Linda Niccolai, PhD
Associate Dean for Academic Affairs and Professor of Epidemiology (Microbial Diseases); Affiliated Faculty, Yale Institute for Global Health; Director, HPV Working Group at Yale; Director, CT Emerging Infections Program at Yale, Epidemiology of Microbial Diseases
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Research Summary
Professor Niccolai is an epidemiologist whose research is primarily focused on sexually transmitted infections (STI), including HIV. Her main area of interest is in behavioral aspects of HIV/STI prevention. Currently, Professor Niccolai is involved in several areas of research. Her main area of research is studying uptake and impact of human papillomavirus vaccines with an emphasis on addressing health disparities. She is the Project Director of a surveillance program to monitor impact of the human papillomavirus vaccine with the Connecticut Emerging Infections Program. She is also the Principal Investigator of a mixed-methods study to identify barriers to HPV vaccination among low-income minority populations. She is currently working to identify opportunities to increase uptake in CT.
Specialized Terms: Sexually transmitted infections; Human papillomavirus vaccine; HIV; Epidemiologic methods; Qualitative research
Extensive Research Description
Linda Niccolai is a professor in the Department of Epidemiology of Microbial Diseases at the Yale School of Public Health. She is Co-director of the Connecticut Emerging Infections Program at Yale and Director of the Development Core for Yale School of Public Health’s Center for Interdisciplinary Research on AIDS. Her research focuses on sexually transmitted infections, including HPV and HIV. Dr. Niccolai is the principal investigator of project to monitor vaccine impact for human papillomavirus (funded by CDC) and also PI of an NIH-funded mixed methods study to assess barriers to uptake of HPV vaccine.
Linda Niccolai received her Sc.M. at Harvard School of Public Health and her Ph.D. at Tulane University. She is the recipient of Connecticut Infectious Disease Society Thorton Award for Best Poster Presentation in Clinical Research in Infectious Disease and Award for Excellence in Teaching at YSPH.
- Monitoring Impact of Human Papillomavirus Vaccine in Connecticut
- Identifying and Quantifying Barriers to Uptake of HPV vaccine
- Feasibility of a school-based intervention for HPV vaccination
- Increasing HPV vaccination coverage among adolescents in Connecticut
- Social determinants of HIV risk
Coauthors
Research Interests
Epidemiologic Methods; Epidemiology; HIV; Sexually Transmitted Diseases; Vaccines; Communicable Diseases, Emerging; Qualitative Research; Human papillomavirus 11
Public Health Interests
Cancer; Community Health; Environmental Health; Epidemiology Methods; GIS/Disease Mapping; HIV/AIDS; Infectious Diseases; Maternal & Child Health; Community Engagement; Sexually-Transmitted Infections; Vaccines; Child/Adolescent Health; Health Equity, Disparities, Social Determinants and Justice; COVID-19
Selected Publications
- A review of data systems for assessing the impact of HPV vaccination in selected high-income countriesWang W, Kothari S, Khoury H, Niccolai L, Garland S, Sundström K, de Pouvourville G, Bonanni P, Chen Y, Franco E. A review of data systems for assessing the impact of HPV vaccination in selected high-income countries Expert Review Of Vaccines 2023, 22: 161-179. PMID: 36576068, DOI: 10.1080/14760584.2023.2162505.
- Computable Clinical Phenotyping of Postacute Sequelae of COVID-19 in Pediatrics Using Real-World Data.Fashina T, Miller C, Paintsil E, Niccolai L, Brandt C, Oliveira C. Computable Clinical Phenotyping of Postacute Sequelae of COVID-19 in Pediatrics Using Real-World Data. Journal Of The Pediatric Infectious Diseases Society 2022, 12: 113-116. PMID: 36548966, PMCID: PMC9969330, DOI: 10.1093/jpids/piac132.
- Messaging of Different Disease Outcomes for Human Papillomavirus Vaccination: A Systematic ReviewNiccolai L, Johnson N, Torres A, Sullivan E, Hansen C. Messaging of Different Disease Outcomes for Human Papillomavirus Vaccination: A Systematic Review Journal Of Adolescent Health 2022, 72: 334-343. PMID: 36529616, DOI: 10.1016/j.jadohealth.2022.10.018.
- “The Squeaky Wheel Gets the Grease”: Rental Assistance Applicants’ Quests for a Rationed and Scarce ResourceKeene D, Rosenberg A, Schlesinger P, Whittaker S, Niccolai L, Blankenship K. “The Squeaky Wheel Gets the Grease”: Rental Assistance Applicants’ Quests for a Rationed and Scarce Resource Social Problems 2021 DOI: 10.1093/socpro/spab035.
- "The Squeaky Wheel Gets the Grease": Rental Assistance Applicants' Quests for a Rationed and Scarce Resource.Keene D, Rosenberg A, Schlesinger P, Whittaker S, Niccolai L, Blankenship K. "The Squeaky Wheel Gets the Grease": Rental Assistance Applicants' Quests for a Rationed and Scarce Resource. Social Problems 2021, 70: 203-218. PMID: 36798516, PMCID: PMC9928171, DOI: 10.1093/socpro/spab035.
- A Multi Region Analysis of Shale Drilling Activity and Rates of Sexually Transmitted Infections in the United StatesJohnson N, Warren J, Elliott E, Niccolai L, Deziel N. A Multi Region Analysis of Shale Drilling Activity and Rates of Sexually Transmitted Infections in the United States ISEE Conference Abstracts 2020, 2020 DOI: 10.1289/isee.2020.virtual.p-1089.
- Physician and patient prediction of adherence to antiretroviral therapy in HIV positive people in Saint-Petersburg, RussiaVetrova M, Aleksandrova O, Paschenko A, Toropov S, Rassokhin V, Abyshev R, Levina O, Niccolai L, Heimer R. Physician and patient prediction of adherence to antiretroviral therapy in HIV positive people in Saint-Petersburg, Russia AIDS Care 2020, 33: 473-477. PMID: 32148065, DOI: 10.1080/09540121.2020.1738005.
- Introduction to Immunology, Epidemiology, and ImmunoepidemiologyNiccolai L, Ruddle N, Krause P. Introduction to Immunology, Epidemiology, and Immunoepidemiology 2019, 3-17. DOI: 10.1007/978-3-030-25553-4_1.
- 962. Trends in Cervical Pre-cancers by Race and Ethnicity During the Human Papillomavirus Vaccine Era, HPV Vaccine Impact Monitoring Project (HPV-IMPACT), United States, 2008–2016Gargano J, Lewis R, Hunt H, McClung N, Bennett N, Griffin M, Niccolai L, Park I, Powell M, Brackney M, Scahill M, Pemmaraju M, Fink D, Ehlers S, Cleveland A, Unger E, Markowitz L. 962. Trends in Cervical Pre-cancers by Race and Ethnicity During the Human Papillomavirus Vaccine Era, HPV Vaccine Impact Monitoring Project (HPV-IMPACT), United States, 2008–2016 Open Forum Infectious Diseases 2019, 6: s29-s29. PMCID: PMC6809029, DOI: 10.1093/ofid/ofz359.064.
- P836 Trends in anogenital warts since introduction of human papillomavirus vaccines in connecticut, USANiccolai L, Brackney M. P836 Trends in anogenital warts since introduction of human papillomavirus vaccines in connecticut, USA Sexually Transmitted Infections 2019, 95: a351. DOI: 10.1136/sextrans-2019-sti.881.
- O17.5 Declining trends in anogenital warts since HPV vaccine introduction in a large urban health system, 2013–2017Yakely A, Oliviera C, Niccolai L. O17.5 Declining trends in anogenital warts since HPV vaccine introduction in a large urban health system, 2013–2017 Sexually Transmitted Infections 2019, 95: a79. DOI: 10.1136/sextrans-2019-sti.203.
- 66. Compliance with Cervical Cancer Screening Guidelines in Young Females: Rates and Trends of Cervical Cancer Screening in New Haven CountyHosier H, Oliveira C, Pate B, Niccolai L, Sheth S, Vash-Margita A. 66. Compliance with Cervical Cancer Screening Guidelines in Young Females: Rates and Trends of Cervical Cancer Screening in New Haven County Journal Of Pediatric And Adolescent Gynecology 2019, 32: 221. DOI: 10.1016/j.jpag.2019.02.068.
- 2465. A Pilot Program to Improve Human Papillomavirus Vaccination Status of Adolescents at a School-Based Health CenterHansen C, North A, Moriarty-Daley A, Niccolai L. 2465. A Pilot Program to Improve Human Papillomavirus Vaccination Status of Adolescents at a School-Based Health Center Open Forum Infectious Diseases 2018, 5: s739-s739. PMCID: PMC6254943, DOI: 10.1093/ofid/ofy210.2118.
- Shale Gas Activity and Increased Rates of Sexually Transmitted Infections in Ohio, 2000-2016Deziel N, Humeau Z, Elliott E, Warren J, Niccolai L. Shale Gas Activity and Increased Rates of Sexually Transmitted Infections in Ohio, 2000-2016 ISEE Conference Abstracts 2018, 2018 DOI: 10.1289/isesisee.2018.p03.2210.
- Early stages of HIV treatment cascade in people living with HIV in Saint-Petersburg, RussiaVetrova M, Aleksandrova O, Paschenko A, Toropov S, Rassokhin V, Abyshev R, Levina O, Niccolai L, Heimer R. Early stages of HIV treatment cascade in people living with HIV in Saint-Petersburg, Russia AIDS Care 2018, 30: 857-862. PMID: 29325435, DOI: 10.1080/09540121.2017.1417536.
- Cervical Adenocarcinoma in Situ in the United States: Results from Population-based Laboratory Surveillance, 2008–2014Cleveland A, Johnson M, Gargano J, Park I, Griffin M, Niccolai L, Schafer S, Bennett N, Markowitz L, Unger E. Cervical Adenocarcinoma in Situ in the United States: Results from Population-based Laboratory Surveillance, 2008–2014 Open Forum Infectious Diseases 2017, 4: s68-s69. PMCID: PMC5632134, DOI: 10.1093/ofid/ofx162.164.
- P.3.028 Treatment outcomes of newly initiated antiretroviral therapy in HIV-infected people in Saint-Petersburg, RussiaVetrova M, Heimer R, Niccolai L, Aleksandrova O, Paschenko A, Toropov S. P.3.028 Treatment outcomes of newly initiated antiretroviral therapy in HIV-infected people in Saint-Petersburg, Russia European Neuropsychopharmacology 2016, 26: s71-s72. DOI: 10.1016/s0924-977x(16)70078-2.
- Psychiatric Distress, Drug Use, and HIV Viral Load Suppression in RussiaUstinov A, Suvorova A, Belyakov A, Makhamatova A, Levina O, Krupitsky E, Lioznov D, Niccolai L, Heimer R. Psychiatric Distress, Drug Use, and HIV Viral Load Suppression in Russia AIDS And Behavior 2016, 20: 1603-1608. PMID: 26809193, PMCID: PMC4945434, DOI: 10.1007/s10461-016-1297-x.
- THE CRITICAL ASPECTS OF THE EARLY STAGES OF ANTIRETROVIRAL THERAPY PROVISION TO HIV PATIENTSVetrova M, Aleksandrova O, Paschenko A, Toropov S, Abyshev P, Levina O, Belyakov A, Rassokhin V, Niccolai L, Heimer R. THE CRITICAL ASPECTS OF THE EARLY STAGES OF ANTIRETROVIRAL THERAPY PROVISION TO HIV PATIENTS HIV Infection And Immunosuppressive Disorders 2016, 8: 27-37. DOI: 10.22328/2077-9828-2016-8-4-27-37.
- Community Health Worker Perspectives on Barriers to HIV+ Patients' Initiation of and Retention in Antiretroviral Therapy in Rural South AfricaLoeliger K, Niccolai L, Mntungwa N, Moll A, Friedland G, Shenoi S. Community Health Worker Perspectives on Barriers to HIV+ Patients' Initiation of and Retention in Antiretroviral Therapy in Rural South Africa Open Forum Infectious Diseases 2015, 2: 405. DOI: 10.1093/ofid/ofv133.281.
- PHS112 Human Papillomavirus (HPV) Vaccination during well-Child visits in privately insured Males 9-21 years of age in the United States in 2012Zhang D, Huang M, Kulkarni A, Niccolai L. PHS112 Human Papillomavirus (HPV) Vaccination during well-Child visits in privately insured Males 9-21 years of age in the United States in 2012 Value In Health 2015, 18: a266-a267. DOI: 10.1016/j.jval.2015.03.1551.
- 1051Well-child Visits and HPV Vaccination Rates in Privately Insured Females Aged 9-21 Years in the United States, 2007-2012Zhang D, Borse N, Kulkarni A, Niccolai L. 1051Well-child Visits and HPV Vaccination Rates in Privately Insured Females Aged 9-21 Years in the United States, 2007-2012 Open Forum Infectious Diseases 2014, 1: s308-s308. PMCID: PMC5782223, DOI: 10.1093/ofid/ofu052.759.
- 1073Missed Opportunities to Adhere to the ACIP Vaccine Initiation Schedule among Privately Insured Preteens in the United States, 2010-2012Borse N, Kulkarni A, Sen S, Niccolai L. 1073Missed Opportunities to Adhere to the ACIP Vaccine Initiation Schedule among Privately Insured Preteens in the United States, 2010-2012 Open Forum Infectious Diseases 2014, 1: s314-s315. DOI: 10.1093/ofid/ofu052.781.
- P3.133 Potential HIV Transmissions from Infected Drug Injectors and Men Who Have Sex with Men in Saint Petersburg, RussiaWhite E, Niccolai L, Toussova O, Verevochkin S, Kozlov A, Heimer R. P3.133 Potential HIV Transmissions from Infected Drug Injectors and Men Who Have Sex with Men in Saint Petersburg, Russia Sexually Transmitted Infections 2013, 89: a189. DOI: 10.1136/sextrans-2013-051184.0592.
- P3.225 HSV-2 Seroprevalence Among Current Injection Drug Users in EstoniaUusküla A, Raag M, Abel-Ollo K, Talu A, Rüütel K, Salekesin M, Niccolai L, White T, Heimer R. P3.225 HSV-2 Seroprevalence Among Current Injection Drug Users in Estonia Sexually Transmitted Infections 2013, 89: a218. DOI: 10.1136/sextrans-2013-051184.0682.
- Public awareness of the HPV vaccine: A national population-based study.Shrader A, Niccolai L, Mayne S, DiMaio D, Chagpar A. Public awareness of the HPV vaccine: A national population-based study. Journal Of Clinical Oncology 2013, 31: 1574-1574. DOI: 10.1200/jco.2013.31.15_suppl.1574.
- Knowledge of human papillomavirus and anal cancer among men who have sex with men attending a New York City sexually transmitted diseases clinicSanchez D, Pathela P, Niccolai L, Schillinger J. Knowledge of human papillomavirus and anal cancer among men who have sex with men attending a New York City sexually transmitted diseases clinic International Journal Of STD & AIDS 2012, 23: 41-43. PMID: 22362686, DOI: 10.1258/ijsa.2011.011163.
- O1-S02.06 Detection of cervical cancer precursors and associated HPV types in the USA: HPV-IMPACT preliminary resultsPowell S, Hariri S, Steinau M, Bauer H, Bennett N, Bloch K, Schafer S, Niccolai L, Unger E, Markowitz L. O1-S02.06 Detection of cervical cancer precursors and associated HPV types in the USA: HPV-IMPACT preliminary results Sexually Transmitted Infections 2011, 87: a25. DOI: 10.1136/sextrans-2011-050109.12.
- P1-S2.05 Clients of street-based female sex workers and potential bridging of HIV/STI in RussiaNiccolai L, Odinokova V, Safiullina L, Bodanovskaya Z, Heimer R, Levina O, Rusakova M. P1-S2.05 Clients of street-based female sex workers and potential bridging of HIV/STI in Russia Sexually Transmitted Infections 2011, 87: a124. DOI: 10.1136/sextrans-2011-050108.62.
- P2-S1.14 The accuracy of perceptions about sexual concurrency among pregnant adolescents and their partners and the influence of self-reported concurrencySwartzendruber A, Niccolai L, Zenilman J, Jennings J, Sipsma H, Arnold A, Kershaw T. P2-S1.14 The accuracy of perceptions about sexual concurrency among pregnant adolescents and their partners and the influence of self-reported concurrency Sexually Transmitted Infections 2011, 87: a224. DOI: 10.1136/sextrans-2011-050108.292.
- Sexual risk behaviour of the first cohort undergoing screening for enrolment into Phase I/II HIV vaccine trials in South AfricaAndersson K, Van Niekerk R, Niccolai L, Mlungwana O, Holdsworth I, Bogoshi M, McIntyre J, Gray G, Vardas E. Sexual risk behaviour of the first cohort undergoing screening for enrolment into Phase I/II HIV vaccine trials in South Africa International Journal Of STD & AIDS 2009, 20: 95-101. PMID: 19182054, PMCID: PMC3556817, DOI: 10.1258/ijsa.2008.008207.
- Unprotected intercourse for extra money among commercial sex workers in Kinshasa, Democratic Republic of CongoNtumbanzondo M, Dubrow R, Niccolai L, Mwandagalirwa K, Merson M. Unprotected intercourse for extra money among commercial sex workers in Kinshasa, Democratic Republic of Congo AIDS Care 2006, 18: 777-785. PMID: 16971288, DOI: 10.1080/09540120500412824.
- Reproductive Health of Urban Adolescents: Differences in the Behaviors, Cognitions, and Social Context of African-American and Puerto Rican FemalesMilan S, Ethier K, Lewis J, Kershaw T, Niccolai L, Ickovics J. Reproductive Health of Urban Adolescents: Differences in the Behaviors, Cognitions, and Social Context of African-American and Puerto Rican Females Journal Of Youth And Adolescence 2006, 35: 959-967. DOI: 10.1007/s10964-006-9084-z.
- The influence of pregnancy, sexually transmitted diseases, and human immunodeficiency virus perceived susceptibility patterns on sexual risk reduction for adolescent femalesKershaw T, Ethier K, Milan S, Lewis J, Niccolai L, Meade C, Ickovics J. The influence of pregnancy, sexually transmitted diseases, and human immunodeficiency virus perceived susceptibility patterns on sexual risk reduction for adolescent females Journal Of Community Psychology 2005, 33: 313-331. DOI: 10.1002/jcop.20056.
- Perceived susceptibility to pregnancy and sexually transmitted disease among pregnant and nonpregnant adolescentsKershaw T, Niccolai L, Ethier K, Lewis J, Ickovics J. Perceived susceptibility to pregnancy and sexually transmitted disease among pregnant and nonpregnant adolescents Journal Of Community Psychology 2003, 31: 419-434. DOI: 10.1002/jcop.10059.
- Incidence and Predictors of Reinfection with Trichomonas vaginalis in HIV-infected WomenNiccolai L, Kopicko J, Kassie A, Petros H, Clark R, Kissinger P. Incidence and Predictors of Reinfection with Trichomonas vaginalis in HIV-infected Women Sexually Transmitted Diseases 2000, 27: 284-288. PMID: 10821602, DOI: 10.1097/00007435-200005000-00009.
- Ethnic Differences in Body Image Attitudes and Perceptions Among Women Infected with Human Immunodeficiency VirusCLARK R, NICCOLAI L, KISSINGER P, PETERSON Y, BOUVIER V. Ethnic Differences in Body Image Attitudes and Perceptions Among Women Infected with Human Immunodeficiency Virus Journal Of The Academy Of Nutrition And Dietetics 1999, 99: 735-737. PMID: 10361540, DOI: 10.1016/s0002-8223(99)00398-3.
- Disclosure of HIV Status to Sexual Partners: Predictors and Temporal PatternsNICCOLAI L, DORST D, MYERS L, KISSINGER P. Disclosure of HIV Status to Sexual Partners: Predictors and Temporal Patterns Sexually Transmitted Diseases 1999, 26: 281-285. PMID: 10333282, DOI: 10.1097/00007435-199905000-00008.
- Attitudes and Practices of Pharmacy Managers Regarding Needle Sales to Injection Drug UsersFarley T, Niccolai L, Billeter M, Kissinger P, Grace M. Attitudes and Practices of Pharmacy Managers Regarding Needle Sales to Injection Drug Users Journal Of The American Pharmacists Association 1999, 39: 23-26. PMID: 9990183, DOI: 10.1016/s1086-5802(16)30411-9.