2008
A PDZ‐Binding Motif Controls Basolateral Targeting of Syndecan‐1 Along the Biosynthetic Pathway in Polarized Epithelial Cells
Maday S, Anderson E, Chang HC, Shorter J, Satoh A, Sfakianos J, Fölsch H, Anderson JM, Walther Z, Mellman I. A PDZ‐Binding Motif Controls Basolateral Targeting of Syndecan‐1 Along the Biosynthetic Pathway in Polarized Epithelial Cells. Traffic 2008, 9: 1915-1924. PMID: 18764819, PMCID: PMC2820280, DOI: 10.1111/j.1600-0854.2008.00805.x.Peer-Reviewed Original ResearchConceptsPolarized epithelial cellsBiosynthetic pathwayPDZ domain-containing proteinsType II PDZDomain-containing proteinsPDZ-Binding MotifSyndecan-1Cell surface proteoglycansEpithelial cellsBasolateral targetingNormal epithelial morphologyBasolateral domainMotif leadPlasma membranePDZBasolateral localizationSurface proteoglycansBasolateral surfaceApical surfaceEpithelial morphologyMotifPotential rolePathwayCellsMislocalization
1988
Transcriptional regulation of the interferon-beta 2/B cell differentiation factor BSF-2/hepatocyte-stimulating factor gene in human fibroblasts by other cytokines.
Walther Z, May LT, Sehgal PB. Transcriptional regulation of the interferon-beta 2/B cell differentiation factor BSF-2/hepatocyte-stimulating factor gene in human fibroblasts by other cytokines. The Journal Of Immunology 1988, 140: 974-7. PMID: 3276786, DOI: 10.4049/jimmunol.140.3.974.Peer-Reviewed Original ResearchConceptsPlatelet-derived growth factorIL-1 alphaGene transcriptionIFN-beta 1IFN-beta 2 mRNAIL-1 alpha inductionIL-1 alpha-treated cellsAlpha-treated cellsHuman diploid fibroblastsTranscriptional regulationCycloheximide-treated cellsTranscription assaysEnhance transcriptionConfluent quiescent culturesTranscriptional levelFactor genesTranscriptional activityNuclear runFS-4 cellsTranscriptionGene 2Levels of mRNAHepatocyte-stimulating factorDiploid fibroblastsGenes