1996
The kinesin-homologous protein encoded by the Chlamydomonas FLA10 gene is associated with basal bodies and centrioles
Vashishtha M, Walther Z, Hall J. The kinesin-homologous protein encoded by the Chlamydomonas FLA10 gene is associated with basal bodies and centrioles. Journal Of Cell Science 1996, 109: 541-549. PMID: 8907700, DOI: 10.1242/jcs.109.3.541.Peer-Reviewed Original ResearchConceptsBasal bodiesMitotic spindleHomologous proteinsCell cycleUni linkage groupFamily of proteinsMotor domainCarboxy-terminal thirdTemperature-sensitive defectKinesin-related proteinEukaryotic evolutionFlagellar assemblyFlagellar developmentLinkage groupsFlagellar componentsSubcellular localizationPunctate structuresSea urchinsMolecular defectsProteinCentriolesAnalogous roleDirect roleMitosisGenes
1995
The uni chromosome of Chlamydomonas: histone genes and nucleosome structure
Walther Z, Hall J. The uni chromosome of Chlamydomonas: histone genes and nucleosome structure. Nucleic Acids Research 1995, 23: 3756-3763. PMID: 7479007, PMCID: PMC307276, DOI: 10.1093/nar/23.18.3756.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceCell DivisionChlamydomonas reinhardtiiChromatinChromosomesCloning, MolecularDNA, ProtozoanGene DosageGene Expression RegulationGenes, ProtozoanGenetic LinkageHistonesMolecular Sequence DataMultigene FamilyNucleosomesRestriction MappingRNA, MessengerRNA, ProtozoanSequence Analysis, DNAConceptsUni linkage groupHistone genesReplication-dependent histonesGene-specific probesNuclease protection experimentsAmino acid sequenceBasal body complexH4 genesHigher eukaryotesGenomic organizationHistone proteinsH3-H4Nucleosome structureLinkage groupsChlamydomonas reinhardtiiSouthern analysisAcid sequenceNorthern analysisProtection experimentsGenomic sequencingGenesBanding patternsNorthern blotS phaseChromosomes
1994
The Chlamydomonas FLA10 gene encodes a novel kinesin-homologous protein.
Walther Z, Vashishtha M, Hall JL. The Chlamydomonas FLA10 gene encodes a novel kinesin-homologous protein. Journal Of Cell Biology 1994, 126: 175-188. PMID: 8027176, PMCID: PMC2120091, DOI: 10.1083/jcb.126.1.175.Peer-Reviewed Original ResearchMeSH KeywordsAlgal ProteinsAmino Acid SequenceAnimalsBase SequenceCell CycleChlamydomonas reinhardtiiCloning, MolecularFlagellaGenes, ProtozoanKinesinsMicrotubule-Associated ProteinsMolecular Sequence DataMorphogenesisProtozoan ProteinsRestriction MappingRNA, MessengerSequence Analysis, DNASequence Homology, Amino AcidConceptsFlagellar assemblyAmino-terminal motor domainUni linkage groupCarboxy-terminal tailKinesin heavy chainTemperature-sensitive defectKinesin-related proteinCentral pair complexMotility mutantsMouse geneLinkage groupsCell divisionFla genesGene productsGenomic DNAFlagellar apparatusNovel roleWestern blot analysisGenesSynchronized culturesNucleotide sequencingAMP-PNPMolecular analysisAxonemeFLA10
1988
slit: An EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system
Rothberg J, Hartley D, Walther Z, Artavanis-Tsakonas S. slit: An EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system. Cell 1988, 55: 1047-1059. PMID: 3144436, DOI: 10.1016/0092-8674(88)90249-8.Peer-Reviewed Original ResearchConceptsEmbryonic central nervous systemD. melanogasterDeduced protein sequenceCentral nervous systemMidline glial cellsLongitudinal axon tractsEGF-like repeatsHigh-level expressionMolecular dataNervous systemProtein sequencesLoci resultsFamily of lociExtracellular localizationLevel expressionLociMelanogasterSitu hybridizationAxon tractsGenesEmbryosGlial cellsAntibody stainingPossible roleSequenceTranscriptional regulation of the interferon-beta 2/B cell differentiation factor BSF-2/hepatocyte-stimulating factor gene in human fibroblasts by other cytokines.
Walther Z, May LT, Sehgal PB. Transcriptional regulation of the interferon-beta 2/B cell differentiation factor BSF-2/hepatocyte-stimulating factor gene in human fibroblasts by other cytokines. The Journal Of Immunology 1988, 140: 974-7. PMID: 3276786, DOI: 10.4049/jimmunol.140.3.974.Peer-Reviewed Original ResearchConceptsPlatelet-derived growth factorIL-1 alphaGene transcriptionIFN-beta 1IFN-beta 2 mRNAIL-1 alpha inductionIL-1 alpha-treated cellsAlpha-treated cellsHuman diploid fibroblastsTranscriptional regulationCycloheximide-treated cellsTranscription assaysEnhance transcriptionConfluent quiescent culturesTranscriptional levelFactor genesTranscriptional activityNuclear runFS-4 cellsTranscriptionGene 2Levels of mRNAHepatocyte-stimulating factorDiploid fibroblastsGenes
1987
Rapid enhancement of beta 2-interferon/B-cell differentiation factor BSF-2 gene expression in human fibroblasts by diacylglycerols and the calcium ionophore A23187.
Sehgal PB, Walther Z, Tamm I. Rapid enhancement of beta 2-interferon/B-cell differentiation factor BSF-2 gene expression in human fibroblasts by diacylglycerols and the calcium ionophore A23187. Proceedings Of The National Academy Of Sciences Of The United States Of America 1987, 84: 3663-3667. PMID: 3108877, PMCID: PMC304935, DOI: 10.1073/pnas.84.11.3663.Peer-Reviewed Original ResearchConceptsGene expressionProtein kinase CProtein kinaseIFN-beta 2Cyclic nucleotide-dependent protein kinasesHuman fibroblastsFS-4 cellsKinase CCGMP-dependent protein kinaseRate of transcriptionProtein kinase C pathwayKinase C pathwayMRNA levelsFS-4 fibroblastsGene transcriptionVesicular stomatitis virusMin of additionCell growthGenesStomatitis virusC pathwayTranscriptionDiacylglycerolSynthetic diacylglycerolKinase