Sonia Caprio, MD
Professor of Pediatrics (Endocrinology)
Research & Publications
Biography
News
Research Summary
Dr. Sonia Caprio researches the pathophysiology of metabolic defects of juvenile obesity, including metabolic predictors and markers of childhood obesity. Her research includes the pathophysiology of Type 2 Diabetes in youth, including uncovering the metabolic phenotype of pre-diabetes in youth. She is the Principle Investigator of an NIH-funded multicenter study of the treatment of T2DM in youth.
Specialized Terms: Pathophysiology of Insulin Resistance in Children; Metabolic Complications of Childhood Obesity; Pathophysiology of Prediabetes in Obese Youth
Coauthors
Research Interests
Endocrinology; Insulin; Obesity; Pediatrics; Prediabetic State; Pediatric Obesity
Selected Publications
- Leptin Is Associated With Exaggerated Brain Reward and Emotion Responses to Food Images in Adolescent ObesityJastreboff AM, Lacadie C, Seo D, Kubat J, Van Name MA, Giannini C, Savoye M, Constable RT, Sherwin RS, Caprio S, Sinha R. Leptin Is Associated With Exaggerated Brain Reward and Emotion Responses to Food Images in Adolescent Obesity. Diabetes Care 2014, 37: 3061-3068. PMID: 25139883, PMCID: PMC4207200, DOI: 10.2337/dc14-0525.
- A low disposition index in adolescent offspring of mothers with gestational diabetes: a risk marker for the development of impaired glucose tolerance in youthHolder T, Giannini C, Santoro N, Pierpont B, Shaw M, Duran E, Caprio S, Weiss R. A low disposition index in adolescent offspring of mothers with gestational diabetes: a risk marker for the development of impaired glucose tolerance in youth. Diabetologia 2014, 57: 2413-2420. PMID: 25168408, DOI: 10.1007/s00125-014-3345-2.
- The development of type 2 diabetes in the obese adolescents: a growing challenge.Caprio S. The development of type 2 diabetes in the obese adolescents: a growing challenge. Clinical Biochemistry 2014, 47: 721. PMID: 24854690, DOI: 10.1016/j.clinbiochem.2014.05.027.
Clinical Trials
| Conditions | Study Title |
|---|---|
| Children's Health; Diseases of the Digestive System - Liver | The Role of Hepatic De Novo Lipogenesis (DNL) in the Pathogenesis of Hepatic Steatosis |
| Children's Health; Diseases of the Endocrine System; Immune System | Study to investigate adipocyte cell and lipid turnover in obese adolescents |
| Children's Health; Diabetes Mellitus - Type 2; Diseases of the Cardiovascular System; Diseases of the Endocrine System; Genetics - Pediatric; Obesity & Weight Control | Prevalence of Carbohydrate Intolerance in Lean and Obese Children |
| Obesity & Weight Control | Preventing Obesity in Preterm Infants |
| Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease |