. Venous thrombosis in critically ill adolescents. The goal of these studies is to identify the optimal strategy to prevent venous thrombosis in critically ill adolescents.
Anticoagulants; Blood Platelets; Child; Critical Care; Hemostasis; Pediatrics; Thrombin; Thromboembolism; Biomarkers; Clinical Trial; Venous Thrombosis
- Pharmacologic restraint during ED mental health visitsFaustino E. Pharmacologic restraint during ED mental health visits The Journal Of Pediatrics 2021, 236: 1-3. DOI: 10.1016/j.jpeds.2021.07.028.
- Design and Development of A-vent: A Low-Cost Ventilator with Cost-Effective Mobile Cloud Caching and Embedded Machine LearningCabacungan P, Oppus C, Cabacungan N, Mamaradlo J, Santiago P, Mercado N, Faustino E, Tangonan G. Design and Development of A-vent: A Low-Cost Ventilator with Cost-Effective Mobile Cloud Caching and Embedded Machine Learning 2021, 00: 1-8. DOI: 10.1109/tensymp52854.2021.9550920.
- 623: Risk Assessment Scoring for Venous Thromboembolism in Critically Ill AdolescentsGupta A, Faustino E. 623: Risk Assessment Scoring for Venous Thromboembolism in Critically Ill Adolescents Critical Care Medicine 2020, 49: 305-305. DOI: 10.1097/01.ccm.0000728380.57915.da.
- Intravenous magnesium for asthma exacerbationFaustino E. Intravenous magnesium for asthma exacerbation The Journal Of Pediatrics 2020, 220: 1-3. DOI: 10.1016/j.jpeds.2020.03.045.
- 308Faustino E, Hirshberg E, Biagas K, Asaro L, Pinto N, Srinivasan V, Bagdure D, Wypij D, Steil G, Coughlin-Wells K, Nadkarni V, Agus M. 308 Critical Care Medicine 2019, 47: 135. DOI: 10.1097/01.ccm.0000551062.09983.f9.
- 413Srinivasan V, Hasbani N, Asaro L, Mehta N, Irving S, Kandil S, Allen C, Typpo K, Cvijanovich N, Faustino E, Wypij D, Agus M, Nadkarni V. 413 Critical Care Medicine 2018, 46: 190. DOI: 10.1097/01.ccm.0000528431.32594.04.
- 511Faustino E, Shabanova V. 511 Critical Care Medicine 2016, 44: 204. DOI: 10.1097/01.ccm.0000509189.52681.88.
- 522White L, Fredericks R, Mannarino C, Janofsky S, Faustino E. 522 Critical Care Medicine 2016, 44: 207. DOI: 10.1097/01.ccm.0000509200.98423.76.
- 602Faustino E, Li S, Pinto M, Trakas E, Gertz S, Miksa M, Silva C. 602 Critical Care Medicine 2016, 44: 227. DOI: 10.1097/01.ccm.0000509279.64732.0c.
- Thromboprophylaxis in critically ill children in Spain and PortugalNúñez A, Fonte M, Faustino E, del estudio multicéntrico internacional PROTRACT E. Thromboprophylaxis in critically ill children in Spain and Portugal Anales De Pediatría (English Edition) 2015, 82: 144-151. DOI: 10.1016/j.anpede.2014.05.002.
- Assessing the benefits and risks of tight glycemic control in critically ill childrenFaustino E, Kandil S. Assessing the benefits and risks of tight glycemic control in critically ill children Pediatric Health Medicine And Therapeutics 2014, Volume 5: 93-98. DOI: 10.2147/phmt.s50410.
- Hyperglycemia, Dysglycemia and Glycemic Control in Pediatric Critical CareAgus M, Faustino E, Rigby M. Hyperglycemia, Dysglycemia and Glycemic Control in Pediatric Critical Care 2014, 93-101. DOI: 10.1007/978-1-4471-6416-6_8.
- ABSTRACT 114Faustino E, Li S, Pinto M, Polikoff L, Tala J, Silva C, Shapiro E. ABSTRACT 114 Pediatric Critical Care Medicine 2014, 15: 31. DOI: 10.1097/01.pcc.0000448840.20300.dd.
- ReplyFaustino E, Apkon M. Reply The Journal Of Pediatrics 2006, 148: 847-848. DOI: 10.1016/j.jpeds.2006.01.015.