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F. Perry Wilson, MD, MSCE

Associate Professor Term; Director, Clinical and Translational Research Accelerator (CTRA); Course Director, Interpretation of the Medical Literature; Co Director, Human Genetics and Clinical Research Core

Research Summary

Dr. Wilson's research focuses on real-time analytics and interventions to prevent and treat acute kidney injury and chronic kidney disease. He has a particular interest in the development and application of personalized medicine techniques to target the proper therapy to the proper patient. He pursues interventional studies to try to help patients live longer, happier lives.

Specialized Terms: Randomized Trials; Acute Kidney Injury; Disparities; Outcomes; CKD progression; Machine-Learning; Personalized Medicine; Uplift modeling.

Extensive Research Description

Dr. Wilson uses epidemiologic and translational research methods to characterize predictors of outcomes in patients with both chronic kidney disease and acute kidney injury. In addition, he uses advanced machine-learning techniques to identify which patients are most likely to respond to a given intervention. These models can reduce the number of individuals exposed to a drug or intervention unnecessarily, reducing adverse events, and lowering costs.



Coauthors

Research Interests

Internal Medicine; Nephrology; Clinical Trial; Decision Support Systems, Clinical; Acute Kidney Injury; Machine Learning; Alert Fatigue, Health Personnel; Implementation Science

Public Health Interests

Epidemiology Methods; Pharmacoepidemiology

Selected Publications

Clinical Trials

ConditionsStudy Title
Diseases of the Cardiovascular SystemPragmatic Trial Of Alerts for Use of Mineralocorticoid Receptor Antagonists (PROMPT-MRA)
Diseases of the Cardiovascular SystemThe WARN Study