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F. Perry Wilson, MD, MSCE

Associate Professor Term; Director, Clinical and Translational Research Accelerator (CTRA); Course Director, Interpretation of the Medical Literature; Co Director, Human Genetics and Clinical Research Core

Research & Publications
Biography
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Research Summary

Dr. Wilson's research focuses on real-time analytics and interventions to prevent and treat acute kidney injury and chronic kidney disease. He has a particular interest in the development and application of personalized medicine techniques to target the proper therapy to the proper patient. He pursues interventional studies to try to help patients live longer, happier lives.

Specialized Terms: Randomized Trials; Acute Kidney Injury; Disparities; Outcomes; CKD progression; Machine-Learning; Personalized Medicine; Uplift modeling.

Extensive Research Description

Dr. Wilson uses epidemiologic and translational research methods to characterize predictors of outcomes in patients with both chronic kidney disease and acute kidney injury. In addition, he uses advanced machine-learning techniques to identify which patients are most likely to respond to a given intervention. These models can reduce the number of individuals exposed to a drug or intervention unnecessarily, reducing adverse events, and lowering costs.

Coauthors

Research Interests

Internal Medicine; Nephrology; Clinical Trial; Decision Support Systems, Clinical; Acute Kidney Injury; Machine Learning; Alert Fatigue, Health Personnel; Implementation Science

Public Health Interests

Epidemiology Methods; Pharmacoepidemiology

Selected Publications

Electronic Alerts to Improve Heart Failure Therapy in Outpatient Practice A Cluster Randomized TrialGhazi L, Yamamoto Y, Riello RJ, Coronel-Moreno C, Martin M, O'Connor KD, Simonov M, Huang J, Olufade T, McDermott J, Dhar R, Inzucchi SE, Velazquez EJ, Wilson FP, Desai NR, Ahmad T. Electronic Alerts to Improve Heart Failure Therapy in Outpatient Practice A Cluster Randomized Trial Journal Of The American College Of Cardiology 2022, 79: 2203-2213. PMID: 35385798, DOI: 10.1016/j.jacc.2022.03.338.
Assessment of Acute Kidney Injury and Longitudinal Kidney Function After Hospital Discharge Among Patients With and Without COVID-19Nugent J, Aklilu A, Yamamoto Y, Simonov M, Li F, Biswas A, Ghazi L, Greenberg J, Mansour S, Moledina D, Wilson FP. Assessment of Acute Kidney Injury and Longitudinal Kidney Function After Hospital Discharge Among Patients With and Without COVID-19 JAMA Network Open 2021, 4: e211095. PMID: 33688965, PMCID: PMC7948062, DOI: 10.1001/jamanetworkopen.2021.1095.
Electronic health record alerts for acute kidney injury: multicenter, randomized clinical trialWilson FP, Martin M, Yamamoto Y, Partridge C, Moreira E, Arora T, Biswas A, Feldman H, Garg AX, Greenberg JH, Hinchcliff M, Latham S, Li F, Lin H, Mansour SG, Moledina DG, Palevsky PM, Parikh CR, Simonov M, Testani J, Ugwuowo U. Electronic health record alerts for acute kidney injury: multicenter, randomized clinical trial The BMJ 2021, 372: m4786. PMID: 33461986, PMCID: PMC8034420, DOI: 10.1136/bmj.m4786.
The Association of COVID-19 With Acute Kidney Injury Independent of Severity of Illness: A Multicenter Cohort StudyMoledina DG, Simonov M, Yamamoto Y, Alausa J, Arora T, Biswas A, Cantley LG, Ghazi L, Greenberg JH, Hinchcliff M, Huang C, Mansour SG, Martin M, Peixoto A, Schulz W, Subair L, Testani JM, Ugwuowo U, Young P, Wilson FP. The Association of COVID-19 With Acute Kidney Injury Independent of Severity of Illness: A Multicenter Cohort Study American Journal Of Kidney Diseases 2021, 77: 490-499.e1. PMID: 33422598, PMCID: PMC7791318, DOI: 10.1053/j.ajkd.2020.12.007.
Real-Time Prediction of Acute Kidney Injury in Hospitalized Adults: Implementation and Proof of ConceptUgwuowo U, Yamamoto Y, Arora T, Saran I, Partridge C, Biswas A, Martin M, Moledina DG, Greenberg JH, Simonov M, Mansour SG, Vela R, Testani JM, Rao V, Rentfro K, Obeid W, Parikh CR, Wilson FP. Real-Time Prediction of Acute Kidney Injury in Hospitalized Adults: Implementation and Proof of Concept American Journal Of Kidney Diseases 2020, 76: 806-814.e1. PMID: 32505812, PMCID: PMC8667815, DOI: 10.1053/j.ajkd.2020.05.003.
How Medicine Works and When it Doesn'tWilson, F. Perry. How Medicine Works and When it Doesn't. Grand Central Publishing, New York, NY, 304 pages, ISBN-13: 9781538723609, 2023.
A randomized clinical trial assessing the effect of automated medication-targeted alerts on acute kidney injury outcomes.Wilson FP, Yamamoto Y, Martin M, Coronel-Moreno C, Li F, Cheng C, Aklilu A, Ghazi L, Greenberg JH, Latham S, Melchinger H, Mansour SG, Moledina DG, Parikh CR, Partridge C, Testani JM, Ugwuowo U. A randomized clinical trial assessing the effect of automated medication-targeted alerts on acute kidney injury outcomes. Nat Commun 2023, 14: 2826. PMID: 37198160, DOI: 10.1038/s41467-023-38532-3.
In-Hospital Observation on Oral Diuretics After Treatment for Acute Decompensated Heart Failure: Evaluating the Utility.Ivey-Miranda J, Rao V, Cox Z, Moreno-Villagomez J, Mahoney D, Maulion C, Bellumkonda L, Turner J, Collins S, Wilson F, Krumholz H, Testani J. In-Hospital Observation on Oral Diuretics After Treatment for Acute Decompensated Heart Failure: Evaluating the Utility. Circulation Heart Failure 2023, e010206. PMID: 36896716, DOI: 10.1161/circheartfailure.122.010206.
Hyperspectral imaging in systemic sclerosis-associated Raynaud phenomenonTeaw S, Gupta A, Williams A, Wilson F, Sumpio B, Sumpio B, Hinchcliff M. Hyperspectral imaging in systemic sclerosis-associated Raynaud phenomenon Arthritis Research & Therapy 2023, 25: 10. PMID: 36670487, PMCID: PMC9854186, DOI: 10.1186/s13075-023-02990-3.
Pragmatic trial of messaging to providers about treatment of acute heart failure: The PROMPT-AHF trialGhazi L, O'Connor K, Yamamoto Y, Fuery M, Sen S, Samsky M, Riello R, Huang J, Olufade T, McDermott J, Inzucchi S, Velazquez E, Wilson F, Desai N, Ahmad T. Pragmatic trial of messaging to providers about treatment of acute heart failure: The PROMPT-AHF trial American Heart Journal 2022, 257: 111-119. PMID: 36493842, DOI: 10.1016/j.ahj.2022.12.002.
Safety and Adequacy of Kidney Biopsy Procedure in Patients with ObesityQian L, Menez S, Hu D, Weinstein J, Melchinger H, Thiessen Philbrook H, Luciano R, Turner J, Perazella M, Corona Villalobos C, Shaw M, Wilson F, Parikh C, Moledina D. Safety and Adequacy of Kidney Biopsy Procedure in Patients with Obesity Kidney360 2022, 10.34067/kid.0006602022. DOI: 10.34067/kid.0006602022.
Safety and Adequacy of Kidney Biopsy Procedure in Patients with ObesityQian L, Menez S, Hu D, Weinstein J, Melchinger H, Thiessen-Philbrook H, Luciano R, Turner J, Perazella M, Villalobos C, Shaw M, Wilson F, Parikh C, Moledina D. Safety and Adequacy of Kidney Biopsy Procedure in Patients with Obesity Kidney360 2022, 4: 98-101. PMID: 36700910, DOI: 10.34067/kid.0006602022.
Effect of intravenous antihypertensives on outcomes of severe hypertension in hospitalized patients without acute target organ damageGhazi L, Li F, Simonov M, Yamamoto Y, Nugent J, Greenberg J, Bakhoum C, Peixoto A, Wilson F. Effect of intravenous antihypertensives on outcomes of severe hypertension in hospitalized patients without acute target organ damage Journal Of Hypertension 2022, 41: 288-294. PMID: 36583354, PMCID: PMC9799038, DOI: 10.1097/hjh.0000000000003328.
Abstract 13604: Sodium-Glucose-Cotransporter-2 Inhibitor (SGLT2i) Exposure in the Immediate Post-Acute Kidney Injury Period in Patients Hospitalized With Acute Heart Failure is Associated With Improved OutcomesKumar S, Aklilu A, Ahmad T, Wilson F. Abstract 13604: Sodium-Glucose-Cotransporter-2 Inhibitor (SGLT2i) Exposure in the Immediate Post-Acute Kidney Injury Period in Patients Hospitalized With Acute Heart Failure is Associated With Improved Outcomes Circulation 2022, 146: a13604-a13604. DOI: 10.1161/circ.146.suppl_1.13604.
Nocturnal Dipping and Kidney Function Decline: Findings From the CKD in Children StudyBakhoum C, Phadke M, Deng Y, Samuels J, Garimella P, Furth S, Wilson F, Ix J. Nocturnal Dipping and Kidney Function Decline: Findings From the CKD in Children Study Kidney International Reports 2022, 7: 2446-2453. DOI: 10.1016/j.ekir.2022.08.002.
Wearables in Cardiovascular DiseaseKumar S, Victoria-Castro AM, Melchinger H, O’Connor K, Psotka M, Desai NR, Ahmad T, Wilson FP. Wearables in Cardiovascular Disease Journal Of Cardiovascular Translational Research 2022, 1-12. PMID: 36085432, DOI: 10.1007/s12265-022-10314-0.
Alerting Clinicians to 1-Year Mortality Risk in Patients Hospitalized With Heart FailureAhmad T, Desai NR, Yamamoto Y, Biswas A, Ghazi L, Martin M, Simonov M, Dhar R, Hsiao A, Kashyap N, Allen L, Velazquez EJ, Wilson FP. Alerting Clinicians to 1-Year Mortality Risk in Patients Hospitalized With Heart Failure JAMA Cardiology 2022, 7: 905-912. PMID: 35947362, PMCID: PMC9366654, DOI: 10.1001/jamacardio.2022.2496.
Urine Uromodulin as a Biomarker of Kidney Tubulointerstitial FibrosisMelchinger H, Calderon-Gutierrez F, Obeid W, Xu L, Shaw MM, Luciano RL, Kuperman M, Moeckel GW, Kashgarian M, Wilson FP, Parikh CR, Moledina DG. Urine Uromodulin as a Biomarker of Kidney Tubulointerstitial Fibrosis Clinical Journal Of The American Society Of Nephrology 2022, 17: 1284-1292. PMID: 35948365, PMCID: PMC9625093, DOI: 10.2215/cjn.04360422.
Nocturnal Dipping and Kidney Function Decline: Findings From the CKD in Children StudyBakhoum C, Phadke M, Deng Y, Samuels J, Garimella P, Furth S, Wilson F, Ix J. Nocturnal Dipping and Kidney Function Decline: Findings From the CKD in Children Study Kidney International Reports 2022, 7: 2446-2453. PMID: 36531891, PMCID: PMC9751682, DOI: 10.1016/j.ekir.2022.08.002.
A Clinical Framework for Evaluating Machine Learning Studies ∗Ghazi L, Ahmad T, Wilson FP. A Clinical Framework for Evaluating Machine Learning Studies ∗ JACC Heart Failure 2022, 10: 648-650. PMID: 35963817, DOI: 10.1016/j.jchf.2022.07.002.
Optimizing the Design and Analysis of Future AKI TrialsLegrand M, Bagshaw SM, Koyner JL, Schulman IH, Mathis MR, Bernholz J, Coca S, Gallagher M, Gaudry S, Liu KD, Mehta RL, Pirracchio R, Ryan A, Steubl D, Stockbridge N, Erlandsson F, Turan A, Wilson FP, Zarbock A, Bokoch MP, Casey JD, Rossignol P, Harhay MO. Optimizing the Design and Analysis of Future AKI Trials Journal Of The American Society Of Nephrology 2022, 33: 1459-1470. PMID: 35831022, PMCID: PMC9342638, DOI: 10.1681/asn.2021121605.
Rationale and design of a pragmatic trial aimed at improving treatment of hyperlipidemia in outpatients with very high risk atherosclerotic cardiovascular disease: A pragmatic trial of messaging to providers about treatment of hyperlipidemia (PROMPT-LIPID)Shah NN, Ghazi L, Yamamoto Y, Martin M, Simonov M, Riello RJ, Faridi KF, Ahmad T, Wilson FP, Desai NR. Rationale and design of a pragmatic trial aimed at improving treatment of hyperlipidemia in outpatients with very high risk atherosclerotic cardiovascular disease: A pragmatic trial of messaging to providers about treatment of hyperlipidemia (PROMPT-LIPID) American Heart Journal 2022, 253: 76-85. PMID: 35841944, PMCID: PMC9936562, DOI: 10.1016/j.ahj.2022.07.002.
Association of vancomycin plus piperacillin–tazobactam with early changes in creatinine versus cystatin C in critically ill adults: a prospective cohort studyMiano TA, Hennessy S, Yang W, Dunn TG, Weisman AR, Oniyide O, Agyekum RS, Turner AP, Ittner CAG, Anderson BJ, Wilson FP, Townsend R, Reilly JP, Giannini HM, Cosgriff CV, Jones TK, Meyer NJ, Shashaty MGS. Association of vancomycin plus piperacillin–tazobactam with early changes in creatinine versus cystatin C in critically ill adults: a prospective cohort study Intensive Care Medicine 2022, 48: 1144-1155. PMID: 35833959, PMCID: PMC9463324, DOI: 10.1007/s00134-022-06811-0.
Pragmatic randomized trial assessing the impact of digital health technology on quality of life in patients with heart failure: Design, rationale and implementationVictoria‐Castro A, Martin M, Yamamoto Y, Ahmad T, Arora T, Calderon F, Desai N, Gerber B, Lee KA, Jacoby D, Melchinger H, Nguyen A, Shaw M, Simonov M, Williams A, Weinstein J, Wilson FP. Pragmatic randomized trial assessing the impact of digital health technology on quality of life in patients with heart failure: Design, rationale and implementation Clinical Cardiology 2022, 45: 839-849. PMID: 35822275, PMCID: PMC9346973, DOI: 10.1002/clc.23848.
Hemoconcentration of Creatinine Minimally Contributes to Changes in Creatinine during the Treatment of Decompensated Heart FailureMaulion C, Chen S, Rao VS, Ivey-Miranda JB, Cox ZL, Mahoney D, Coca SG, Negoianu D, Asher JL, Turner JM, Inker LA, Wilson FP, Testani JM. Hemoconcentration of Creatinine Minimally Contributes to Changes in Creatinine during the Treatment of Decompensated Heart Failure Kidney360 2022, 3: 1003-1010. PMID: 35845336, PMCID: PMC9255871, DOI: 10.34067/kid.0007582021.
Blood pressure response to commonly administered antihypertensives for severe inpatient hypertensionGhazi L, Li F, Chen X, Simonov M, Yamamoto Y, Biswas A, Hanna J, Shah T, Peixoto AJ, Wilson FP. Blood pressure response to commonly administered antihypertensives for severe inpatient hypertension PLOS ONE 2022, 17: e0265497. PMID: 35385506, PMCID: PMC8985959, DOI: 10.1371/journal.pone.0265497.
Urine testing to differentiate glomerular from tubulointerstitial diseases on kidney biopsyTran AC, Melchinger H, Weinstein J, Shaw M, Kent C, Perazella MA, Wilson FP, Parikh CR, Moledina DG. Urine testing to differentiate glomerular from tubulointerstitial diseases on kidney biopsy Practical Laboratory Medicine 2022, 30: e00271. PMID: 35465621, PMCID: PMC9018443, DOI: 10.1016/j.plabm.2022.e00271.
Mortality after acute kidney injury and acute interstitial nephritis in patients prescribed immune checkpoint inhibitor therapyBaker ML, Yamamoto Y, Perazella MA, Dizman N, Shirali AC, Hafez N, Weinstein J, Simonov M, Testani JM, Kluger HM, Cantley LG, Parikh CR, Wilson FP, Moledina DG. Mortality after acute kidney injury and acute interstitial nephritis in patients prescribed immune checkpoint inhibitor therapy Journal For ImmunoTherapy Of Cancer 2022, 10: e004421. PMID: 35354588, PMCID: PMC8968986, DOI: 10.1136/jitc-2021-004421.
Inferior Vena Cava Diameter Measurement Provides Distinct and Complementary Information to Right Atrial Pressure in Acute Decompensated Heart FailureGriffin M, Ivey-Miranda J, McCallum W, Sarnak M, Eder M, Bellumkonda L, Maulion C, Wilson FP, Rao VS, Testani J. Inferior Vena Cava Diameter Measurement Provides Distinct and Complementary Information to Right Atrial Pressure in Acute Decompensated Heart Failure Journal Of Cardiac Failure 2022, 28: 1217-1221. PMID: 35301109, DOI: 10.1016/j.cardfail.2022.02.014.
Predictive Models for Acute Kidney Injury Following Cardiac SurgeryOstermann M, Lumlertgul N, Wilson FP. Predictive Models for Acute Kidney Injury Following Cardiac Surgery JAMA 2022, 327: 927-929. PMID: 35258544, DOI: 10.1001/jama.2022.1823.
Clinically adjudicated deceased donor acute kidney injury and graft outcomesMansour SG, Khoury N, Kodali R, Virmani S, Reese PP, Hall IE, Jia Y, Yamamoto Y, Thiessen-Philbrook HR, Obeid W, Doshi MD, Akalin E, Bromberg JS, Harhay MN, Mohan S, Muthukumar T, Singh P, Weng FL, Moledina DG, Greenberg JH, Wilson FP, Parikh CR. Clinically adjudicated deceased donor acute kidney injury and graft outcomes PLOS ONE 2022, 17: e0264329. PMID: 35239694, PMCID: PMC8893682, DOI: 10.1371/journal.pone.0264329.
Angiopoietins as Prognostic Markers for Future Kidney Disease and Heart Failure Events after Acute Kidney InjuryMansour SG, Bhatraju PK, Coca SG, Obeid W, Wilson FP, Stanaway IB, Jia Y, Thiessen-Philbrook H, Go AS, Ikizler TA, Siew ED, Chinchilli VM, Hsu CY, Garg AX, Reeves WB, Liu KD, Kimmel PL, Kaufman JS, Wurfel MM, Himmelfarb J, Parikh SM, Parikh CR. Angiopoietins as Prognostic Markers for Future Kidney Disease and Heart Failure Events after Acute Kidney Injury Journal Of The American Society Of Nephrology 2022, 33: 613-627. PMID: 35017169, PMCID: PMC8975075, DOI: 10.1681/asn.2021060757.
Multiscale PHATE identifies multimodal signatures of COVID-19Kuchroo M, Huang J, Wong P, Grenier JC, Shung D, Tong A, Lucas C, Klein J, Burkhardt DB, Gigante S, Godavarthi A, Rieck B, Israelow B, Simonov M, Mao T, Oh JE, Silva J, Takahashi T, Odio CD, Casanovas-Massana A, Fournier J, Farhadian S, Dela Cruz C, Ko A, Hirn M, Wilson F, Hussin J, Wolf G, Iwasaki A, Krishnaswamy S. Multiscale PHATE identifies multimodal signatures of COVID-19 Nature Biotechnology 2022, 40: 681-691. PMID: 35228707, PMCID: PMC10015653, DOI: 10.1038/s41587-021-01186-x.
Severe inpatient hypertension prevalence and blood pressure response to antihypertensive treatmentGhazi L, Li F, Chen X, Simonov M, Yamamoto Y, Biswas A, Hanna J, Shah T, Townsend R, Peixoto A, Wilson FP. Severe inpatient hypertension prevalence and blood pressure response to antihypertensive treatment Journal Of Clinical Hypertension 2022, 24: 339-349. PMID: 35174627, PMCID: PMC8925013, DOI: 10.1111/jch.14431.
Prevalence of Secondary Hypertension in Otherwise Healthy Youths with a New Diagnosis of Hypertension: A Meta-AnalysisNugent JT, Young C, Funaro MC, Jiang K, Saran I, Ghazi L, Wilson FP, Greenberg JH. Prevalence of Secondary Hypertension in Otherwise Healthy Youths with a New Diagnosis of Hypertension: A Meta-Analysis The Journal Of Pediatrics 2022, 244: 30-37.e10. PMID: 35120981, PMCID: PMC9086113, DOI: 10.1016/j.jpeds.2022.01.047.
Excessive Blood Pressure Response to Clonidine in Hospitalized Patients With Asymptomatic Severe Hypertension.Hanna J, Ghazi L, Yamamoto Y, Simonov M, Shah T, Wilson F, Peixoto A. Excessive Blood Pressure Response to Clonidine in Hospitalized Patients With Asymptomatic Severe Hypertension. American Journal Of Hypertension 2022, 35: 433-440. PMID: 35038322, PMCID: PMC9088839, DOI: 10.1093/ajh/hpac004.
Development and external validation of a diagnostic model for biopsy-proven acute interstitial nephritis using electronic health record data.Moledina DG, Eadon MT, Calderon F, Yamamoto Y, Shaw M, Perazella MA, Simonov M, Luciano R, Schwantes-An TH, Moeckel G, Kashgarian M, Kuperman M, Obeid W, Cantley LG, Parikh CR, Wilson FP. Development and external validation of a diagnostic model for biopsy-proven acute interstitial nephritis using electronic health record data. Nephrology Dialysis Transplantation 2021, 37: 2214-2222. PMID: 34865148, PMCID: PMC9755995, DOI: 10.1093/ndt/gfab346.
Rationale and design of a cluster-randomized pragmatic trial aimed at improving use of guideline directed medical therapy in outpatients with heart failure: PRagmatic trial of messaging to providers about treatment of heart failure (PROMPT-HF)Ghazi L, Desai NR, Simonov M, Yamamoto Y, O'Connor KD, Riello RJ, Huang J, Olufade T, McDermott J, Inzucchi SE, Velazquez EJ, Wilson FP, Ahmad T. Rationale and design of a cluster-randomized pragmatic trial aimed at improving use of guideline directed medical therapy in outpatients with heart failure: PRagmatic trial of messaging to providers about treatment of heart failure (PROMPT-HF) American Heart Journal 2021, 244: 107-115. PMID: 34808104, DOI: 10.1016/j.ahj.2021.11.010.
FGF-23 (Fibroblast Growth Factor-23) and Cardiorenal InteractionsIvey-Miranda JB, Stewart B, Cox ZL, McCallum W, Maulion C, Gleason O, Meegan G, Amatruda JG, Moreno-Villagomez J, Mahoney D, Turner JM, Wilson FP, Estrella MM, Shlipak MG, Rao VS, Testani JM. FGF-23 (Fibroblast Growth Factor-23) and Cardiorenal Interactions Circulation Heart Failure 2021, 14: e008385. PMID: 34689571, PMCID: PMC8782627, DOI: 10.1161/circheartfailure.121.008385.
Prognostic Significance of Urinary Biomarkers in Patients Hospitalized With COVID-19Menez S, Moledina DG, Thiessen-Philbrook H, Wilson FP, Obeid W, Simonov M, Yamamoto Y, Corona-Villalobos CP, Chang C, Garibaldi BT, Clarke W, Farhadian S, Dela Cruz C, Coca SG, Parikh CR, Investigators T, Ko A, Iwasaki A, Farhadian S, Nelson A, Casanovas-Massana A, White E, Schulz W, Coppi A, Young P, Nunez A, Shepard D, Matos I, Strong Y, Anastasio K, Brower K, Kuang M, Chiorazzi M, Bermejo S, Vijayakumar P, Geng B, Fournier J, Minasyan M, Muenker M, Moore A, Nadkarni G. Prognostic Significance of Urinary Biomarkers in Patients Hospitalized With COVID-19 American Journal Of Kidney Diseases 2021, 79: 257-267.e1. PMID: 34710516, PMCID: PMC8542781, DOI: 10.1053/j.ajkd.2021.09.008.
Abstract 57: Risk Factors For Severe Reductions In Blood Pressure After Treatment Of Severe Inpatient HypertensionGhazi L, Li F, Chen E, Simonov M, Yamamoto Y, Biswas A, Hanna J, Shah T, Peixoto A, Wilson F. Abstract 57: Risk Factors For Severe Reductions In Blood Pressure After Treatment Of Severe Inpatient Hypertension Hypertension 2021, 78 DOI: 10.1161/hyp.78.suppl_1.57.
Abstract P110: Intravenous Hydralazine Effect On Blood Pressure Following Severe Inpatient Hypertension DevelopmentGhazi L, Li F, Chen E, SIMONOV M, Yamamoto Y, Biswas A, Hanna J, Shah T, Peixoto A, Wilson F. Abstract P110: Intravenous Hydralazine Effect On Blood Pressure Following Severe Inpatient Hypertension Development Hypertension 2021, 78 DOI: 10.1161/hyp.78.suppl_1.p110.
Renal negative pressure treatment as a novel therapy for heart failure-induced renal dysfunctionRao VS, Maulion C, Asher JL, Ivey-Miranda J, Cox ZL, Moreno-Villagomez J, Mahoney D, Turner JM, Wilson FP, Wilcox CS, Testani J. Renal negative pressure treatment as a novel therapy for heart failure-induced renal dysfunction AJP Regulatory Integrative And Comparative Physiology 2021, 321: r588-r594. PMID: 34405731, DOI: 10.1152/ajpregu.00115.2021.
Changes in Body Composition, Muscle Strength, and Fat Distribution Following Kidney TransplantationDienemann T, Ziolkowski SL, Bender S, Goral S, Long J, Baker JF, Shults J, Zemel BS, Reese PP, Wilson FP, Leonard MB. Changes in Body Composition, Muscle Strength, and Fat Distribution Following Kidney Transplantation American Journal Of Kidney Diseases 2021, 78: 816-825. PMID: 34352286, PMCID: PMC8608755, DOI: 10.1053/j.ajkd.2020.11.032.
Generating hard-to-obtain information from easy-to-obtain information: Applications in drug discovery and clinical inferenceAmodio M, Shung D, Burkhardt DB, Wong P, Simonov M, Yamamoto Y, van Dijk D, Wilson FP, Iwasaki A, Krishnaswamy S. Generating hard-to-obtain information from easy-to-obtain information: Applications in drug discovery and clinical inference Patterns 2021, 2: 100288. PMID: 34286302, PMCID: PMC8276014, DOI: 10.1016/j.patter.2021.100288.
1014-P: The Impact of Baseline A1C and Admission Glucose on Mortality among Patients with Diabetes Hospitalized with COVID-19BRANCALE J, ATHONVARANGKUL D, SIMONOV M, ALAUSA J, SUBAIR L, HAJDUK A, KANG Y, ARORA T, WILSON F, JASTREBOFF A, LIPSKA K. 1014-P: The Impact of Baseline A1C and Admission Glucose on Mortality among Patients with Diabetes Hospitalized with COVID-19 Diabetes 2021, 70 DOI: 10.2337/db21-1014-p.
Introduction to Supervised Machine Learning.Biswas A, Saran I, Wilson FP. Introduction to Supervised Machine Learning. Kidney360 2021, 2: 878-880. PMID: 35373058, PMCID: PMC8791341, DOI: 10.34067/kid.0000182021.
REVeAL-HF Design and Rationale of a Pragmatic Randomized Controlled Trial Embedded Within Routine Clinical PracticeAhmad T, Yamamoto Y, Biswas A, Ghazi L, Martin M, Simonov M, Hsiao A, Kashyap N, Velazquez EJ, Desai NR, Wilson FP. REVeAL-HF Design and Rationale of a Pragmatic Randomized Controlled Trial Embedded Within Routine Clinical Practice JACC Heart Failure 2021, 9: 409-419. PMID: 33992566, DOI: 10.1016/j.jchf.2021.03.006.
Predicting patients with false negative SARS-CoV-2 testing at hospital admission: A retrospective multi-center studyGhazi L, Simonov M, Mansour SG, Moledina DG, Greenberg JH, Yamamoto Y, Biswas A, Wilson FP. Predicting patients with false negative SARS-CoV-2 testing at hospital admission: A retrospective multi-center study PLOS ONE 2021, 16: e0251376. PMID: 33979353, PMCID: PMC8115794, DOI: 10.1371/journal.pone.0251376.
AACC Guidance Document on Laboratory Investigation of Acute Kidney InjuryEl-Khoury JM, Hoenig MP, Jones GRD, Lamb EJ, Parikh CR, Tolan NV, Wilson FP. AACC Guidance Document on Laboratory Investigation of Acute Kidney Injury The Journal Of Applied Laboratory Medicine 2021, 6: jfab020-. PMID: 33973621, DOI: 10.1093/jalm/jfab020.
A Comparison Study of Coronavirus Disease 2019 Outcomes in Hospitalized Kidney Transplant Recipients.Mansour SG, Malhotra D, Simonov M, Yamamoto Y, Arora T, Subair L, Alausa J, Moledina DG, Greenberg JH, Wilson FP, Marin EP. A Comparison Study of Coronavirus Disease 2019 Outcomes in Hospitalized Kidney Transplant Recipients. Kidney360 2021, 2: 494-506. PMID: 35369023, PMCID: PMC8786009, DOI: 10.34067/kid.0005652020.
Rationale and design of the Kidney Precision Medicine Projectde Boer IH, Alpers CE, Azeloglu EU, Balis UGJ, Barasch JM, Barisoni L, Blank KN, Bomback AS, Brown K, Dagher PC, Dighe AL, Eadon MT, El-Achkar TM, Gaut JP, Hacohen N, He Y, Hodgin JB, Jain S, Kellum JA, Kiryluk K, Knight R, Laszik ZG, Lienczewski C, Mariani LH, McClelland RL, Menez S, Moledina DG, Mooney SD, O’Toole J, Palevsky PM, Parikh CR, Poggio ED, Rosas SE, Rosengart MR, Sarwal MM, Schaub JA, Sedor JR, Sharma K, Steck B, Toto RD, Troyanskaya OG, Tuttle KR, Vazquez MA, Waikar SS, Williams K, Wilson FP, Zhang K, Iyengar R, Kretzler M, Himmelfarb J, Project K, Knight R, Lecker S, Stillman I, Waikar S, Mcmahon G, Weins A, Short S, Hacohen N, Hoover P, Aulisio M, Cooperman L, Herlitz L, O’Toole J, Poggio E, Sedor J, Jolly S, Appelbaum P, Balderes O, Barasch J, Bomback A, Canetta P, d’Agati V, Kiryluk K, Kudose S, Mehl K, Radhakrishnan J, Weng C, Barisoni L, Alexandrov T, Ashkar T, Barwinska D, Dagher P, Dunn K, Eadon M, Ferkowicz M, Kelly K, Sutton T, Winfree S, Menez S, Parikh C, Rosenberg A, Villalobos P, Malik R, Fine D, Atta M, Trujillo J, Slack A, Rosas S, Williams M, Azeloglu E, He C, Iyengar R, Hansen J, Parikh S, Rovin B, Anderton C, Pasa-Tolic L, Velickovic D, Lukowski J, Oliver G, Ardayfio J, Bebiak J, Brown K, Campbell T, Campbell C, Hayashi L, Jefferson N, Koewler R, Roberts G, Saul J, Shpigel A, Stutzke E, Wright L, Miegs L, Pinkeney R, Sealfon R, Troyanskaya O, Tuttle K, Dobi D, Goltsev Y, Lake B, Zhang K, Joanes M, Laszik Z, Schroeder A, Sarwal M, Sigdel T, Balis U, Blanc V, He O, Hodgin J, Kretzler M, Mariani L, Menon R, Otto E, Schaub J, Steck B, Lienczewski C, Eddy S, Elder M, Hall D, Kellum J, Kruth M, Murugan R, Palevsky P, Randhawa P, Rosengart M, Sims-Lucas S, Stefanick M, Stull S, Tublin M, Alpers C, de Boer I, Dighe A, Himmelfarb J, Mcclelland R, Mooney S, Shankland S, Williams K, Blank K, Carson J, Dowd F, Drager Z, Park C, Sharma K, Zhang G, Bansal S, Venkatachalam M, Kermani A, Lee S, Lu C, Miller T, Moe O, Park H, Sambandam K, Sanchez F, Torrealba J, Robert T, Vazquez M, Wang N, Gaut J, Jain S, Vijayan A, Luciano R, Moledina D, Ugochukwu U, Wilson F, Alfano S. Rationale and design of the Kidney Precision Medicine Project Kidney International 2021, 99: 498-510. PMID: 33637194, PMCID: PMC8330551, DOI: 10.1016/j.kint.2020.08.039.
A neutrophil activation signature predicts critical illness and mortality in COVID-19Meizlish ML, Pine AB, Bishai JD, Goshua G, Nadelmann ER, Simonov M, Chang CH, Zhang H, Shallow M, Bahel P, Owusu K, Yamamoto Y, Arora T, Atri DS, Patel A, Gbyli R, Kwan J, Won CH, Dela Cruz C, Price C, Koff J, King BA, Rinder HM, Wilson FP, Hwa J, Halene S, Damsky W, van Dijk D, Lee AI, Chun HJ. A neutrophil activation signature predicts critical illness and mortality in COVID-19 Blood Advances 2021, 5: 1164-1177. PMID: 33635335, PMCID: PMC7908851, DOI: 10.1182/bloodadvances.2020003568.
Natriuretic Equation to Predict Loop Diuretic Response in Patients With Heart FailureRao VS, Ivey-Miranda JB, Cox ZL, Riello R, Griffin M, Fleming J, Soucier R, Sangkachand P, O'Brien M, LoRusso F, D'Ambrosi J, Churchwell K, Mahoney D, Bellumkonda L, Asher JL, Maulion C, Turner JM, Wilson FP, Collins SP, Testani JM. Natriuretic Equation to Predict Loop Diuretic Response in Patients With Heart Failure Journal Of The American College Of Cardiology 2021, 77: 695-708. PMID: 33573739, PMCID: PMC8114781, DOI: 10.1016/j.jacc.2020.12.022.
Subtyping CKD Patients by Consensus Clustering: The Chronic Renal Insufficiency Cohort (CRIC) StudyZheng Z, Waikar SS, Schmidt IM, Landis JR, Hsu CY, Shafi T, Feldman HI, Anderson AH, Wilson FP, Chen J, Rincon-Choles H, Ricardo AC, Saab G, Isakova T, Kallem R, Fink JC, Rao PS, Xie D, Yang W, Investigators C. Subtyping CKD Patients by Consensus Clustering: The Chronic Renal Insufficiency Cohort (CRIC) Study Journal Of The American Society Of Nephrology 2021, 32: 639-653. PMID: 33462081, PMCID: PMC7920178, DOI: 10.1681/asn.2020030239.
Computer vision applied to dual-energy computed tomography images for precise calcinosis cutis quantification in patients with systemic sclerosisChandrasekaran AC, Fu Z, Kraniski R, Wilson FP, Teaw S, Cheng M, Wang A, Ren S, Omar IM, Hinchcliff ME. Computer vision applied to dual-energy computed tomography images for precise calcinosis cutis quantification in patients with systemic sclerosis Arthritis Research & Therapy 2021, 23: 6. PMID: 33407814, PMCID: PMC7788847, DOI: 10.1186/s13075-020-02392-9.
Prediction of outcomes after acute kidney injury in hospitalised patients: protocol for a systematic reviewArora T, Martin M, Grimshaw A, Mansour S, Wilson FP. Prediction of outcomes after acute kidney injury in hospitalised patients: protocol for a systematic review BMJ Open 2020, 10: e042035. PMID: 33371041, PMCID: PMC7757434, DOI: 10.1136/bmjopen-2020-042035.
Predicting patients with false negative SARS-CoV-2 testing at hospital admission: A retrospective multi-center study.Ghazi L, Simonov M, Mansour S, Moledina D, Greenberg J, Yamamoto Y, Biswas A, Wilson FP. Predicting patients with false negative SARS-CoV-2 testing at hospital admission: A retrospective multi-center study. MedRxiv : The Preprint Server For Health Sciences 2020 PMID: 33300016, PMCID: PMC7724687, DOI: 10.1101/2020.11.30.20241414.
Urine interleukin-9 and tumor necrosis factor-α for prognosis of human acute interstitial nephritisMoledina DG, Wilson FP, Kukova L, Obeid W, Luciano R, Kuperman M, Moeckel GW, Kashgarian M, Perazella MA, Cantley LG, Parikh CR. Urine interleukin-9 and tumor necrosis factor-α for prognosis of human acute interstitial nephritis Nephrology Dialysis Transplantation 2020, 36: 1851-1858. PMID: 33125471, PMCID: PMC8476079, DOI: 10.1093/ndt/gfaa169.
Variation in Best Practice Measures in Patients With Severe Hospital-Acquired Acute Kidney Injury: A Multicenter StudyMoledina DG, Belliveau O, Yamamoto Y, Arora T, Carey KA, Churpek M, Martin M, Partridge CM, Mansour SG, Parikh CR, Koyner JL, Wilson FP. Variation in Best Practice Measures in Patients With Severe Hospital-Acquired Acute Kidney Injury: A Multicenter Study American Journal Of Kidney Diseases 2020, 77: 547-549. PMID: 33075389, PMCID: PMC8672301, DOI: 10.1053/j.ajkd.2020.08.013.
Acute Kidney Injury in Decompensated Cirrhosis Is Associated With Both Hypo‐coagulable and Hyper‐coagulable FeaturesZanetto A, Rinder HM, Campello E, Saggiorato G, Deng Y, Ciarleglio M, Wilson FP, Senzolo M, Gavasso S, Bulato C, Simioni P, Garcia‐Tsao G. Acute Kidney Injury in Decompensated Cirrhosis Is Associated With Both Hypo‐coagulable and Hyper‐coagulable Features Hepatology 2020, 72: 1327-1340. PMID: 32614088, PMCID: PMC8672302, DOI: 10.1002/hep.31443.
COVID-19 infections and outcomes in a live registry of heart failure patients across an integrated health care systemCaraballo C, McCullough M, Fuery MA, Chouairi F, Keating C, Ravindra NG, Miller PE, Malinis M, Kashyap N, Hsiao A, Wilson FP, Curtis JP, Grant M, Velazquez EJ, Desai NR, Ahmad T. COVID-19 infections and outcomes in a live registry of heart failure patients across an integrated health care system PLOS ONE 2020, 15: e0238829. PMID: 32997657, PMCID: PMC7526909, DOI: 10.1371/journal.pone.0238829.
Characteristics and Outcomes of Individuals With Pre-existing Kidney Disease and COVID-19 Admitted to Intensive Care Units in the United StatesFlythe JE, Assimon MM, Tugman MJ, Chang EH, Gupta S, Shah J, Sosa MA, Renaghan AD, Melamed ML, Wilson FP, Neyra JA, Rashidi A, Boyle SM, Anand S, Christov M, Thomas LF, Edmonston D, Leaf DE, Walther C, Anumudu S, Arunthamakun J, Kopecky K, Milligan G, McCullough P, Nguyen T, Shaefi S, Krajewski M, Shankar S, Pannu A, Valencia J, Waikar S, Kibbelaar Z, Athavale A, Hart P, Upadhyay S, Vohra I, Green A, Rachoin J, Schorr C, Shea L, Edmonston D, Mosher C, Shehata A, Cohen Z, Allusson V, Bambrick-Santoyo G, Bhatti N, Mehta B, Williams A, Brenner S, Walters P, Go R, Rose K, Chan L, Mathews K, Coca S, Altman D, Saha A, Soh H, Wen H, Bose S, Leven E, Wang J, Mosoyan G, Nadkarni G, Pattharanitima P, Gallagher E, Friedman A, Guirguis J, Kapoor R, Meshberger C, Kelly K, Parikh C, Garibaldi B, Corona-Villalobos C, Wen Y, Menez S, Malik R, Cervantes C, Gautam S, Mallappallil M, Ouyang J, John S, Yap E, Melaku Y, Mohamed I, Bajracharya S, Puri I, Thaxton M, Bhattacharya J, Wagner J, Boudourakis L, Nguyen H, Ahoubim A, Kashani K, Tehranian S, Thomas L, Sirganagari D, Guru P, Zhou Y, Bergl P, Rodriguez J, Shah J, Gupta M, Kumar P, Lazarous D, Kassaye S, Melamed M, Johns T, Mocerino R, Prudhvi K, Zhu D, Levy R, Azzi Y, Fisher M, Yunes M, Sedaliu K, Golestaneh L, Brogan M, Kumar N, Chang M, Thakkar J, Raichoudhury R, Athreya A, Farag M, Schenck E, Cho S, Plataki M, Alvarez-Mulett S, Gomez-Escobar L, Pan D, Lee S, Krishnan J, Whalen W, Charytan D, Macina A, Chaudhry S, Wu B, Modersitzki F, Srivastava A, Leidner A, Martinez C, Kruser J, Wunderink R, Hodakowski A, Velez J, Price-Haywood E, Matute-Trochez L, Hasty A, Mohamed M, Avasare R, Zonies D, Leaf D, Gupta S, Sise M, Newman E, Abu Omar S, Pokharel K, Sharma S, Singh H, Correa S, Shaukat T, Kamal O, Wang W, Yang H, Boateng J, Lee M, Strohbehn I, Li J, Mueller A, Redfern R, Cairl N, Naimy G, Abu-Saif A, Hall D, Bickley L, Rowan C, Madhani-Lovely F, Peev V, Reiser J, Byun J, Vissing A, Kapania E, Post Z, Patel N, Hermes J, Sutherland A, Patrawalla A, Finkel D, Danek B, Arikapudi S, Paer J, Cangialosi P, Liotta M, Radbel J, Puri S, Sunderram J, Scharf M, Ahmed A, Berim I, Vatson J, Anand S, Levitt J, Garcia P, Boyle S, Song R, Zhang J, Woo S, Deng X, Katz-Greenberg G, Senter K, Sharshir M, Rusnak V, Ali M, Bansal A, Podoll A, Chonchol M, Sharma S, Burnham E, Rashidi A, Hejal R, Judd E, Latta L, Tolwani A, Albertson T, Adams J, Reagan R, Chang S, Beutler R, Monica S, Schulze C, Macedo E, Rhee H, Liu K, Jotwani V, Koyner J, Kunczt A, Shah C, Jaikaransingh V, Toth-Manikowski S, Joo M, Lash J, Neyra J, Chaaban N, Dy R, Iardino A, Au E, Sharma J, Sosa M, Taldone S, Contreras G, De La Zerda D, Gershengorn H, Hayek S, Blakely P, Berlin H, Azam T, Shadid H, Pan M, Hayer P, Meloche C, Feroze R, Kaakati R, Perry D, Bitar A, Anderson E, Padalia K, Donnelly J, Admon A, Flythe J, Tugman M, Chang E, Brown B, Leonberg-Yoo A, Spiardi R, Miano T, Roche M, Vasquez C, Bansal A, Ernecoff N, Kapoor S, Verma S, Chen H, Kovesdy C, Molnar M, Azhar A, Hedayati S, Nadamuni M, Shastri S, Willett D, Short S, Renaghan A, Enfield K, Bhatraju P, Malik A, Semler M, Vijayan A, Joy C, Li T, Goldberg S, Kao P, Schumaker G, Goyal N, Faugno A, Schumaker G, Hsu C, Tariq A, Meyer L, Kshirsagar R, Weiner D, Jose A, Christov M, Griffiths J, Gupta S, Kapoor A, Wilson P, Arora T, Ugwuowo U. Characteristics and Outcomes of Individuals With Pre-existing Kidney Disease and COVID-19 Admitted to Intensive Care Units in the United States American Journal Of Kidney Diseases 2020, 77: 190-203.e1. PMID: 32961244, PMCID: PMC7501875, DOI: 10.1053/j.ajkd.2020.09.003.
Geographical Affiliation with Top 10 NIH-Funded Academic Medical Centers and Differences Between Mortality from Cardiovascular Disease and CancerAngraal S, Caraballo C, Kahn P, Bhatnagar A, Singh B, Wilson FP, Fiuzat M, O'Connor CM, Allen LA, Desai NR, Mamtani R, Ahmad T. Geographical Affiliation with Top 10 NIH-Funded Academic Medical Centers and Differences Between Mortality from Cardiovascular Disease and Cancer American Heart Journal 2020, 230: 54-58. PMID: 32950462, PMCID: PMC7734611, DOI: 10.1016/j.ahj.2020.08.014.
A neutrophil activation signature predicts critical illness and mortality in COVID-19.Meizlish ML, Pine AB, Bishai JD, Goshua G, Nadelmann ER, Simonov M, Chang CH, Zhang H, Shallow M, Bahel P, Owusu K, Yamamoto Y, Arora T, Atri DS, Patel A, Gbyli R, Kwan J, Won CH, Dela Cruz C, Price C, Koff J, King BA, Rinder HM, Wilson FP, Hwa J, Halene S, Damsky W, van Dijk D, Lee AI, Chun H. A neutrophil activation signature predicts critical illness and mortality in COVID-19. MedRxiv : The Preprint Server For Health Sciences 2020 PMID: 32908988, PMCID: PMC7480036, DOI: 10.1101/2020.09.01.20183897.
Novel Risk Factors for Progression of Diabetic and Nondiabetic CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) StudyAnderson AH, Xie D, Wang X, Baudier RL, Orlandi P, Appel LJ, Dember LM, He J, Kusek JW, Lash JP, Navaneethan SD, Ojo A, Rahman M, Roy J, Scialla JJ, Sondheimer JH, Steigerwalt SP, Wilson FP, Wolf M, Feldman HI, Investigators C, Go A, Townsend R. Novel Risk Factors for Progression of Diabetic and Nondiabetic CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study American Journal Of Kidney Diseases 2020, 77: 56-73.e1. PMID: 32866540, PMCID: PMC7752839, DOI: 10.1053/j.ajkd.2020.07.011.
Cystatin C and Muscle Mass in Patients With Heart FailureIvey-Miranda JB, Inker LA, Griffin M, Rao V, Maulion C, Turner JM, Wilson FP, Tang WHW, Levey AS, Testani JM. Cystatin C and Muscle Mass in Patients With Heart Failure Journal Of Cardiac Failure 2020, 27: 48-56. PMID: 32750487, PMCID: PMC8672303, DOI: 10.1016/j.cardfail.2020.07.013.
THU137 Acute kidney injury is associated with reversible platelet dysfunction in hospitalized patients with decompensated cirrhosisZanetto A, Rinder H, Deng Y, Ciarleglio M, Wilson F, Bulato C, Simioni P, Garcia-Tsao G. THU137 Acute kidney injury is associated with reversible platelet dysfunction in hospitalized patients with decompensated cirrhosis Journal Of Hepatology 2020, 73: s206-s207. DOI: 10.1016/s0168-8278(20)30921-1.
Results from the TRIBE-AKI Study found associations between post-operative blood biomarkers and risk of chronic kidney disease after cardiac surgeryMenez S, Moledina DG, Garg AX, Thiessen-Philbrook H, McArthur E, Jia Y, Liu C, Obeid W, Mansour SG, Koyner JL, Shlipak MG, Wilson FP, Coca SG, Parikh CR. Results from the TRIBE-AKI Study found associations between post-operative blood biomarkers and risk of chronic kidney disease after cardiac surgery Kidney International 2020, 99: 716-724. PMID: 32721447, PMCID: PMC8077034, DOI: 10.1016/j.kint.2020.06.037.
Development and Validation of the Quick COVID-19 Severity Index: A Prognostic Tool for Early Clinical DecompensationHaimovich AD, Ravindra NG, Stoytchev S, Young HP, Wilson FP, van Dijk D, Schulz WL, Taylor RA. Development and Validation of the Quick COVID-19 Severity Index: A Prognostic Tool for Early Clinical Decompensation Annals Of Emergency Medicine 2020, 76: 442-453. PMID: 33012378, PMCID: PMC7373004, DOI: 10.1016/j.annemergmed.2020.07.022.
Patient factors associated with SARS‐CoV‐2 in an admitted emergency department populationHaimovich A, Warner F, Young HP, Ravindra NG, Sehanobish A, Gong G, Wilson FP, Dijk D, Schulz W, Taylor R. Patient factors associated with SARS‐CoV‐2 in an admitted emergency department population Journal Of The American College Of Emergency Physicians Open 2020, 1: 569-577. PMID: 32838371, PMCID: PMC7280703, DOI: 10.1002/emp2.12145.
Empagliflozin in Heart FailureGriffin M, Rao VS, Ivey-Miranda J, Fleming J, Mahoney D, Maulion C, Suda N, Siwakoti K, Ahmad T, Jacoby D, Riello R, Bellumkonda L, Cox Z, Collins S, Jeon S, Turner JM, Wilson FP, Butler J, Inzucchi SE, Testani JM. Empagliflozin in Heart Failure Circulation 2020, 142: 1028-1039. PMID: 32410463, PMCID: PMC7521417, DOI: 10.1161/circulationaha.120.045691.
A Time-Updated, Parsimonious Model to Predict AKI in Hospitalized ChildrenSandokji I, Yamamoto Y, Biswas A, Arora T, Ugwuowo U, Simonov M, Saran I, Martin M, Testani JM, Mansour S, Moledina DG, Greenberg JH, Wilson FP. A Time-Updated, Parsimonious Model to Predict AKI in Hospitalized Children Journal Of The American Society Of Nephrology 2020, 31: 1348-1357. PMID: 32381598, PMCID: PMC7269342, DOI: 10.1681/asn.2019070745.
1002 ACUTE KIDNEY INJURY IS ASSOCIATED WITH REVERSIBLE PLATELET DYSFUNCTION IN HOSPITALIZED PATIENTS WITH DECOMPENSATED CIRRHOSIS.Zanetto A, Rinder H, Deng Y, Ciarleglio M, Wilson F, Bulato C, Simioni P, Garcia-Tsao G. 1002 ACUTE KIDNEY INJURY IS ASSOCIATED WITH REVERSIBLE PLATELET DYSFUNCTION IN HOSPITALIZED PATIENTS WITH DECOMPENSATED CIRRHOSIS. Gastroenterology 2020, 158: s-1301. DOI: 10.1016/s0016-5085(20)33914-7.
Use of Proton Pump Inhibitors Increases Risk of Incident Kidney StonesSimonov M, Abel EA, Skanderson M, Masoud A, Hauser RG, Brandt CA, Wilson FP, Laine L. Use of Proton Pump Inhibitors Increases Risk of Incident Kidney Stones Clinical Gastroenterology And Hepatology 2020, 19: 72-79.e21. PMID: 32147588, PMCID: PMC7483196, DOI: 10.1016/j.cgh.2020.02.053.
EFFECT OF LOOP DIURETICS ON THE FRACTIONAL EXCRETION OF UREA IN DECOMPENSATED HEART FAILURECox Z, Sury K, Rao V, Ivey-Miranda J, Griffin M, Mahoney D, Gomez N, Inker L, Coca S, Turner J, Wilson F, Testani J. EFFECT OF LOOP DIURETICS ON THE FRACTIONAL EXCRETION OF UREA IN DECOMPENSATED HEART FAILURE Journal Of The American College Of Cardiology 2020, 75: 758. DOI: 10.1016/s0735-1097(20)31385-1.
Real World Use of Hypertonic Saline in Refractory Acute Decompensated Heart Failure A U.S. Center’s ExperienceGriffin M, Soufer A, Goljo E, Colna M, Rao VS, Jeon S, Raghavendra P, D'Ambrosi J, Riello R, Coca SG, Mahoney D, Jacoby D, Ahmad T, Chen M, Tang WHW, Turner J, Mullens W, Wilson FP, Testani JM. Real World Use of Hypertonic Saline in Refractory Acute Decompensated Heart Failure A U.S. Center’s Experience JACC Heart Failure 2020, 8: 199-208. PMID: 32035891, PMCID: PMC7814403, DOI: 10.1016/j.jchf.2019.10.012.
Acute kidney injury is associated with reversible platelet dysfunction in hospitalized patients with decompensated cirrhosisZanetto A, Rinder H, Deng Y, Ciarleglio M, Wilson F, Bulato C, Simioni P, Garcia-Tsao G. Acute kidney injury is associated with reversible platelet dysfunction in hospitalized patients with decompensated cirrhosis Digestive And Liver Disease 2020, 52: e13. DOI: 10.1016/j.dld.2019.12.031.
Effect of Loop Diuretics on the Fractional Excretion of Urea in Decompensated Heart FailureCox ZL, Sury K, Rao VS, Ivey-Miranda JB, Griffin M, Mahoney D, Gomez N, Fleming JH, Inker LA, Coca SG, Turner J, Wilson FP, Testani JM. Effect of Loop Diuretics on the Fractional Excretion of Urea in Decompensated Heart Failure Journal Of Cardiac Failure 2020, 26: 402-409. PMID: 32007554, PMCID: PMC7798124, DOI: 10.1016/j.cardfail.2020.01.019.
First-in-Human Experience With Peritoneal Direct Sodium Removal Using a Zero-Sodium SolutionRao VS, Turner JM, Griffin M, Mahoney D, Asher J, Jeon S, Yoo PS, Boutagy N, Feher A, Sinusas A, Wilson FP, Finkelstein F, Testani JM. First-in-Human Experience With Peritoneal Direct Sodium Removal Using a Zero-Sodium Solution Circulation 2020, 141: 1043-1053. PMID: 31910658, PMCID: PMC7331276, DOI: 10.1161/circulationaha.119.043062.
Community Health Care Quality Standards to Prevent Acute Kidney Injury and Its ConsequencesSilver SA, Nadim MK, O'Donoghue DJ, Wilson FP, Kellum JA, Mehta RL, Ronco C, Kashani K, Rosner MH, Haase M, Lewington A. Community Health Care Quality Standards to Prevent Acute Kidney Injury and Its Consequences The American Journal Of Medicine 2019, 133: 552-560.e3. PMID: 31830434, PMCID: PMC7724764, DOI: 10.1016/j.amjmed.2019.10.038.
Clinical Implications of the New York Heart Association ClassificationCaraballo C, Desai NR, Mulder H, Alhanti B, Wilson FP, Fiuzat M, Felker GM, Piña IL, O'Connor CM, Lindenfeld J, Januzzi JL, Cohen LS, Ahmad T. Clinical Implications of the New York Heart Association Classification Journal Of The American Heart Association 2019, 8: e014240. PMID: 31771438, PMCID: PMC6912957, DOI: 10.1161/jaha.119.014240.
Quantifying Donor Effects on Transplant Outcomes Using Kidney Pairs from Deceased Donors.Kerr KF, Morenz ER, Thiessen-Philbrook H, Coca SG, Wilson FP, Reese PP, Parikh CR. Quantifying Donor Effects on Transplant Outcomes Using Kidney Pairs from Deceased Donors. Clinical Journal Of The American Society Of Nephrology 2019, 14: 1781-1787. PMID: 31676539, PMCID: PMC6895487, DOI: 10.2215/cjn.03810319.
Development and Validation of a Model for Predicting the Risk of Acute Kidney Injury Associated With Contrast Volume Levels During Percutaneous Coronary InterventionHuang C, Li SX, Mahajan S, Testani JM, Wilson FP, Mena CI, Masoudi FA, Rumsfeld JS, Spertus JA, Mortazavi BJ, Krumholz HM. Development and Validation of a Model for Predicting the Risk of Acute Kidney Injury Associated With Contrast Volume Levels During Percutaneous Coronary Intervention JAMA Network Open 2019, 2: e1916021. PMID: 31755952, PMCID: PMC6902830, DOI: 10.1001/jamanetworkopen.2019.16021.
Machine Learning to Predict Acute Kidney InjuryWilson FP. Machine Learning to Predict Acute Kidney Injury American Journal Of Kidney Diseases 2019, 75: 965-967. PMID: 31677894, PMCID: PMC7735021, DOI: 10.1053/j.ajkd.2019.08.010.
Association of T Cell–Derived Inflammatory Cytokines With Acute Kidney Injury and Mortality After Cardiac SurgeryMoledina DG, Mansour SG, Jia Y, Obeid W, Thiessen-Philbrook H, Koyner JL, McArthur E, Garg AX, Wilson FP, Shlipak MG, Coca SG, Parikh CR, Consortium T. Association of T Cell–Derived Inflammatory Cytokines With Acute Kidney Injury and Mortality After Cardiac Surgery Kidney International Reports 2019, 4: 1689-1697. PMID: 31844805, PMCID: PMC6895592, DOI: 10.1016/j.ekir.2019.09.003.
Effect on Survival of Concurrent Hemoconcentration and Increase in Creatinine During Treatment of Acute Decompensated Heart FailureGriffin M, Rao VS, Fleming J, Raghavendra P, Turner J, Mahoney D, Wettersten N, Maisel A, Ivey-Miranda JB, Inker L, Tang WHW, Wilson FP, Testani JM. Effect on Survival of Concurrent Hemoconcentration and Increase in Creatinine During Treatment of Acute Decompensated Heart Failure The American Journal Of Cardiology 2019, 124: 1707-1711. PMID: 31601358, PMCID: PMC6959849, DOI: 10.1016/j.amjcard.2019.08.034.
Patient-Reported Outcome Measures for Adults With Kidney Disease: Current Measures, Ongoing Initiatives, and Future Opportunities for Incorporation Into Patient-Centered Kidney CareNair D, Wilson FP. Patient-Reported Outcome Measures for Adults With Kidney Disease: Current Measures, Ongoing Initiatives, and Future Opportunities for Incorporation Into Patient-Centered Kidney Care American Journal Of Kidney Diseases 2019, 74: 791-802. PMID: 31492487, PMCID: PMC6875620, DOI: 10.1053/j.ajkd.2019.05.025.
A simple real-time model for predicting acute kidney injury in hospitalized patients in the US: A descriptive modeling studySimonov M, Ugwuowo U, Moreira E, Yamamoto Y, Biswas A, Martin M, Testani J, Wilson FP. A simple real-time model for predicting acute kidney injury in hospitalized patients in the US: A descriptive modeling study PLOS Medicine 2019, 16: e1002861. PMID: 31306408, PMCID: PMC6629054, DOI: 10.1371/journal.pmed.1002861.
Renal Effects of Intensive Volume Removal in Heart Failure Patients With Preexisting Worsening Renal FunctionRao VS, Ahmad T, Brisco-Bacik MA, Bonventre JV, Wilson FP, Siew ED, Felker GM, Anstrom KK, Mahoney DD, Bart BA, Tang WHW, Velazquez EJ, Testani JM. Renal Effects of Intensive Volume Removal in Heart Failure Patients With Preexisting Worsening Renal Function Circulation Heart Failure 2019, 12: e005552. PMID: 31163974, PMCID: PMC6585463, DOI: 10.1161/circheartfailure.118.005552.
Research-based versus clinical serum creatinine measurements and the association of acute kidney injury with subsequent kidney function: findings from the Chronic Renal Insufficiency Cohort studyHsu RK, Hsu CY, McCulloch CE, Yang J, Anderson AH, Chen J, Feldman HI, He J, Liu KD, Navaneethan SD, Porter AC, Rahman M, Tan TC, Wilson FP, Xie D, Zhang X, Go AS, Appel L, Kusek J, Lash J, Rao P, Townsend R. Research-based versus clinical serum creatinine measurements and the association of acute kidney injury with subsequent kidney function: findings from the Chronic Renal Insufficiency Cohort study Clinical Kidney Journal 2019, 13: 55-62. PMID: 32082553, PMCID: PMC7025351, DOI: 10.1093/ckj/sfz057.
Quality Improvement Goals for Acute Kidney InjuryKashani K, Rosner MH, Haase M, Lewington AJP, O'Donoghue DJ, Wilson FP, Nadim MK, Silver SA, Zarbock A, Ostermann M, Mehta RL, Kane-Gill SL, Ding X, Pickkers P, Bihorac A, Siew ED, Barreto EF, Macedo E, Kellum JA, Palevsky PM, Tolwani AJ, Ronco C, Juncos LA, Rewa OG, Bagshaw SM, Mottes TA, Koyner JL, Liu KD, Forni LG, Heung M, Wu VC. Quality Improvement Goals for Acute Kidney Injury Clinical Journal Of The American Society Of Nephrology 2019, 14: 941-953. PMID: 31101671, PMCID: PMC6556737, DOI: 10.2215/cjn.01250119.
Urine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritisMoledina DG, Wilson FP, Pober JS, Perazella MA, Singh N, Luciano RL, Obeid W, Lin H, Kuperman M, Moeckel GW, Kashgarian M, Cantley LG, Parikh CR. Urine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritis JCI Insight 2019, 4: e127456. PMID: 31092735, PMCID: PMC6542610, DOI: 10.1172/jci.insight.127456.
Electronic Alerts for Acute Kidney Injury Amelioration (ELAIA-1): a completely electronic, multicentre, randomised controlled trial: design and rationaleMutter M, Martin M, Yamamoto Y, Biswas A, Etropolski B, Feldman H, Garg A, Gourlie N, Latham S, Lin H, Palevsky PM, Parikh C, Moreira E, Ugwuowo U, Wilson FP. Electronic Alerts for Acute Kidney Injury Amelioration (ELAIA-1): a completely electronic, multicentre, randomised controlled trial: design and rationale BMJ Open 2019, 9: e025117. PMID: 31154298, PMCID: PMC6549649, DOI: 10.1136/bmjopen-2018-025117.
Natriuretic Response Is Highly Variable and Associated With 6-Month Survival Insights From the ROSE-AHF TrialHodson DZ, Griffin M, Mahoney D, Raghavendra P, Ahmad T, Turner J, Wilson FP, Tang WHW, Rao VS, Collins SP, Mullens W, Testani JM. Natriuretic Response Is Highly Variable and Associated With 6-Month Survival Insights From the ROSE-AHF Trial JACC Heart Failure 2019, 7: 383-391. PMID: 31047017, PMCID: PMC6501816, DOI: 10.1016/j.jchf.2019.01.007.
Serum and Urine Albumin and Response to Loop Diuretics in Heart FailureCharokopos A, Griffin M, Rao VS, Inker L, Sury K, Asher J, Turner J, Mahoney D, Cox ZL, Wilson FP, Testani JM. Serum and Urine Albumin and Response to Loop Diuretics in Heart Failure Clinical Journal Of The American Society Of Nephrology 2019, 14: cjn.11600918. PMID: 31010938, PMCID: PMC6500945, DOI: 10.2215/cjn.11600918.
Coupling growth kinetics modeling with machine learning reveals microbial immigration impacts and identifies key environmental parameters in a biological wastewater treatment process.Mei R, Kim J, Wilson FP, Bocher BTW, Liu WT. Coupling growth kinetics modeling with machine learning reveals microbial immigration impacts and identifies key environmental parameters in a biological wastewater treatment process. Microbiome 2019, 7: 65. PMID: 30995941, PMCID: PMC6471889, DOI: 10.1186/s40168-019-0682-x.
The Association of Angiogenesis Markers With Acute Kidney Injury and Mortality After Cardiac SurgeryMansour SG, Zhang WR, Moledina D, Coca SG, Jia Y, Thiessen-Philbrook H, McArthur E, Inoue K, Koyner JL, Shlipak MG, Wilson FP, Garg AX, Ishibe S, Parikh CR, Consortium T. The Association of Angiogenesis Markers With Acute Kidney Injury and Mortality After Cardiac Surgery American Journal Of Kidney Diseases 2019, 74: 36-46. PMID: 30955944, PMCID: PMC6591032, DOI: 10.1053/j.ajkd.2019.01.028.
Insulin resistance and chronic kidney disease progression, cardiovascular events, and death: findings from the chronic renal insufficiency cohort studySchrauben SJ, Jepson C, Hsu JY, Wilson FP, Zhang X, Lash JP, Robinson BM, Townsend RR, Chen J, Fogelfeld L, Kao P, Landis JR, Rader DJ, Hamm LL, Anderson AH, Feldman HI. Insulin resistance and chronic kidney disease progression, cardiovascular events, and death: findings from the chronic renal insufficiency cohort study BMC Nephrology 2019, 20: 60. PMID: 30786864, PMCID: PMC6383235, DOI: 10.1186/s12882-019-1220-6.
Podocyte histone deacetylase activity regulates murine and human glomerular diseasesInoue K, Gan G, Ciarleglio M, Zhang Y, Tian X, Pedigo CE, Cavanaugh C, Tate J, Wang Y, Cross E, Groener M, Chai N, Wang Z, Justice A, Zhang Z, Parikh CR, Wilson FP, Ishibe S. Podocyte histone deacetylase activity regulates murine and human glomerular diseases Journal Of Clinical Investigation 2019, 129: 1295-1313. PMID: 30776024, PMCID: PMC6391095, DOI: 10.1172/jci124030.
Enhancing the prediction of acute kidney injury risk after percutaneous coronary intervention using machine learning techniques: A retrospective cohort studyHuang C, Murugiah K, Mahajan S, Li SX, Dhruva SS, Haimovich JS, Wang Y, Schulz WL, Testani JM, Wilson FP, Mena CI, Masoudi FA, Rumsfeld JS, Spertus JA, Mortazavi BJ, Krumholz HM. Enhancing the prediction of acute kidney injury risk after percutaneous coronary intervention using machine learning techniques: A retrospective cohort study PLOS Medicine 2018, 15: e1002703. PMID: 30481186, PMCID: PMC6258473, DOI: 10.1371/journal.pmed.1002703.
Kidney Biopsy–Related Complications in Hospitalized Patients with Acute Kidney DiseaseMoledina DG, Luciano RL, Kukova L, Chan L, Saha A, Nadkarni G, Alfano S, Wilson FP, Perazella MA, Parikh CR. Kidney Biopsy–Related Complications in Hospitalized Patients with Acute Kidney Disease Clinical Journal Of The American Society Of Nephrology 2018, 13: 1633-1640. PMID: 30348813, PMCID: PMC6237071, DOI: 10.2215/cjn.04910418.
Translational Methods in Nephrology: Individual Treatment Effect ModelingWilson FP, Parikh CR. Translational Methods in Nephrology: Individual Treatment Effect Modeling Journal Of The American Society Of Nephrology 2018, 29: asn.2018060629. PMID: 30279274, PMCID: PMC6218865, DOI: 10.1681/asn.2018060629.
Outcomes Associated With a Strategy of Adjuvant Metolazone or High‐Dose Loop Diuretics in Acute Decompensated Heart Failure: A Propensity AnalysisBrisco‐Bacik M, Maaten J, Houser SR, Vedage NA, Rao V, Ahmad T, Wilson FP, Testani JM. Outcomes Associated With a Strategy of Adjuvant Metolazone or High‐Dose Loop Diuretics in Acute Decompensated Heart Failure: A Propensity Analysis Journal Of The American Heart Association 2018, 7: e009149. PMID: 30371181, PMCID: PMC6222930, DOI: 10.1161/jaha.118.009149.
The Trifecta of Precision Care in Heart Failure Biology, Biomarkers, and Big Data ∗Ahmad T, Wilson FP, Desai NR. The Trifecta of Precision Care in Heart Failure Biology, Biomarkers, and Big Data ∗ Journal Of The American College Of Cardiology 2018, 72: 1091-1094. PMID: 30165979, PMCID: PMC6345377, DOI: 10.1016/j.jacc.2018.07.009.
Acute Kidney Injury in Real Time: Prediction, Alerts, and Clinical Decision SupportWilson FP, Greenberg JH. Acute Kidney Injury in Real Time: Prediction, Alerts, and Clinical Decision Support Nephron 2018, 140: 116-119. PMID: 30071528, PMCID: PMC6165685, DOI: 10.1159/000492064.
The Renal Effects of Aggressive Volume Removal in Heart Failure Patients with Preexisting Worsening Renal FunctionMahoney D, Ahmad T, Rao V, Brisco-Bacik M, Wilson F, Siew E, Felker G, Anstrom K, Bart B, Tang W, O'Connor C, Velazquez E, Testani J. The Renal Effects of Aggressive Volume Removal in Heart Failure Patients with Preexisting Worsening Renal Function Journal Of Cardiac Failure 2018, 24: s26. DOI: 10.1016/j.cardfail.2018.07.074.
Utility of Electronic Medical Record Alerts to Prevent Drug NephrotoxicityMartin M, Wilson FP. Utility of Electronic Medical Record Alerts to Prevent Drug Nephrotoxicity Clinical Journal Of The American Society Of Nephrology 2018, 14: 115-123. PMID: 29622668, PMCID: PMC6364537, DOI: 10.2215/cjn.13841217.
Identification of Patients Expected to Benefit from Electronic Alerts for Acute Kidney InjuryBiswas A, Parikh CR, Feldman HI, Garg AX, Latham S, Lin H, Palevsky PM, Ugwuowo U, Wilson FP. Identification of Patients Expected to Benefit from Electronic Alerts for Acute Kidney Injury Clinical Journal Of The American Society Of Nephrology 2018, 13: 842-849. PMID: 29599299, PMCID: PMC5989673, DOI: 10.2215/cjn.13351217.
Attributable Risk and Time Course of Colistin-Associated Acute Kidney InjuryMiano TA, Lautenbach E, Wilson FP, Guo W, Borovskiy Y, Hennessy S. Attributable Risk and Time Course of Colistin-Associated Acute Kidney Injury Clinical Journal Of The American Society Of Nephrology 2018, 13: 542-550. PMID: 29545383, PMCID: PMC5969457, DOI: 10.2215/cjn.06980717.
Biomarkers of AKI Progression after Pediatric Cardiac SurgeryGreenberg JH, Zappitelli M, Jia Y, Thiessen-Philbrook HR, de Fontnouvelle CA, Wilson FP, Coca S, Devarajan P, Parikh CR. Biomarkers of AKI Progression after Pediatric Cardiac Surgery Journal Of The American Society Of Nephrology 2018, 29: 1549-1556. PMID: 29472416, PMCID: PMC5967766, DOI: 10.1681/asn.2017090989.
Worsening Renal Function in Patients With Acute Heart Failure Undergoing Aggressive Diuresis Is Not Associated With Tubular InjuryAhmad T, Jackson K, Rao VS, Tang WHW, Brisco-Bacik MA, Chen HH, Felker GM, Hernandez AF, O'Connor CM, Sabbisetti VS, Bonventre JV, Wilson FP, Coca SG, Testani JM. Worsening Renal Function in Patients With Acute Heart Failure Undergoing Aggressive Diuresis Is Not Associated With Tubular Injury Circulation 2018, 137: 2016-2028. PMID: 29352071, PMCID: PMC6066176, DOI: 10.1161/circulationaha.117.030112.
Development of biomarker combinations for postoperative acute kidney injury via Bayesian model selection in a multicenter cohort studyMeisner A, Kerr KF, Thiessen-Philbrook H, Wilson FP, Garg AX, Shlipak MG, Kavsak P, Whitlock RP, Coca SG, Parikh CR. Development of biomarker combinations for postoperative acute kidney injury via Bayesian model selection in a multicenter cohort study Biomarker Research 2018, 6: 3. PMID: 29344362, PMCID: PMC5767010, DOI: 10.1186/s40364-018-0117-z.
Group analysis identifies differentially elevated biomarkers with distinct outcomes for advanced acute kidney injury in cardiac surgeryLin H, Scherzer R, Philbrook HT, Coca SG, Wilson FP, Garg AX, Shlipak MG, Parikh CR. Group analysis identifies differentially elevated biomarkers with distinct outcomes for advanced acute kidney injury in cardiac surgery Biomarkers In Medicine 2017, 11: 1091-1102. PMID: 29172665, PMCID: PMC5753615, DOI: 10.2217/bmm-2017-0060.
A Survey of Patient Attitudes Toward Participation in Biopsy-Based Kidney ResearchMoledina DG, Cheung B, Kukova L, Luciano RL, Peixoto AJ, Wilson FP, Alfano S, Parikh CR. A Survey of Patient Attitudes Toward Participation in Biopsy-Based Kidney Research Kidney International Reports 2017, 3: 412-416. PMID: 29725645, PMCID: PMC5932306, DOI: 10.1016/j.ekir.2017.11.008.
Inflammation and cardio‐renal interactions in heart failure: a potential role for interleukin‐6Hanberg JS, Rao VS, Ahmad T, Chunara Z, Mahoney D, Jackson K, Jacoby D, Chen M, Wilson FP, Tang WHW, Kakkar R, Testani JM. Inflammation and cardio‐renal interactions in heart failure: a potential role for interleukin‐6 European Journal Of Heart Failure 2017, 20: 933-934. PMID: 29024287, PMCID: PMC5895540, DOI: 10.1002/ejhf.963.
Performance of Serum Creatinine and Kidney Injury Biomarkers for Diagnosing Histologic Acute Tubular InjuryMoledina DG, Hall IE, Thiessen-Philbrook H, Reese PP, Weng FL, Schröppel B, Doshi MD, Wilson FP, Coca SG, Parikh CR. Performance of Serum Creatinine and Kidney Injury Biomarkers for Diagnosing Histologic Acute Tubular Injury American Journal Of Kidney Diseases 2017, 70: 807-816. PMID: 28844586, PMCID: PMC5701867, DOI: 10.1053/j.ajkd.2017.06.031.
Evaluating biomarkers for prognostic enrichment of clinical trialsKerr KF, Roth J, Zhu K, Thiessen-Philbrook H, Meisner A, Wilson FP, Coca S, Parikh CR. Evaluating biomarkers for prognostic enrichment of clinical trials Clinical Trials 2017, 14: 629-638. PMID: 28795578, PMCID: PMC5714681, DOI: 10.1177/1740774517723588.
147 The Increased Mortality Risk Associated with Metolazone in Acute Heart Failure is Mediated by Worsening Renal Function and Electrolyte DisturbancesBrisco-Bacik M, Maaten J, Vedage N, Wilson F, Testani J. 147 The Increased Mortality Risk Associated with Metolazone in Acute Heart Failure is Mediated by Worsening Renal Function and Electrolyte Disturbances Journal Of Cardiac Failure 2017, 23: s56. DOI: 10.1016/j.cardfail.2017.07.157.
005 Concurrent Worsening Renal Function and Hemoconcentration during the Treatment of Decompensated Heart Failure is Associated with Improved SurvivalGriffin M, Rao V, Mahoney D, Jackson K, Chunara Z, Hodson D, Thomas D, Tarleton C, Chen M, Jacoby D, Riello R, Ahmad T, Wilson F, Testani J. 005 Concurrent Worsening Renal Function and Hemoconcentration during the Treatment of Decompensated Heart Failure is Associated with Improved Survival Journal Of Cardiac Failure 2017, 23: s5. DOI: 10.1016/j.cardfail.2017.07.008.
Compensatory Distal Reabsorption Drives Diuretic Resistance in Human Heart FailureRao VS, Planavsky N, Hanberg JS, Ahmad T, Brisco-Bacik MA, Wilson FP, Jacoby D, Chen M, Tang WHW, Cherney DZI, Ellison DH, Testani JM. Compensatory Distal Reabsorption Drives Diuretic Resistance in Human Heart Failure Journal Of The American Society Of Nephrology 2017, 28: 3414-3424. PMID: 28739647, PMCID: PMC5661276, DOI: 10.1681/asn.2016111178.
Information Technology and Acute Kidney Injury: Alerts, Alarms, Bells, and WhistlesWilson FP. Information Technology and Acute Kidney Injury: Alerts, Alarms, Bells, and Whistles Advances In Chronic Kidney Disease 2017, 24: 241-245. PMID: 28778364, PMCID: PMC5650118, DOI: 10.1053/j.ackd.2017.05.007.
An exploratory analysis of the competing effects of aggressive decongestion and high-dose loop diuretic therapy in the DOSE trialHanberg JS, Tang WH, Wilson FP, Coca SG, Ahmad T, Brisco MA, Testani JM. An exploratory analysis of the competing effects of aggressive decongestion and high-dose loop diuretic therapy in the DOSE trial International Journal Of Cardiology 2017, 241: 277-282. PMID: 28392080, PMCID: PMC5471358, DOI: 10.1016/j.ijcard.2017.03.114.
Approaches to Predicting Outcomes in Patients with Acute Kidney InjurySaly D, Yang A, Triebwasser C, Oh J, Sun Q, Testani J, Parikh CR, Bia J, Biswas A, Stetson C, Chaisanguanthum K, Wilson FP. Approaches to Predicting Outcomes in Patients with Acute Kidney Injury PLOS ONE 2017, 12: e0169305. PMID: 28122032, PMCID: PMC5266278, DOI: 10.1371/journal.pone.0169305.
Renal tubular resistance is the primary driver for loop diuretic resistance in acute heart failureMaaten J, Rao VS, Hanberg JS, Wilson F, Bellumkonda L, Assefa M, Broughton J, D'Ambrosi J, Tang W, Damman K, Voors AA, Ellison DH, Testani JM. Renal tubular resistance is the primary driver for loop diuretic resistance in acute heart failure European Journal Of Heart Failure 2017, 19: 1014-1022. PMID: 28105769, PMCID: PMC6231236, DOI: 10.1002/ejhf.757.
Association between e-alert implementation for detection of acute kidney injury and outcomes: a systematic reviewLachance P, Villeneuve PM, Rewa OG, Wilson FP, Selby NM, Featherstone RM, Bagshaw SM. Association between e-alert implementation for detection of acute kidney injury and outcomes: a systematic review Nephrology Dialysis Transplantation 2017, 32: 265-272. PMID: 28088774, PMCID: PMC6251638, DOI: 10.1093/ndt/gfw424.
Association of Alternative Approaches to Normalizing Peritoneal Dialysis Clearance with Mortality and Technique Failure: A Retrospective Analysis Using the United States Renal Data System-Dialysis Morbidity and Mortality Study, Wave 2Boyle SM, Li Y, Wilson FP, Glickman JD, Feldman HI. Association of Alternative Approaches to Normalizing Peritoneal Dialysis Clearance with Mortality and Technique Failure: A Retrospective Analysis Using the United States Renal Data System-Dialysis Morbidity and Mortality Study, Wave 2 Advances In Peritoneal Dialysis 2017, 37: 85-93. PMID: 27680757, PMCID: PMC5448711, DOI: 10.3747/pdi.2015.00227.
Lifetime Probabilities of ESRD: A Decade of DisparityGrams ME, Wilson FP. Lifetime Probabilities of ESRD: A Decade of Disparity American Journal Of Kidney Diseases 2016, 68: 831-832. PMID: 27884278, DOI: 10.1053/j.ajkd.2016.09.006.
Urine biomarkers of tubular injury do not improve on the clinical model predicting chronic kidney disease progressionHsu CY, Xie D, Waikar SS, Bonventre JV, Zhang X, Sabbisetti V, Mifflin TE, Coresh J, Diamantidis CJ, He J, Lora CM, Miller ER, Nelson RG, Ojo AO, Rahman M, Schelling JR, Wilson FP, Kimmel PL, Feldman HI, Vasan RS, Liu KD, Investigators C, Appel L, Feldman H, Go A, He J, Kusek J, Lash J, Ojo A, Rahman M, Townsend R, Consortium C. Urine biomarkers of tubular injury do not improve on the clinical model predicting chronic kidney disease progression Kidney International 2016, 91: 196-203. PMID: 28029431, PMCID: PMC5362331, DOI: 10.1016/j.kint.2016.09.003.
Hypochloremia and Diuretic Resistance in Heart FailureHanberg JS, Rao V, Maaten J, Laur O, Brisco MA, Wilson F, Grodin JL, Assefa M, Broughton J, Planavsky NJ, Ahmad T, Bellumkonda L, Tang WH, Parikh CR, Testani JM. Hypochloremia and Diuretic Resistance in Heart Failure Circulation Heart Failure 2016, 9: e003180. PMID: 27507113, PMCID: PMC4988527, DOI: 10.1161/circheartfailure.116.003180.
160 Association of Loop Diuretic Dose with Readmission and Survival in Patients Receiving Protocol Driven Titration of Loop DiureticsBellumkonda L, Hanberg J, Assefa M, Broughton S, Wilson F, Ahmad T, Testani J. 160 Association of Loop Diuretic Dose with Readmission and Survival in Patients Receiving Protocol Driven Titration of Loop Diuretics Journal Of Cardiac Failure 2016, 22: s59-s60. DOI: 10.1016/j.cardfail.2016.06.180.
Preventing acute kidney injury through nephrotoxin managementPerazella MA, Wilson FP. Preventing acute kidney injury through nephrotoxin management Nature Reviews Nephrology 2016, 12: 511-512. PMID: 27374917, DOI: 10.1038/nrneph.2016.95.
Relevance of Changes in Serum Creatinine During a Heart Failure Trial of Decongestive Strategies: Insights From the DOSE TrialBrisco MA, Zile MR, Hanberg JS, Wilson FP, Parikh CR, Coca SG, Tang WH, Testani JM. Relevance of Changes in Serum Creatinine During a Heart Failure Trial of Decongestive Strategies: Insights From the DOSE Trial Journal Of Cardiac Failure 2016, 22: 753-760. PMID: 27374839, PMCID: PMC5435117, DOI: 10.1016/j.cardfail.2016.06.423.
Provider acceptance of an automated electronic alert for acute kidney injuryOh J, Bia JR, Ubaid-Ullah M, Testani JM, Wilson FP. Provider acceptance of an automated electronic alert for acute kidney injury Clinical Kidney Journal 2016, 9: 567-571. PMID: 27478598, PMCID: PMC4957729, DOI: 10.1093/ckj/sfw054.
Impact of e-alert for detection of acute kidney injury on processes of care and outcomes: protocol for a systematic review and meta-analysisLachance P, Villeneuve PM, Wilson FP, Selby NM, Featherstone R, Rewa O, Bagshaw SM. Impact of e-alert for detection of acute kidney injury on processes of care and outcomes: protocol for a systematic review and meta-analysis BMJ Open 2016, 6: e011152. PMID: 27150187, PMCID: PMC4861089, DOI: 10.1136/bmjopen-2016-011152.
Reduced Cardiac Index Is Not the Dominant Driver of Renal Dysfunction in Heart FailureHanberg JS, Sury K, Wilson FP, Brisco MA, Ahmad T, Maaten J, Broughton JS, Assefa M, Tang WH, Parikh CR, Testani JM. Reduced Cardiac Index Is Not the Dominant Driver of Renal Dysfunction in Heart Failure Journal Of The American College Of Cardiology 2016, 67: 2199-2208. PMID: 27173030, PMCID: PMC4867078, DOI: 10.1016/j.jacc.2016.02.058.
The risk of death associated with proteinuria in heart failure is restricted to patients with an elevated blood urea nitrogen to creatinine ratioBrisco MA, Zile MR, Maaten J, Hanberg JS, Wilson FP, Parikh C, Testani JM. The risk of death associated with proteinuria in heart failure is restricted to patients with an elevated blood urea nitrogen to creatinine ratio International Journal Of Cardiology 2016, 215: 521-526. PMID: 27153048, PMCID: PMC4986924, DOI: 10.1016/j.ijcard.2016.04.100.
Clinical Implications of Cluster Analysis-Based Classification of Acute Decompensated Heart Failure and Correlation with Bedside Hemodynamic ProfilesAhmad T, Desai N, Wilson F, Schulte P, Dunning A, Jacoby D, Allen L, Fiuzat M, Rogers J, Felker GM, O’Connor C, Patel CB. Clinical Implications of Cluster Analysis-Based Classification of Acute Decompensated Heart Failure and Correlation with Bedside Hemodynamic Profiles PLOS ONE 2016, 11: e0145881. PMID: 26840410, PMCID: PMC4739604, DOI: 10.1371/journal.pone.0145881.
Proton Pump Inhibitor Use and the Risk of Chronic Kidney DiseaseLazarus B, Chen Y, Wilson FP, Sang Y, Chang AR, Coresh J, Grams ME. Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease JAMA Internal Medicine 2016, 176: 238-246. PMID: 26752337, PMCID: PMC4772730, DOI: 10.1001/jamainternmed.2015.7193.
Hypochloraemia is strongly and independently associated with mortality in patients with chronic heart failureTestani JM, Hanberg JS, Arroyo JP, Brisco MA, Ter Maaten JM, Wilson FP, Bellumkonda L, Jacoby D, Tang WH, Parikh CR. Hypochloraemia is strongly and independently associated with mortality in patients with chronic heart failure European Journal Of Heart Failure 2016, 18: 660-668. PMID: 26763893, PMCID: PMC5471359, DOI: 10.1002/ejhf.477.
Impact of electronic-alerting of acute kidney injury: workgroup statements from the 15th ADQI Consensus ConferenceHoste EA, Kashani K, Gibney N, Wilson FP, Ronco C, Goldstein SL, Kellum JA, Bagshaw SM, on behalf of the 15 ADQI Consensus Group. Impact of electronic-alerting of acute kidney injury: workgroup statements from the 15th ADQI Consensus Conference Canadian Journal Of Kidney Health And Disease 2016, 3: 10. PMID: 26925246, PMCID: PMC4768416, DOI: 10.1186/s40697-016-0101-1.
Rapid and Highly Accurate Prediction of Poor Loop Diuretic Natriuretic Response in Patients With Heart FailureTestani JM, Hanberg JS, Cheng S, Rao V, Onyebeke C, Laur O, Kula A, Chen M, Wilson FP, Darlington A, Bellumkonda L, Jacoby D, Tang WH, Parikh CR. Rapid and Highly Accurate Prediction of Poor Loop Diuretic Natriuretic Response in Patients With Heart Failure Circulation Heart Failure 2016, 9: e002370. PMID: 26721915, PMCID: PMC4741370, DOI: 10.1161/circheartfailure.115.002370.
Influence of Titration of Neurohormonal Antagonists and Blood Pressure Reduction on Renal Function and Decongestion in Decompensated Heart FailureKula AJ, Hanberg JS, Wilson FP, Brisco MA, Bellumkonda L, Jacoby D, Coca SG, Parikh CR, Tang WHW, Testani JM. Influence of Titration of Neurohormonal Antagonists and Blood Pressure Reduction on Renal Function and Decongestion in Decompensated Heart Failure Circulation Heart Failure 2015, 9: e002333. PMID: 26699390, PMCID: PMC4741376, DOI: 10.1161/circheartfailure.115.002333.
False-Positive Rate of AKI Using Consensus Creatinine–Based CriteriaLin J, Fernandez H, Shashaty MG, Negoianu D, Testani JM, Berns JS, Parikh CR, Wilson FP. False-Positive Rate of AKI Using Consensus Creatinine–Based Criteria Clinical Journal Of The American Society Of Nephrology 2015, 10: 1723-1731. PMID: 26336912, PMCID: PMC4594067, DOI: 10.2215/cjn.02430315.
Relation of atherogenic lipoproteins with estimated glomerular filtration rate decline: a longitudinal studyLin J, Khetarpal SA, Terembula K, Reilly MP, Wilson FP. Relation of atherogenic lipoproteins with estimated glomerular filtration rate decline: a longitudinal study BMC Nephrology 2015, 16: 130. PMID: 26238454, PMCID: PMC4545861, DOI: 10.1186/s12882-015-0122-5.
Drugs, Dialysis, Decisions, and Data: A Walk through the Minefield of NephropharmacologyWilson F, Nolin T, Berns J. Drugs, Dialysis, Decisions, and Data: A Walk through the Minefield of Nephropharmacology Seminars In Dialysis 2015, 28: 323-324. PMID: 25929704, DOI: 10.1111/sdi.12390.
Pharmacologic Treatment of Common Symptoms in Dialysis Patients: A Narrative ReviewMoledina DG, Perry Wilson F. Pharmacologic Treatment of Common Symptoms in Dialysis Patients: A Narrative Review Seminars In Dialysis 2015, 28: 377-383. PMID: 25913502, DOI: 10.1111/sdi.12378.
Automated, electronic alerts for acute kidney injury: a single-blind, parallel-group, randomised controlled trialWilson FP, Shashaty M, Testani J, Aqeel I, Borovskiy Y, Ellenberg SS, Feldman HI, Fernandez H, Gitelman Y, Lin J, Negoianu D, Parikh CR, Reese PP, Urbani R, Fuchs B. Automated, electronic alerts for acute kidney injury: a single-blind, parallel-group, randomised controlled trial The Lancet 2015, 385: 1966-1974. PMID: 25726515, PMCID: PMC4475457, DOI: 10.1016/s0140-6736(15)60266-5.
Demographics of Kidney Disease.Wilson FP. Eds Skorecki K, Chertow GM, Marsden PA, Tall MW, Yu ASL. Brenner & Rector: The Kidney. Elsevier, Philadelphia PA 19103, 2015.
Plasma Lipoprotein(a) Levels Are Associated with Mild Renal Impairment in Type 2 Diabetics Independent of AlbuminuriaLin J, Reilly MP, Terembula K, Wilson FP. Plasma Lipoprotein(a) Levels Are Associated with Mild Renal Impairment in Type 2 Diabetics Independent of Albuminuria PLOS ONE 2014, 9: e114397. PMID: 25490096, PMCID: PMC4260843, DOI: 10.1371/journal.pone.0114397.
Kidney Transplant Outcomes for Prior Living Organ DonorsPotluri V, Harhay MN, Wilson FP, Bloom RD, Reese PP. Kidney Transplant Outcomes for Prior Living Organ Donors Journal Of The American Society Of Nephrology 2014, 26: 1188-1194. PMID: 25412818, PMCID: PMC4413763, DOI: 10.1681/asn.2014030302.
Urinary Creatinine Excretion, Bioelectrical Impedance Analysis, and Clinical Outcomes in Patients with CKD: The CRIC StudyWilson FP, Xie D, Anderson AH, Leonard MB, Reese PP, Delafontaine P, Horwitz E, Kallem R, Navaneethan S, Ojo A, Porter AC, Sondheimer JH, Sweeney HL, Townsend RR, Feldman HI, Investigators T. Urinary Creatinine Excretion, Bioelectrical Impedance Analysis, and Clinical Outcomes in Patients with CKD: The CRIC Study Clinical Journal Of The American Society Of Nephrology 2014, 9: 2095-2103. PMID: 25381342, PMCID: PMC4255402, DOI: 10.2215/cjn.03790414.
A Policy of Preemption: The Timing of Renal Replacement Therapy in AKIWilson FP. A Policy of Preemption: The Timing of Renal Replacement Therapy in AKI Clinical Journal Of The American Society Of Nephrology 2014, 9: 1510-1512. PMID: 25107949, PMCID: PMC4152811, DOI: 10.2215/cjn.07210714.
A trial of in-hospital, electronic alerts for acute kidney injury: Design and rationaleWilson FP, Reese PP, Shashaty MG, Ellenberg SS, Gitelman Y, Bansal AD, Urbani R, Feldman HI, Fuchs B. A trial of in-hospital, electronic alerts for acute kidney injury: Design and rationale Clinical Trials 2014, 11: 521-529. PMID: 25023200, PMCID: PMC4156885, DOI: 10.1177/1740774514542619.
Dialysis versus Nondialysis in Patients with AKI: A Propensity-Matched Cohort StudyWilson FP, Yang W, Machado CA, Mariani LH, Borovskiy Y, Berns JS, Feldman HI. Dialysis versus Nondialysis in Patients with AKI: A Propensity-Matched Cohort Study Clinical Journal Of The American Society Of Nephrology 2014, 9: 673-681. PMID: 24651073, PMCID: PMC3974360, DOI: 10.2215/cjn.07630713.
Tumor Lysis Syndrome: New Challenges and Recent AdvancesWilson FP, Berns JS. Tumor Lysis Syndrome: New Challenges and Recent Advances Advances In Chronic Kidney Disease 2014, 21: 18-26. PMID: 24359983, PMCID: PMC4017246, DOI: 10.1053/j.ackd.2013.07.001.
Electrolyte Disorders.Wilson FP. Eds Lanken PN, Manaker S, Kohl BA, Hanson CW. The Intensive Care Unit Manual. Elsevier, Philadelphia, PA 19103, 2014, PP 389-399
Renal Physiology and PathophysiologyWilson FP. Ed Hanno PM, Guzzo TJ, Malkowicz SB, Wein AJ. Penn Clinical Manual of Urology; Expert Consult. Elsevier, Philadelphia, PA 19103, 2014, PP732.
Determinants of surgical decision making: a national surveyWilson NP, Wilson FP, Neuman M, Epstein A, Bell R, Armstrong K, Murayama K. Determinants of surgical decision making: a national survey The American Journal Of Surgery 2013, 206: 970-978. PMID: 24296100, PMCID: PMC4017239, DOI: 10.1016/j.amjsurg.2013.08.018.
The impact of documentation of severe acute kidney injury on mortalityWilson FP, Bansal AD, Jasti SK, Lin JJ, Shashaty MG, Berns JS, Feldman HI, Fuchs BD. The impact of documentation of severe acute kidney injury on mortality Clinical Nephrology 2013, 80: 417-425. PMID: 24075024, PMCID: PMC4018223, DOI: 10.5414/cn108072.
Sundays and Mortality in Patients with AKIWilson FP, Yang W, Schrauben S, Machado C, Lin JJ, Feldman HI. Sundays and Mortality in Patients with AKI Clinical Journal Of The American Society Of Nephrology 2013, 8: 1863-1869. PMID: 23970128, PMCID: PMC3817908, DOI: 10.2215/cjn.03540413.
Cdc42 Deficiency Causes Ciliary Abnormalities and Cystic KidneysChoi SY, Chacon-Heszele MF, Huang L, McKenna S, Wilson FP, Zuo X, Lipschutz JH. Cdc42 Deficiency Causes Ciliary Abnormalities and Cystic Kidneys Journal Of The American Society Of Nephrology 2013, 24: 1435-1450. PMID: 23766535, PMCID: PMC3752951, DOI: 10.1681/asn.2012121236.
Predictors of Death and Dialysis in Severe AKI: The UPHS-AKI CohortWilson FP, Yang W, Feldman HI. Predictors of Death and Dialysis in Severe AKI: The UPHS-AKI Cohort Clinical Journal Of The American Society Of Nephrology 2012, 8: 527-537. PMID: 23258795, PMCID: PMC3613955, DOI: 10.2215/cjn.06450612.
Onco-Nephrology: Tumor Lysis SyndromeWilson FP, Berns JS. Onco-Nephrology: Tumor Lysis Syndrome Clinical Journal Of The American Society Of Nephrology 2012, 7: 1730-1739. PMID: 22879434, DOI: 10.2215/cjn.03150312.
Low Cefepime Concentrations during High Blood and Dialysate Flow Continuous Venovenous HemodialysisWilson FP, Bachhuber MA, Caroff D, Adler R, Fish D, Berns J. Low Cefepime Concentrations during High Blood and Dialysate Flow Continuous Venovenous Hemodialysis Antimicrobial Agents And Chemotherapy 2012, 56: 2178-2180. PMID: 22290968, PMCID: PMC3318326, DOI: 10.1128/aac.05987-11.
Creatinine generation is reduced in patients requiring continuous venovenous hemodialysis and independently predicts mortalityWilson FP, Sheehan JM, Mariani LH, Berns JS. Creatinine generation is reduced in patients requiring continuous venovenous hemodialysis and independently predicts mortality Nephrology Dialysis Transplantation 2012, 27: 4088-4094. PMID: 22273668, PMCID: PMC3529547, DOI: 10.1093/ndt/gfr809.
Multiple Chapters.Wilson FP. Eds Berns JS, Lerma E. Current Essentials of Diagnosis & Treatment in Nephrology and Hypertenstion. McGraw-Hill, New York. 2012.
Vancomycin levels are frequently subtherapeutic during continuous venovenous hemodialysis (CVVHD)Wilson FP, Berns JS. Vancomycin levels are frequently subtherapeutic during continuous venovenous hemodialysis (CVVHD) Clinical Nephrology 2011, 77: 329-331. PMID: 22445477, PMCID: PMC3359699, DOI: 10.5414/cn106993.
A destructive nasal lesion and glomerulonephritisWilson FP, Nasr SH, Markowitz GS, Naylor EC, Sterman PL, D'Agati VD. A destructive nasal lesion and glomerulonephritis Kidney International 2006, 69: 1699-1703. PMID: 16508654, DOI: 10.1038/sj.ki.5000282.
A Story that Illustrates Humanism in Medicine: Garlic Every Day, and Other WisdomWilson FP. A Story that Illustrates Humanism in Medicine: Garlic Every Day, and Other Wisdom Academic Medicine 2004, 79: 1206-1207. PMID: 15563658, DOI: 10.1097/00001888-200412000-00017.

Clinical Trials

Conditions	Study Title
Diseases of the Cardiovascular System	Pragmatic Trial Of Alerts for Use of Mineralocorticoid Receptor Antagonists (PROMPT-MRA)
Diseases of the Cardiovascular System	The WARN Study

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F. Perry Wilson, MD, MSCE

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