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Zenta Walther, MD, PhD

Associate Professor of Pathology
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Additional Titles

Director, Molecular Genetic Pathology Fellowship Program

About

Titles

Associate Professor of Pathology

Director, Molecular Genetic Pathology Fellowship Program

Biography

Dr. Walther is a physician-scientist with clinical expertise in gastrointestinal and liver pathology, the molecular diagnostics of surgical pathology specimens, and molecular oncology of solid tumors. Dr. Walther served as Clinical Director of the YNHH Tumor Profiling Laboratory for 12 years through the end of 2023, where she focused on molecular and genomic analyses of solid tumor specimens, to enable the identification of therapeutic targets within individual patients' cancers, and thus to promote precision medicine in oncology. She remains a key faculty member in the TPL and serves as Director of the Molecular Genetic Pathology Fellowship.

Appointments

Education & Training

Fellow
Yale University School of Medicine (2011)
Fellow
Yale University School of Medicine (2001)
Resident
Yale University School of Medicine (1997)
MD
Cornell University (1995)
PhD
Rockefeller University (1994)
BS
Yale University (1986)

Research

Research at a Glance

Yale Co-Authors

Frequent collaborators of Zenta Walther's published research.

Publications

2024

2023

2022

Clinical Trials

Current Trials

Clinical Care

Overview

Zenta Walther, MD, PhD, is the clinical director of the Yale New Haven Hospital Tumor Profiling Laboratory, and a pathologist who specializes in using molecular diagnostic techniques, especially next-generation sequencing, to analyze solid tumor tissues from patients. In particular, Dr. Walther looks for mutations within tumors that could be targeted with specific cancer drugs.

“I try to make personalized medicine possible for cancer patients,” Dr. Walther says. “And targeted therapies can often have fewer toxic side effects than conventional chemotherapy. I’m always eager to help patients find and enroll in available clinical trials.”

As an associate professor of pathology at Yale School of Medicine, Dr. Walther participates in translational research in addition to her clinical work. “By studying the genetic alterations in tumors before and after targeted therapy, we hope to gain new understanding that will lead to better treatment regimens and, ultimately, better outcomes for cancer patients.”

Clinical Specialties

Anatomic Pathology; Molecular & Genomic Pathology

Fact Sheets

Board Certifications

  • Molecular Genetic Pathology

    Certification Organization
    AB of Pathology
    Original Certification Date
    2011
  • Anatomic Pathology

    Certification Organization
    AB of Pathology
    Original Certification Date
    2001

Get In Touch

Contacts

Academic Office Number
Office Fax Number

Locations

  • Patient Care Locations

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Events

Dec 202413Friday
Jan 202510Friday
Feb 202514Friday
Mar 202514Friday