Eric B Schneider, PhD
Cards
About
Titles
Associate Professor of Surgery
Associate Professor on Term, Chronic Disease EpidemiologyBiography
Dr. Schneider earned both his undergraduate degree from Johns Hopkins University and his doctoral degree the Bloomberg School of Public Health at Johns Hopkins in Baltimore, MD. Prior to joining the faculty at Yale, Dr. Schneider served as Associate Professor of Surgery and Public Health Sciences and Vice Chair of Surgery for Health Services and Outcomes Research in the Department of Surgery at the University of Virginia in Charlottesville. He has served as a faculty member at the Johns Hopkins School of Medicine, Harvard Medical School/Brigham and Women’s Hospital, and The Ohio State University. He also holds adjunct faculty appointments at Johns Hopkins and the Uniformed Services University of the Health Sciences. He has served as a consultant to the World Health Organization focused on trauma and trauma care in multiple countries and served as the corresponding author for the World Journal of Surgery article entitled, “Implementation of the World Health Organization Trauma Care Checklist Program in 11 Centers Across Multiple Economic Strata: Effect on Care Process Measures.” He has also worked as a consultant and preceptor for the Karolinska Institutet examining the implementation of a program to promote institutional childbirth among socioeconomically disadvantaged women in Gujarat, India. He has presented his work at multiple international conferences, with a particular focus on India. He is the principal investigator at Yale for multiple research studies funded by the Department of Defense (DARPA, DHA, USUHS, etc.). Dr. Schneider has authored more than two hundred peer-reviewed publications in scientific journals and trains clinical residents and research fellows in the methods and practices of health services and outcomes research. He has mentored multiple undergraduate and graduate students and more than 40 post-doctoral research fellows, most of whom were physicians he has also mentored more than a dozen surgical faculty members early in their careers.
Appointments
Surgery
Associate Professor on TermPrimaryChronic Disease Epidemiology
Associate Professor on TermSecondary
Other Departments & Organizations
Education & Training
- PhD
- Johns Hopkins University (2009)
- BS
- Johns Hopkins University (2003)
Research
Publications
2024
Heterogeneous gene expression during early arteriovenous fistula remodeling suggests that downregulation of metabolism predicts adaptive venous remodeling
Ohashi Y, Protack C, Aoyagi Y, Gonzalez L, Thaxton C, Zhang W, Kano M, Bai H, Yatsula B, Alves R, Hoshina K, Schneider E, Long X, Perry R, Dardik A. Heterogeneous gene expression during early arteriovenous fistula remodeling suggests that downregulation of metabolism predicts adaptive venous remodeling. Scientific Reports 2024, 14: 13287. PMID: 38858395, PMCID: PMC11164895, DOI: 10.1038/s41598-024-64075-8.Peer-Reviewed Original ResearchConceptsGene expression patternsArteriovenous fistula groupArteriovenous fistulaExpression patternsHeterogeneous gene expressionGene expression changesOutcomes of arteriovenous fistulaVenous remodelingArteriovenous fistula maturationPostoperative day 7Reduce patient morbidityRNA sequencingUpregulation of metabolismBioinformatics analysisGene expressionDownregulation of metabolismMetabolic pathwaysExpression changesGenesAVF maturationAVF remodelingFistula creationC57BL/6 miceClinical outcomesPatient morbidityCommon Data Elements and Databases Essential for the Study of Musculoskeletal Injuries in Military Personnel
Juman L, Schneider E, Clifton D, Koehlmoos T. Common Data Elements and Databases Essential for the Study of Musculoskeletal Injuries in Military Personnel. Military Medicine 2024, usae241. PMID: 38771112, DOI: 10.1093/milmed/usae241.Peer-Reviewed Original ResearchMilitary Health SystemMusculoskeletal injuriesService membersData elementsMedical encountersMilitary Health System Data RepositoryInjury statisticsPrevent musculoskeletal injuriesMilitary personnelBranch of serviceInjury preventionHealth systemCommon Data ElementsCore data elementsCommon Procedural Terminology codesForce readinessMedical assessmentEnvironmental scanSnowball samplingProcedural Terminology codesEvidence-informed policy decisionsMedical conditionsDisease burdenDeployment statusActive engagement
2023
Emergent Applications of Machine Learning for Diagnosing and Managing Appendicitis: A State-of-the-Art Review
Bhandarkar S, Tsutsumi A, Schneider E, Ong C, Paredes L, Brackett A, Ahuja V. Emergent Applications of Machine Learning for Diagnosing and Managing Appendicitis: A State-of-the-Art Review. Surgical Infections 2023, 25: 7-18. PMID: 38150507, DOI: 10.1089/sur.2023.201.Peer-Reviewed Original ResearchArtificial intelligence toolsNew artificial intelligence toolsArtificial neural networkSupport vector machineMachine learning-based toolLearning-based toolIntelligence toolsMachine learningUse casesNeural networkVector machineRandom forestAverage accuracyNovel solutionMachineEmergent applicationsAlgorithmOptimal modelQueriesHigh operator dependencyArt reviewAccuracyToolNetworkOperator dependencyDiverticulitis in Older Adults: Is Cognitive Impairment Associated With Outcomes?
Kodadek L, Moore M, Canner J, Schneider E. Diverticulitis in Older Adults: Is Cognitive Impairment Associated With Outcomes? Journal Of Surgical Research 2023, 291: 359-366. PMID: 37506436, DOI: 10.1016/j.jss.2023.06.015.Peer-Reviewed Original ResearchConceptsColonic diverticulitisCognitive impairmentEmergency departmentOlder adultsHospital mortalityOperative interventionInpatient admissionsPrimary diagnosisMultivariable Poisson regression modelsNationwide Emergency Department SamplePrimary payer statusRetrospective cohort studyElixhauser Comorbidity IndexEmergency Department SampleComorbid cognitive impairmentPoisson regression modelsComorbidity indexComplicated diverticulitisCognitive impairment statusCohort studyED encountersPatient ageED carePayer statusRelative riskAn Evaluation of Sex-Based Differences in Surrogate Consent for Older Adults Undergoing Surgical Intervention
Nagarkatti N, Miller S, Ahuja V, Schneider E, Mohanty S, Kodadek L. An Evaluation of Sex-Based Differences in Surrogate Consent for Older Adults Undergoing Surgical Intervention. Journal Of Surgical Research 2023, 288: 246-251. PMID: 37030182, DOI: 10.1016/j.jss.2023.02.041.Peer-Reviewed Original ResearchConceptsPreoperative cognitive impairmentMale patientsCognitive impairmentSurrogate consentSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramSurgical Quality Improvement ProgramPatients age 65Preoperative cognitive statusQuality Improvement ProgramHigh rateSex-based differencesFemale patientsPatient sexSurgical interventionStratified analysisFacets of medicineAge 75American CollegePatientsAge 65Cognitive statusDescriptive studyOlder adultsAge categoriesArterial Diameter and Percentage of Monocytes are Sex-Dependent Predictors of Early Arteriovenous Fistula Maturation
Satam K, Setia O, Moore M, Schneider E, Chaar C, Dardik A. Arterial Diameter and Percentage of Monocytes are Sex-Dependent Predictors of Early Arteriovenous Fistula Maturation. Annals Of Vascular Surgery 2023, 93: 128-136. PMID: 36812979, PMCID: PMC10277224, DOI: 10.1016/j.avsg.2023.01.052.Peer-Reviewed Original ResearchConceptsFistula maturationArteriovenous fistula maturationArterial diameterArteriovenous fistulaFistula creationBrachial artery diameterPrimary arteriovenous fistulaPercentage of neutrophilsPeak systolic velocityPercentage of monocytesBrachial-cephalic fistulaElectronic medical recordsSex differencesFistula utilizationInferior patencyPostoperative ultrasoundUnassisted maturationYears postprocedureSingle centerArtery diameterArterial inflowArterial velocitySystolic velocityMedical recordsMonocyte percentagePalliative Care in a Pandemic: A Multicenter Cohort of Critically Ill Patients with Coronavirus Disease 2019
Kodadek L, Moore M, Miller S, Schneider E, Ahuja V, Maerz L, Davis K. Palliative Care in a Pandemic: A Multicenter Cohort of Critically Ill Patients with Coronavirus Disease 2019. Surgical Infections 2023, 24: 190-198. PMID: 36757283, PMCID: PMC10081705, DOI: 10.1089/sur.2022.377.Peer-Reviewed Original ResearchConceptsIntensive care unitPalliative careIll patientsCoronavirus disease 2019Life careClinical characteristicsMechanical ventilationDisease 2019Acute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSyndrome coronavirus 2 infectionCoronavirus 2 infectionPalliative care consultationPalliative care servicesCOVID-19Outcomes of interestHospital lengthAdult patientsComorbid diseasesDisease courseMulticenter cohortCare unitCare consultationsVaccination dataPatients
2022
Indoor Versus Outdoor: Does Occupational Sunlight Exposure Increase Melanoma Risk? A Systematic Review
Maduka R, Tai K, Gonsai R, DeWalt N, Chetty A, Brackett A, Olino K, Schneider E, Ahuja V. Indoor Versus Outdoor: Does Occupational Sunlight Exposure Increase Melanoma Risk? A Systematic Review. Journal Of Surgical Research 2022, 283: 274-281. PMID: 36423476, DOI: 10.1016/j.jss.2022.10.025.Peer-Reviewed Original ResearchConceptsCutaneous melanomaSystematic reviewOutdoor occupationsGrading of RecommendationsChronic occupational exposureRetrospective case controlInternational Prospective RegisterNew cancer casesMeta-Analyses (PRISMA) guidelinesPreferred Reporting ItemsInitial database searchFull-text screeningCutaneous melanoma developmentEvidence certaintyCohort studyScreening recommendationsCommon cancerRisk factorsStudy protocolProspective RegisterCase ascertainmentCancer casesOccupational exposureStudy qualityCase controlBlood-Based Biomarkers of Repetitive, Subconcussive Blast Overpressure Exposure in the Training Environment: A Pilot Study
Agoston D, McCullough J, Aniceto R, Lin I, Kamnaksh A, Eklund M, Graves W, Dunbar C, Engall J, Schneider E, Leonessa F, Duckworth J. Blood-Based Biomarkers of Repetitive, Subconcussive Blast Overpressure Exposure in the Training Environment: A Pilot Study. Neurotrauma Reports 2022, 3: 479-490. PMID: 36337080, PMCID: PMC9634979, DOI: 10.1089/neur.2022.0029.Peer-Reviewed Original ResearchTraumatic brain injuryMatrix metalloprotease-9Serum levelsClaudin-5Ubiquitin C-terminal hydrolase L1Pilot studyUnknown long-term effectsElevated autoantibody titersGlial fibrillary acidic proteinMild traumatic brain injuryElevated serum levelsBlood-based biomarkersAlpha 7 subunitChronic degenerative processMolecular changesFibrillary acidic proteinBlast overpressure exposureAutoantibody titersAutoimmune processVascular changesElevated titersBrain injuryLong-term effectsBlood samplesMetalloprotease-9Surrogate consent for surgery among older adult patients
Miller SM, Nagarkatti N, Ahuja V, Schneider EB, Mohanty S, Rosenthal RA, Kodadek LM. Surrogate consent for surgery among older adult patients. Surgery 2022, 172: 1748-1752. PMID: 36123180, DOI: 10.1016/j.surg.2022.08.015.Peer-Reviewed Original ResearchConceptsHalf of patientsCognitive impairmentSurrogate consentHigher comorbidity burdenOlder adult patientsComorbidity burdenPreoperative disabilityAdult patientsOlder patientsFemale patientsSurgical interventionElective proceduresSurgical proceduresHealth characteristicsAmerican CollegeDaily livingOwn consentPatientsOlder adultsImpairmentSurgeryConsentDescriptive analysisFurther researchDiagnosis