Louise Wang, MD, MSCE
Assistant Professor
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Research Summary
Dr. Wang is a physician-scientist at Yale School of Medicine whose research focuses on early detection of pancreatic cancer at the intersection of bioinformatics, genetics, and epidemiology. The goal of her research program is to improve early detection of pancreatic cancer by integrating classic epidemiological approaches with human genetics and genomics using electronic health record-linked biorepositories. She is currently funded by a VA Career Development Award-2. Dr. Wang is also a staff gastroenterologist in the VA Connecticut Healthcare system.
Research Interests
Epidemiology; Gastroenterology; Genetics; Internal Medicine; Natural Language Processing; Veterans; Carcinoma, Pancreatic Ductal; Informatics; Early Detection of Cancer; Machine Learning
Selected Publications
- Development and validation of case-finding algorithms to identify acute pancreatitis in the Veterans Health Administration.Wang LL, Dobkin J, Salgado S, Kaplan DE, Yang YX. Development and validation of case-finding algorithms to identify acute pancreatitis in the Veterans Health Administration. Pharmacoepidemiol Drug Saf 2022, 31: 1294-1299. PMID: 36222554, DOI: 10.1002/pds.5549.
- Summary of the experiences, knowledge, medical management, and family communication of monoallelic MUTYH carriersMcKenna D, Sanchez P, Powers J, Brower J, Wang L, Mueller R, Symecko H, Hamilton J, Wildman T, Domchek S, Couch F, Garber J, Offit K, Robson M, Katona B. Summary of the experiences, knowledge, medical management, and family communication of monoallelic MUTYH carriers. Journal Of Genetic Counseling 2022, 32: 342-350. PMID: 36245263, DOI: 10.1002/jgc4.1641.
- Cost-Effectiveness of a Risk-Tailored Pancreatic Cancer Early Detection Strategy Among Patients With New-Onset Diabetes.Wang L, Scott FI, Boursi B, Reiss KA, Williams S, Glick H, Yang YX. Cost-Effectiveness of a Risk-Tailored Pancreatic Cancer Early Detection Strategy Among Patients With New-Onset Diabetes. Clinical Gastroenterology And Hepatology : The Official Clinical Practice Journal Of The American Gastroenterological Association 2022, 20: 1997-2004.e7. PMID: 34737092, DOI: 10.1016/j.cgh.2021.10.037.
- Efficacy of Recombinant Zoster Vaccine in Patients With Inflammatory Bowel Disease.Khan N, Wang L, Trivedi C, Pernes T, Patel M, Xie D, Yang YX. Efficacy of Recombinant Zoster Vaccine in Patients With Inflammatory Bowel Disease. Clinical Gastroenterology And Hepatology : The Official Clinical Practice Journal Of The American Gastroenterological Association 2022, 20: 1570-1578.e1. PMID: 34274513, DOI: 10.1016/j.cgh.2021.07.023.
- Performance of polygenic risk scores for cancer prediction in a racially diverse academic biobank.Wang L, Desai H, Verma SS, Le A, Hausler R, Verma A, Judy R, Doucette A, Gabriel PE, Nathanson KL, Damrauer SM, Mowery DL, Ritchie MD, Kember RL, Maxwell KN. Performance of polygenic risk scores for cancer prediction in a racially diverse academic biobank. Genetics In Medicine : Official Journal Of The American College Of Medical Genetics 2022, 24: 601-609. PMID: 34906489, DOI: 10.1016/j.gim.2021.10.015.
- Reaching beyond family history as inclusion criteria for pancreatic cancer surveillance in high-risk populations.Wang L, Domchek SM, Kochman ML, Katona BW. Reaching beyond family history as inclusion criteria for pancreatic cancer surveillance in high-risk populations. Genes & Cancer 2022, 13: 49-51. PMID: 36051752, PMCID: PMC9423661, DOI: 10.18632/genesandcancer.223.
- Associations of sociodemographic and clinical factors with gastrointestinal cancer risk assessment appointment completion.Ebrahimzadeh JE, Long JM, Wang L, Nathanson JT, Siddique SM, Rustgi AK, Goldberg DS, Katona BW. Associations of sociodemographic and clinical factors with gastrointestinal cancer risk assessment appointment completion. Journal Of Genetic Counseling 2020, 29: 616-624. PMID: 32227561, PMCID: PMC7415544, DOI: 10.1002/jgc4.1254.
- Low Rates of Gastrointestinal and Non-Gastrointestinal Complications for Screening or Surveillance Colonoscopies in a Population-Based Study.Wang L, Mannalithara A, Singh G, Ladabaum U. Low Rates of Gastrointestinal and Non-Gastrointestinal Complications for Screening or Surveillance Colonoscopies in a Population-Based Study. Gastroenterology 2018, 154: 540-555.e8. PMID: 29031502, DOI: 10.1053/j.gastro.2017.10.006.
- Health outcomes in US children with abdominal pain at major emergency departments associated with race and socioeconomic status.Wang L, Haberland C, Thurm C, Bhattacharya J, Park KT. Health outcomes in US children with abdominal pain at major emergency departments associated with race and socioeconomic status. PloS One 2015, 10: e0132758. PMID: 26267816, PMCID: PMC4534408, DOI: 10.1371/journal.pone.0132758.
- Small increases to employer premiums could shift millions of people to the exchanges and add billions to federal outlays.Austin DR, Luan A, Wang LL, Bhattacharya J. Small increases to employer premiums could shift millions of people to the exchanges and add billions to federal outlays. Health Affairs (Project Hope) 2013, 32: 1531-7. PMID: 24019356, DOI: 10.1377/hlthaff.2013.0522.
- Cost-effectiveness of universal serologic screening to prevent nontraumatic hip and vertebral fractures in patients with celiac disease.Park KT, Tsai R, Wang L, Khavari N, Bachrach L, Bass D. Cost-effectiveness of universal serologic screening to prevent nontraumatic hip and vertebral fractures in patients with celiac disease. Clinical Gastroenterology And Hepatology : The Official Clinical Practice Journal Of The American Gastroenterological Association 2013, 11: 645-53. PMID: 23357490, PMCID: PMC3655158, DOI: 10.1016/j.cgh.2012.12.037.
- LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms.King CE, Wang L, Winograd R, Madison BB, Mongroo PS, Johnstone CN, Rustgi AK. LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms. Oncogene 2011, 30: 4185-93. PMID: 21625210, PMCID: PMC3165068, DOI: 10.1038/onc.2011.131.
- Evidence of sexual shape dimorphism in Viviparus (Gastropoda: Viviparidae). Minton RL, Wang LL. Evidence of sexual shape dimorphism in Viviparus (Gastropoda: Viviparidae). Journal of Molluscan Studies 2011;77:315-317.