Featured Publications
Sleep-related predictors of cognition among adults with chronic insomnia and heart failure enrolled in a randomized controlled trial of cognitive behavioral therapy for insomnia.
Redeker N, Conley S, O'Connell M, Geer J, Yaggi H, Jeon S. Sleep-related predictors of cognition among adults with chronic insomnia and heart failure enrolled in a randomized controlled trial of cognitive behavioral therapy for insomnia. Journal Of Clinical Sleep Medicine 2023, 19: 1073-1081. PMID: 36740924, PMCID: PMC10235706, DOI: 10.5664/jcsm.10498.Peer-Reviewed Original ResearchConceptsChronic heart failureCognitive behavioral therapyHeart failureGroup time effectsRest-activity rhythmBehavioral therapyChronic insomniaCBT-I groupSelf-reported cognitive functionProportion of participantsTrial of CBTQuality of lifeSelf-management strategiesGroup-based CBTWalk distanceSleep apneaChronic illnessWrist actigraphyCognitive impairmentInsomniaTherapyCognitive functionMinute walkSelf-reported cognitive abilitiesBaseline cognitionRest-activity rhythms predict time to hospitalizations and emergency department visits among participants in a randomized control of adults with heart failure and insomnia
Jeon S, Conley S, Hollenbeak C, O'Connell M, Wang Z, Tocchi C, Redeker N. Rest-activity rhythms predict time to hospitalizations and emergency department visits among participants in a randomized control of adults with heart failure and insomnia. Sleep Medicine 2023, 108: 1-7. PMID: 37301192, PMCID: PMC10336725, DOI: 10.1016/j.sleep.2023.05.019.Peer-Reviewed Original ResearchConceptsRest-activity rhythmED visitsHeart failureEmergency departmentCircadian quotientEarly hospitalizationWrist actigraphyEarly ED visitsChronic heart failureLow ejection fractionFirst cardiac eventCox proportional hazardsEffects of insomniaCognitive behavioral therapyComposite eventsNYHA classHF patientsCardiac eventsCPAP useSevere painEjection fractionMale sexSevere insomniaHospitalizationInsomnia severityReal-time racial discrimination, affective states, salivary cortisol and alpha-amylase in Black adults
Nam S, Jeon S, Lee SJ, Ash G, Nelson LE, Granger DA. Real-time racial discrimination, affective states, salivary cortisol and alpha-amylase in Black adults. PLOS ONE 2022, 17: e0273081. PMID: 36103465, PMCID: PMC9473392, DOI: 10.1371/journal.pone.0273081.Peer-Reviewed Original ResearchConceptsAutonomic nervous systemEcological momentary assessmentDiurnal slopeCortisol levelsPhysiological stress responseBlack adultsMajor stress response systemsHealthy black adultsFlatter diurnal slopeDiurnal cortisol slopeNervous systemSalivary biomarkersHealth outcomesLarger sample sizeCortisol slopeSalivary cortisolConcurrent useBaseline surveyStress response systemStress responseCross-sectional dataCortisolSame dayFurther studiesAlpha-amylaseTrajectory of self-care in people with stable heart failure and insomnia after two self-care interventions
Conley S, Jeon S, Andrews L, Breazeale S, Hwang Y, O'Connell M, Linsky S, Redeker N. Trajectory of self-care in people with stable heart failure and insomnia after two self-care interventions. Patient Education And Counseling 2022, 105: 3487-3493. PMID: 36088189, DOI: 10.1016/j.pec.2022.09.001.Peer-Reviewed Original ResearchConceptsStable heart failureSelf-care interventionsHeart failureSevere baseline fatigueSelf-care supportSelf-care educationSelf-care groupEffects of CBTCognitive behavioral therapyGroup-based trajectory modelingBaseline fatigueEfficacious interventionsHealthcare providersSecondary analysisInsomniaBehavioral therapySelf-CareChi-squareDemographic characteristicsInterventionT-testFunctional performanceAdultsTrajectory modelingFailureSymptom Cluster Profiles Among Adults with Insomnia and Heart Failure
Conley S, Jeon S, Breazeale S, O’Connell M, Hollenbeak CS, Jacoby D, Linsky S, Yaggi HK, Redeker NS. Symptom Cluster Profiles Among Adults with Insomnia and Heart Failure. Behavioral Sleep Medicine 2022, 21: 150-161. PMID: 35388730, PMCID: PMC9537348, DOI: 10.1080/15402002.2022.2060226.Peer-Reviewed Original ResearchConceptsHigh symptom burdenHeart failureSymptom burdenSleep characteristicsLower symptom burdenChronic heart failureStable heart failureBody mass indexTreatment of insomniaStudy of insomniaHigh symptom profileCognitive behavioral therapyBeta blockersClinical characteristicsDaytime symptomsMass indexSevere insomniaSingle symptomInsomnia severitySymptom profilesInsomniaSymptom clustersBehavioral therapyHigher symptomsSymptomsCognitive behavioral therapy for insomnia has sustained effects on insomnia, fatigue, and function among people with chronic heart failure and insomnia: the HeartSleep Study
Redeker NS, Yaggi HK, Jacoby D, Hollenbeak CS, Breazeale S, Conley S, Hwang Y, Iennaco J, Linsky S, Nwanaji-Enwerem U, O’Connell M, Jeon S. Cognitive behavioral therapy for insomnia has sustained effects on insomnia, fatigue, and function among people with chronic heart failure and insomnia: the HeartSleep Study. Sleep 2021, 45: zsab252. PMID: 34657160, PMCID: PMC8754495, DOI: 10.1093/sleep/zsab252.Peer-Reviewed Original ResearchConceptsChronic heart failureSix-minute walk distanceStable heart failureHeart failureInsomnia severityWalk distanceSleep characteristicsSelf-reported sleep latencyGeneral linear mixed modelSelf-reported sleep characteristicsMonths of treatmentSelf-management educationSelf-management programSleep hygiene educationCognitive behavioral therapyEjection fractionPrimary outcomeDaytime symptomsExcessive daytimePhysical functionDaytime sleepinessSleep latencyMild insomniaSleep qualitySleep efficiencyRest-activity rhythms, daytime symptoms, and functional performance among people with heart failure
Jeon S, Conley S, Redeker NS. Rest-activity rhythms, daytime symptoms, and functional performance among people with heart failure. Chronobiology International 2020, 37: 1223-1234. PMID: 32588662, PMCID: PMC7529895, DOI: 10.1080/07420528.2020.1779280.Peer-Reviewed Original ResearchConceptsRest-activity rhythmStable heart failureHeart failureDaytime symptomsCircadian quotientPoorer New York Heart Association classNew York Heart Association classHF disease management programFunctional performanceBetter NYHA classChronic heart failureMinute walk testDisease management programsLess sleep fragmentationHF independentUnattended polysomnographyNYHA classGreater comorbidityAssociation classWalk testIntra-daily variabilityFunctional outcomePhysical functionPoor functionSleep fragmentationSleep Characteristics and Rest–Activity Rhythms Are Associated with Gastrointestinal Symptoms Among Adults with Inflammatory Bowel Disease
Conley S, Jeon S, Lehner V, Proctor DD, Redeker NS. Sleep Characteristics and Rest–Activity Rhythms Are Associated with Gastrointestinal Symptoms Among Adults with Inflammatory Bowel Disease. Digestive Diseases And Sciences 2020, 66: 181-189. PMID: 32193859, PMCID: PMC8162988, DOI: 10.1007/s10620-020-06213-6.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseRest-activity rhythmHeartburn/refluxDisease activityGI symptomsSleep characteristicsBowel diseaseGas/bloatingCross-sectional studySpecific sleep characteristicsRAR variablesGastrointestinal symptomsIntra-daily variabilityBackgroundSleep disturbancesSleep efficiencyAimsThe purposeSleep onsetSymptomsAdultsDiseaseRefluxPoor qualityAssociationRhythmRemissionLatent Transition Analysis of the Symptom Experience of Cancer Patients Undergoing Chemotherapy
Jeon S, Sikorskii A, Given BA, Given CW, Redeker NS. Latent Transition Analysis of the Symptom Experience of Cancer Patients Undergoing Chemotherapy. Nursing Research 2019, 68: 91-98. PMID: 30540701, PMCID: PMC6399048, DOI: 10.1097/nnr.0000000000000332.Peer-Reviewed Original ResearchConceptsSymptom experienceCancer patientsYoung adultsEmotional role functioningTreatment-related symptomsClass A patientsBetter physical functionAdult cancer patientsGeneral health perceptionRandomized clinical trialsClustering of symptomsPatients' symptom experiencesSymptom management interventionsLatent transition analysisNumber of symptomsQuality of lifeLess comorbidityA patientsSymptom managementPhysical functionClinical trialsHealth perceptionMultiple symptomsRole functioningPatients' membershipFour Approaches for Determining Composite Scores for the Measurement of Transition in Cancer Scale
Jeon S, Schulman-Green D, McCorkle R, Dixon JK. Four Approaches for Determining Composite Scores for the Measurement of Transition in Cancer Scale. Nursing Research 2019, 68: 57-64. PMID: 30247334, DOI: 10.1097/nnr.0000000000000318.Peer-Reviewed Original ResearchDiscrepancy between wrist‐actigraph and polysomnographic measures of sleep in patients with stable heart failure and a novel approach to evaluating discrepancy
Jeon S, Conley S, Redeker NS. Discrepancy between wrist‐actigraph and polysomnographic measures of sleep in patients with stable heart failure and a novel approach to evaluating discrepancy. Journal Of Sleep Research 2018, 28: e12717. PMID: 29943403, PMCID: PMC6309769, DOI: 10.1111/jsr.12717.Peer-Reviewed Original ResearchConceptsPoor sleep qualityTotal sleep timeHeart failurePolysomnographic measuresSleep qualitySleep measuresSleep timeHeart failure disease management programsMotor activityDaytime motor activityStable heart failureShorter total sleep timeCross-sectional studyPoor sleep efficiencyImportance of agingDisease management programsOlder patientsBland-Altman plotsSevere insomniaRisk factorsClinical dataIntra-class correlationSleep characteristicsSleep efficiencyWrist actigraphyPolysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea
Zinchuk AV, Jeon S, Koo BB, Yan X, Bravata DM, Qin L, Selim BJ, Strohl KP, Redeker NS, Concato J, Yaggi HK. Polysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea. Thorax 2017, 73: 472. PMID: 28935698, PMCID: PMC6693344, DOI: 10.1136/thoraxjnl-2017-210431.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedCardiovascular DiseasesCluster AnalysisCross-Sectional StudiesFemaleHumansIschemic Attack, TransientLongitudinal StudiesMaleMiddle AgedMortalityPhenotypePolysomnographyProportional Hazards ModelsRisk AssessmentSeverity of Illness IndexSleep Apnea, ObstructiveStrokeConceptsObstructive sleep apnoeaCardiovascular outcomesPolysomnographic featuresSleep apnoeaPolysomnographic dataIncident transient ischemic attackUS Veteran cohortTransient ischemic attackAcute coronary syndromeAdverse cardiovascular outcomesPeriodic limb movementsOSA severity classificationPolysomnographic phenotypeCoronary syndromeIschemic attackCardiovascular implicationsOSA phenotypesOSA evaluationPathophysiological domainsPoor sleepMild/Patient clustersVeteran cohortSurvival analysisCombined outcomeEffects of Cognitive Behavioral Therapy for Insomnia on Sleep-Related Cognitions Among Patients With Stable Heart Failure
Redeker NS, Jeon S, Andrews L, Cline J, Mohsenin V, Jacoby D. Effects of Cognitive Behavioral Therapy for Insomnia on Sleep-Related Cognitions Among Patients With Stable Heart Failure. Behavioral Sleep Medicine 2017, 17: 342-354. PMID: 28745520, PMCID: PMC5904007, DOI: 10.1080/15402002.2017.1357120.Peer-Reviewed Original ResearchConceptsEffects of CBTHF patientsSleep disturbance questionnaireCognitive behavioral therapySleep-related cognitionsStable New York Heart Association class IINew York Heart Association class IIInsomnia severityChronic heart failure patientsBehavioral therapyPittsburgh Sleep Quality IndexHigh symptom burdenStable heart failureHeart failure patientsSleep Quality IndexImproved sleep qualityInsomnia Severity IndexSelf-reported fatigueDysfunctional sleep-related cognitionsSymptom burdenFailure patientsHeart failureMixed-effects modelingSleep latencyPoor sleepWeight Gain and Metabolic Consequences of Risperidone in Young Children With Autism Spectrum Disorder
Scahill L, Jeon S, Boorin SJ, McDougle CJ, Aman MG, Dziura J, McCracken JT, Caprio S, Arnold LE, Nicol G, Deng Y, Challa SA, Vitiello B. Weight Gain and Metabolic Consequences of Risperidone in Young Children With Autism Spectrum Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2016, 55: 415-423. PMID: 27126856, PMCID: PMC4851735, DOI: 10.1016/j.jaac.2016.02.016.Peer-Reviewed Original ResearchConceptsWaist circumferenceWeight gainWeek 24Metabolic syndromeWeek 16Homeostatic model assessment-insulin resistanceMetabolic consequencesModel assessment-insulin resistanceBody mass index z-scoreAssessment-insulin resistanceLiver function testsTrial of risperidoneIndex z-scoreAutism spectrum disorderRapid weight gainRisperidone exposureBlood lipidsRisperidone monotherapyRisperidone treatmentFunction testsNormal weightInsulin resistanceAlanine aminotransferaseSpectrum disorderBlood samplesSleep Disturbance, Daytime Symptoms, and Functional Performance in Patients With Stable Heart Failure
Jeon S, Redeker NS. Sleep Disturbance, Daytime Symptoms, and Functional Performance in Patients With Stable Heart Failure. Nursing Research 2016, 65: 259-267. PMID: 27362512, PMCID: PMC4930009, DOI: 10.1097/nnr.0000000000000169.Peer-Reviewed Original ResearchConceptsSelf-reported functional performanceStable heart failureDaytime symptomsHeart failureSleep disturbancesNew York Heart Association class ISix-minute walk testFunctional performanceRespiratory disturbance indexPoorer functional performanceHF patientsSymptom burdenWalk testRespiratory indexObservational studySleep qualityInsomnia symptomsAmbulatory polysomnographyPatientsSecondary analysisSymptomsClass IDisturbance indexExploratory regression analysisRegression analysisDetecting a clinically meaningful change in tic severity in Tourette syndrome: A comparison of three methods
Jeon S, Walkup JT, Woods DW, Peterson A, Piacentini J, Wilhelm S, Katsovich L, McGuire JF, Dziura J, Scahill L. Detecting a clinically meaningful change in tic severity in Tourette syndrome: A comparison of three methods. Contemporary Clinical Trials 2013, 36: 414-420. PMID: 24001701, PMCID: PMC3999642, DOI: 10.1016/j.cct.2013.08.012.Peer-Reviewed Original ResearchConceptsOdds ratioTourette syndromeYGTSS total tic scoreChronic tic disorderPositive treatment responsePositive responseTic scoreTic disordersTreatment responseTic severityTreatment assignmentBehavioral treatmentSignal detection analysisBehavioral interventionsSyndromeCGICategorical measuresTrialsMeaningful changeSeverityPercent reductionOptimal sensitivityDimensional measuresResponse
2024
Measuring intersectional HIV, sexual diversity, and gender non-conformity stigma among healthcare workers in Ghana: scale validation and correlates of stigma
Oga E, Stockton M, Abu-Ba’are G, Vormawor R, Mankattah E, Endres-Dighe S, Richmond R, Jeon S, Logie C, Baning E, Saalim K, Torpey K, Nelson L, Nyblade L. Measuring intersectional HIV, sexual diversity, and gender non-conformity stigma among healthcare workers in Ghana: scale validation and correlates of stigma. BMC Health Services Research 2024, 24: 647. PMID: 38773589, PMCID: PMC11110277, DOI: 10.1186/s12913-024-11098-6.Peer-Reviewed Original ResearchConceptsIntersectional stigmaIntersectional identitiesHealthcare facility staffHealthcare facilitiesGender non-conformity stigmaStigmatizing beliefsGender non-conformingSame-sex relationshipsReduce intersectional stigmaSame-gender sexFactors associated with stigmaAssociated with less stigmaMethodsWe analyzed baseline dataStigma reduction interventionsGreater comfortCorrelates of stigmaMulti-level interventionsInfection control trainingSexual diversitySexual normsAssociated with greater comfortGreater religiosityHIV testingResultsFactor analysisExploratory factor analysisIL-1 receptor 1 signaling shapes the development of viral antigen-specific CD4+ T cell responses following COVID-19 mRNA vaccination
Park H, Shin M, Shin J, Kim H, Kang B, Par-Young J, Unlu S, Afinogenova Y, Catanzaro J, Young J, Kim M, Lee S, Jeon S, You S, Racke M, Bucala R, Kang I. IL-1 receptor 1 signaling shapes the development of viral antigen-specific CD4+ T cell responses following COVID-19 mRNA vaccination. EBioMedicine 2024, 103: 105114. PMID: 38640835, PMCID: PMC11041015, DOI: 10.1016/j.ebiom.2024.105114.Peer-Reviewed Original ResearchConceptsCD4<sup>+</sup> T cellsCOVID-19 mRNA vaccinesAntigen-specific CD4<sup>+</sup> T cell responsesT cell responsesPrimary antibody deficiencyCD4<sup>+</sup> T cell responsesT cellsIL-1R1MRNA vaccinesIL-1IgG antibodiesAntigen-specific CD4<sup>+</sup> T cellsCD4+ T cell responsesLevels of IL-1R1Human CD4<sup>+</sup> T cellsIL-1 receptor 1Healthy individualsDose of COVID-19 mRNA vaccineAntigen-specific CD4IL-1R1 expressionT cell immunityRepetitive antigenic stimulationCytokines interleukin (IL)-1Immune response to virusesExpression of IL-1R1Study Recruitment, Retention, and Adherence Among Chinese American Immigrants During the COVID-19 Pandemic
Huang S, Nam S, Ash G, Wu B, Melkus G, Jeon S, McMahon E, Dickson V, Whittemore R. Study Recruitment, Retention, and Adherence Among Chinese American Immigrants During the COVID-19 Pandemic. Nursing Research 2024, 73: 328-336. PMID: 38905624, DOI: 10.1097/nnr.0000000000000731.Peer-Reviewed Original ResearchConceptsChinese American immigrantsRecruitment strategiesRetention strategiesSnowball samplingOnline surveyMultiple recruitment strategiesPhysical activity studiesForeign-born Chinese womenCOVID-19 pandemicAmerican immigrantsGestational diabetesDiverse socioeconomic groupsStudy websiteReport adherenceEmail remindersGeographically diverse sampleHealth researchText remindersAdherence strategiesCommunity outreachStudy recruitmentDiabetes diagnosisIndex pregnancyStudy webpageChinese womenAssociation between adverse childhood experiences and self-reported health-risk behaviors among cancer survivors: A population-based study
Sarkar S, Jackson B, Manzo L, Jeon S, Poghosyan H. Association between adverse childhood experiences and self-reported health-risk behaviors among cancer survivors: A population-based study. PLOS ONE 2024, 19: e0299918. PMID: 38512934, PMCID: PMC10956880, DOI: 10.1371/journal.pone.0299918.Peer-Reviewed Original ResearchConceptsHealth risk behaviorsSelf-reported health risk behaviorsAdverse childhood experiencesHistory of adverse childhood experiencesOdds of reportingCancer survivorsE-cigarette useIncreased odds of reportingReport adverse childhood experiencesPrevalence of adverse childhood experiencesSelf-reportAlcohol drinkingHigher odds of reportingAdult cancer survivorsE-cigarettesSurvivor self-reportPrevent health risk behaviorsAdverse childhood experience historyChildhood experiencesAssociated with health risk behaviorsCigarette smokingHistory of cancerPopulation-based studyPrimary independent variableMultivariate logistic regression