2024
The Impact of Cannabis Use Disorder on Critical Illness
Carr Z, Strand E. The Impact of Cannabis Use Disorder on Critical Illness. 2024, 95-105. DOI: 10.1007/978-3-031-67069-5_7.Peer-Reviewed Original ResearchIntensive care unitImpacts of cannabis use disordersCannabis use disorderManagement of patientsIntensive care managementIntensive care management of patientsChronic adverse effectsCannabis useClinical evidenceCare management of patientsBotanical cannabisCannabis usageCare unitUse disorderCannabisOrgan systemsAdverse effectsPatientsDownstream effectsIntensive care unit providersMedical careCare management
2023
Predictors of Failure to Rescue After Postoperative Respiratory Failure: A Retrospective Cohort Analysis of 13,047 Patients Using the ACS-NSQIP Dataset
Karamchandani K, Khorsand S, Ebeling C, Yan L, Nakonezny P, Carr Z. Predictors of Failure to Rescue After Postoperative Respiratory Failure: A Retrospective Cohort Analysis of 13,047 Patients Using the ACS-NSQIP Dataset. Journal Of Surgical Research 2023, 293: 482-489. PMID: 37827025, DOI: 10.1016/j.jss.2023.09.030.Peer-Reviewed Original ResearchConceptsPostoperative respiratory failurePredictors of failureDay of surgeryRespiratory failureNoncardiac surgeryNational Surgical Quality Improvement Project databaseSurgeons National Surgical Quality Improvement Project databaseMultiple logistic regression modelACS-NSQIP datasetsPreoperative prealbumin levelRetrospective cohort studyAnesthesiologists physical statusRetrospective cohort analysisLogistic regression modelsPreoperative ascitesPreoperative creatininePostoperative complicationsPrealbumin levelsCohort studyStudy cohortDisseminated cancerCohort analysisAmerican CollegePatientsPhysical status
2021
Persistent Postoperative Vasoplegia After Ureteronephrectomy Due To Suspected Intravesical Gemcitabine Toxicity
Yan L, Bohorquez MA, Carr ZJ. Persistent Postoperative Vasoplegia After Ureteronephrectomy Due To Suspected Intravesical Gemcitabine Toxicity. A&A Practice 2021, 15: e01537. PMID: 34695040, DOI: 10.1213/xaa.0000000000001537.Peer-Reviewed Case Reports and Technical NotesConceptsIntravesical adjuvant therapyPulmonary embolic phenomenaTreatment of patientsPotential adverse eventsPostoperative vasoplegiaRobotic nephroureterectomyVasopressor supportAdjuvant therapyPostoperative courseAdverse eventsEmbolic phenomenaSupportive managementResuscitative effortsAllergic reactionsCommon causeVasoplegiaGemcitabine toxicityGemcitabinePatientsUreteronephrectomyNephroureterectomyBleedingTherapyInfection
2019
Cardiovascular Collapse in a Patient With Parotid Abscess: Dangerous Cross Talk Between the Brain and Heart: A Case Report.
Owusu K, Stredny ES, Williamson G, Carr ZJ, Karamchandani K. Cardiovascular Collapse in a Patient With Parotid Abscess: Dangerous Cross Talk Between the Brain and Heart: A Case Report. A&A Practice 2019, 13: 281-283. PMID: 31385818, DOI: 10.1213/xaa.0000000000001056.Peer-Reviewed Case Reports and Technical NotesConceptsParotid abscessCardiovascular collapseTrigeminal neuralgiaTrigeminocardiac reflexPostsurgical neuropathic painSignificant hemodynamic perturbationsLife-threatening complicationsNeuropathic painSymptomatic bradycardiaCase reportHemodynamic perturbationsOtolaryngologic surgeryEarly diagnosisTimely treatmentAbscessComplicationsPatientsCross talkNeuralgiaBradycardiaPainSurgeryReflexCliniciansDiagnosisStroke prophylaxis in critically-ill patients with new-onset atrial fibrillation
Schoaps RS, Quintili A, Bonavia A, Carr ZJ, Lehman EB, Abendroth T, Karamchandani K. Stroke prophylaxis in critically-ill patients with new-onset atrial fibrillation. Journal Of Thrombosis And Thrombolysis 2019, 48: 394-399. PMID: 30963394, DOI: 10.1007/s11239-019-01854-5.Peer-Reviewed Original ResearchConceptsNew-onset atrial fibrillationCHA2DS2-VASc scoreOral anticoagulant therapyOral anticoagulantsIll patientsStroke prophylaxisAnticoagulant therapyHospital dischargeAtrial fibrillationEffective stroke prophylaxisOnset atrial fibrillationStroke/TIACongestive heart failureLong-term incidenceElectronic medical recordsEligible patientsICU survivorsAdult patientsHeart failureThromboembolic diseaseMedical recordsHigh incidencePatientsAnticoagulantsStudy periodPain management in trauma patients affected by the opioid epidemic: A narrative review.
Karamchandani K, Klick JC, Linskey Dougherty M, Bonavia A, Allen SR, Carr ZJ. Pain management in trauma patients affected by the opioid epidemic: A narrative review. Journal Of Trauma And Acute Care Surgery 2019, 87: 430-439. PMID: 30939572, DOI: 10.1097/ta.0000000000002292.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOpioid useTrauma patientsNarrative reviewPain managementChronic painOpioid epidemicTraumatic injuryLong-term opioid useAcute opioid withdrawalPersistent opioid useChronic opioid useOpioid use disorderAnalgesic regimensOpioid withdrawalAcute painHospital admissionOpioid dependencePatient populationUse disordersPatientsInadequate treatmentPainAverage riskMultimodal approachInjury
2018
Critical Care Pain Management in Patients Affected by the Opioid Epidemic: A Review
Karamchandani K, Carr Z, Bonavia A, Tung A. Critical Care Pain Management in Patients Affected by the Opioid Epidemic: A Review. Annals Of The American Thoracic Society 2018, 15: 1016-1023. DOI: 10.1513/annalsats.201801-028cme.Peer-Reviewed Original ResearchIntensive care unitOpioid dependenceOpioid epidemicLong-term opioid dependenceOpioid-related complicationsOpioid-tolerant patientsCritical care physiciansCritical care communitySufficient analgesiaICU carePain managementCare physiciansCare unitICU physiciansOpioid overdosesClinicians' attentionPatientsDirect careCare communityPhysiciansCareEpidemicDeleterious impactAnalgesiaOpioidsCritical Care Pain Management in Patients Affected by the Opioid Epidemic: A Review
Karamchandani K, Carr ZJ, Bonavia A, Tung A. Critical Care Pain Management in Patients Affected by the Opioid Epidemic: A Review. Annals Of The American Thoracic Society 2018, 15: 1016-1023. PMID: 29812953, DOI: 10.1513/annalsats.201801-028fr.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsIntensive care unitOpioid dependenceOpioid epidemicLong-term opioid dependenceOpioid-related complicationsOpioid-tolerant patientsCritical care physiciansCritical care communitySufficient analgesiaICU carePain managementCare physiciansCare unitICU physiciansOpioid overdosesClinicians' attentionPatientsDirect careCare communityPhysiciansCareEpidemicDeleterious impactAnalgesiaOpioidsOrgan Dysfunction After Surgery in Patients Treated With Individualized or Standard Blood Pressure Management
Karamchandani K, Carr ZJ, Bonavia A. Organ Dysfunction After Surgery in Patients Treated With Individualized or Standard Blood Pressure Management. JAMA 2018, 319: 719-719. PMID: 29466585, DOI: 10.1001/jama.2017.20935.Commentaries, Editorials and LettersIncreased whole blood FFA2/GPR43 receptor expression is associated with increased 30-day survival in patients with sepsis
Carr ZJ, Van De Louw A, Fehr G, Li JD, Kunselman A, Ruiz-Velasco V. Increased whole blood FFA2/GPR43 receptor expression is associated with increased 30-day survival in patients with sepsis. BMC Research Notes 2018, 11: 41. PMID: 29338778, PMCID: PMC5771199, DOI: 10.1186/s13104-018-3165-4.Peer-Reviewed Original ResearchConceptsRNA expressionIntensive care unit admissionBlood white cell countCare unit admissionOdds of mortalityDiagnosis of sepsisBody mass indexIntensive care unitWhite cell countGPR43 expressionUnit admissionOne-unit increaseCare unitMass indexSignificant morbidityQuantitative real-time PCRGPR43 receptorInflammatory responseImmunomodulatory pathwaysReceptor 43Receptor expressionReal-time PCRSepsisCell countPatients