Sangchoon Jeon, PhD
Cards
About
Titles
Senior Research Scientist
Biography
Dr. Sangchoon Jeon is a biostatistician who was trained in statistics (BS, MS) and epidemiology (PhD). His dissertation was evaluating cancer-related symptom changes using alternative survival analysis approaches with considering important statistical assumptions. Primarily, Dr. Jeon has actively participated in evaluating cognitive behavioral interventions for adolescents with diabetes, sleep disturbance in heart failure patients, symptom management in cancer patients, and an exercise intervention for breast cancer survivors. Jeon is currently participating as biostatistician on the method core for the Yale Center for Sleep Disturbance in Acute and Chronic Illness.
He is currently interested in parametric and non-parametric methods for analyzing circadian rhythmicity of continuous motor activity, and prediction of symptoms and mortality in heart failure patients. Notably, his recent publications in evaluating actigraph data in heart failure patients show the discrepancy between actigraphy and polysomnography in sleep disturbance and the associations between RAR metrics, daytime symptoms, and functional performance.
Education & Training
- PhD
- Michigan State University, Epidemiology (2009)
- MS
- Michigan State University, Epidemiology (2006)
- MS
- Michigan State University, Statistics (2003)
- BA
- Yeungnam University, Statistics (1997)
Research
Publications
Daytime symptom trajectories among adults with stable heart failure and insomnia: evidence from a randomised controlled trial of cognitive behavioural therapy for insomnia
Conley S, Jeon S, Wang Z, Tocchi C, Linsky S, O'Connell M, Redeker N. Daytime symptom trajectories among adults with stable heart failure and insomnia: evidence from a randomised controlled trial of cognitive behavioural therapy for insomnia. Journal Of Sleep Research 2023, 33: e14058. PMID: 37933085, DOI: 10.1111/jsr.14058.Peer-Reviewed Original ResearchStable heart failureHeart failureSelf-management groupSymptom trajectoriesCognitive behavioral therapyBehavioral therapyHigher body mass indexGroup-based trajectory modellingHigh symptom burdenHealth-related qualityBody mass indexTrial of CBTFunctional performanceSelf-management interventionsBaseline characteristicsSymptom burdenMass indexBaseline fatigueGroup AHigher oddsSleep characteristicsInsomnia severityGroup DPhysical symptomsInsomniaSleep-related predictors of cognition among adults with chronic insomnia and heart failure enrolled in a randomized controlled trial of cognitive behavioral therapy for insomnia.
Redeker N, Conley S, O'Connell M, Geer J, Yaggi H, Jeon S. Sleep-related predictors of cognition among adults with chronic insomnia and heart failure enrolled in a randomized controlled trial of cognitive behavioral therapy for insomnia. Journal Of Clinical Sleep Medicine 2023, 19: 1073-1081. PMID: 36740924, PMCID: PMC10235706, DOI: 10.5664/jcsm.10498.Peer-Reviewed Original ResearchConceptsChronic heart failureCognitive behavioral therapyHeart failureGroup time effectsRest-activity rhythmBehavioral therapyChronic insomniaCBT-I groupSelf-reported cognitive functionProportion of participantsTrial of CBTQuality of lifeSelf-management strategiesGroup-based CBTWalk distanceSleep apneaChronic illnessWrist actigraphyCognitive impairmentInsomniaTherapyCognitive functionMinute walkSelf-reported cognitive abilitiesBaseline cognitionRest-activity rhythms predict time to hospitalizations and emergency department visits among participants in a randomized control of adults with heart failure and insomnia
Jeon S, Conley S, Hollenbeak C, O'Connell M, Wang Z, Tocchi C, Redeker N. Rest-activity rhythms predict time to hospitalizations and emergency department visits among participants in a randomized control of adults with heart failure and insomnia. Sleep Medicine 2023, 108: 1-7. PMID: 37301192, PMCID: PMC10336725, DOI: 10.1016/j.sleep.2023.05.019.Peer-Reviewed Original ResearchConceptsRest-activity rhythmED visitsHeart failureEmergency departmentCircadian quotientEarly hospitalizationWrist actigraphyEarly ED visitsChronic heart failureLow ejection fractionFirst cardiac eventCox proportional hazardsEffects of insomniaCognitive behavioral therapyComposite eventsNYHA classHF patientsCardiac eventsCPAP useSevere painEjection fractionMale sexSevere insomniaHospitalizationInsomnia severityReal-time racial discrimination, affective states, salivary cortisol and alpha-amylase in Black adults
Nam S, Jeon S, Lee SJ, Ash G, Nelson LE, Granger DA. Real-time racial discrimination, affective states, salivary cortisol and alpha-amylase in Black adults. PLOS ONE 2022, 17: e0273081. PMID: 36103465, PMCID: PMC9473392, DOI: 10.1371/journal.pone.0273081.Peer-Reviewed Original ResearchConceptsAutonomic nervous systemEcological momentary assessmentDiurnal slopeCortisol levelsPhysiological stress responseBlack adultsMajor stress response systemsHealthy black adultsFlatter diurnal slopeDiurnal cortisol slopeNervous systemSalivary biomarkersHealth outcomesLarger sample sizeCortisol slopeSalivary cortisolConcurrent useBaseline surveyStress response systemStress responseCross-sectional dataCortisolSame dayFurther studiesAlpha-amylaseTrajectory of self-care in people with stable heart failure and insomnia after two self-care interventions
Conley S, Jeon S, Andrews L, Breazeale S, Hwang Y, O'Connell M, Linsky S, Redeker N. Trajectory of self-care in people with stable heart failure and insomnia after two self-care interventions. Patient Education And Counseling 2022, 105: 3487-3493. PMID: 36088189, DOI: 10.1016/j.pec.2022.09.001.Peer-Reviewed Original ResearchConceptsStable heart failureSelf-care interventionsHeart failureSevere baseline fatigueSelf-care supportSelf-care educationSelf-care groupEffects of CBTCognitive behavioral therapyGroup-based trajectory modelingBaseline fatigueEfficacious interventionsHealthcare providersSecondary analysisInsomniaBehavioral therapySelf-CareChi-squareDemographic characteristicsInterventionT-testFunctional performanceAdultsTrajectory modelingFailureSymptom Cluster Profiles Among Adults with Insomnia and Heart Failure
Conley S, Jeon S, Breazeale S, O’Connell M, Hollenbeak CS, Jacoby D, Linsky S, Yaggi HK, Redeker NS. Symptom Cluster Profiles Among Adults with Insomnia and Heart Failure. Behavioral Sleep Medicine 2022, 21: 150-161. PMID: 35388730, PMCID: PMC9537348, DOI: 10.1080/15402002.2022.2060226.Peer-Reviewed Original ResearchConceptsHigh symptom burdenHeart failureSymptom burdenSleep characteristicsLower symptom burdenChronic heart failureStable heart failureBody mass indexTreatment of insomniaStudy of insomniaHigh symptom profileCognitive behavioral therapyBeta blockersClinical characteristicsDaytime symptomsMass indexSevere insomniaSingle symptomInsomnia severitySymptom profilesInsomniaSymptom clustersBehavioral therapyHigher symptomsSymptomsCognitive behavioral therapy for insomnia has sustained effects on insomnia, fatigue, and function among people with chronic heart failure and insomnia: the HeartSleep Study
Redeker NS, Yaggi HK, Jacoby D, Hollenbeak CS, Breazeale S, Conley S, Hwang Y, Iennaco J, Linsky S, Nwanaji-Enwerem U, O’Connell M, Jeon S. Cognitive behavioral therapy for insomnia has sustained effects on insomnia, fatigue, and function among people with chronic heart failure and insomnia: the HeartSleep Study. Sleep 2021, 45: zsab252. PMID: 34657160, PMCID: PMC8754495, DOI: 10.1093/sleep/zsab252.Peer-Reviewed Original ResearchConceptsChronic heart failureSix-minute walk distanceStable heart failureHeart failureInsomnia severityWalk distanceSleep characteristicsSelf-reported sleep latencyGeneral linear mixed modelSelf-reported sleep characteristicsMonths of treatmentSelf-management educationSelf-management programSleep hygiene educationCognitive behavioral therapyEjection fractionPrimary outcomeDaytime symptomsExcessive daytimePhysical functionDaytime sleepinessSleep latencyMild insomniaSleep qualitySleep efficiencyRacial Discrimination, Sedentary Time, and Physical Activity in African Americans: Quantitative Study Combining Ecological Momentary Assessment and Accelerometers
Nam S, Jeon S, Ash G, Whittemore R, Vlahov D. Racial Discrimination, Sedentary Time, and Physical Activity in African Americans: Quantitative Study Combining Ecological Momentary Assessment and Accelerometers. JMIR Formative Research 2021, 5: e25687. PMID: 34096870, PMCID: PMC8218214, DOI: 10.2196/25687.Peer-Reviewed Original ResearchINTERNATIONAL REGISTERED REPORT IDENTIFIERPhysical activitySedentary timeEcological momentary assessmentDaily racial discriminationHealth behaviorsAfrican AmericansPA outcomesCross-sectional studyHealthy African AmericansPerson associationsCase-crossover designDaily ecological momentary assessmentsTotal energy expenditureSocial stressDay-level associationsLifetime racial discriminationMomentary assessmentDepressive symptomsPrecision health approachYounger ageHealth disparitiesPA levelsHealth approachConcurrent useRest-activity rhythms, daytime symptoms, and functional performance among people with heart failure
Jeon S, Conley S, Redeker NS. Rest-activity rhythms, daytime symptoms, and functional performance among people with heart failure. Chronobiology International 2020, 37: 1223-1234. PMID: 32588662, PMCID: PMC7529895, DOI: 10.1080/07420528.2020.1779280.Peer-Reviewed Original ResearchConceptsRest-activity rhythmStable heart failureHeart failureDaytime symptomsCircadian quotientPoorer New York Heart Association classNew York Heart Association classHF disease management programFunctional performanceBetter NYHA classChronic heart failureMinute walk testDisease management programsLess sleep fragmentationHF independentUnattended polysomnographyNYHA classGreater comorbidityAssociation classWalk testIntra-daily variabilityFunctional outcomePhysical functionPoor functionSleep fragmentationSleep Characteristics and Rest–Activity Rhythms Are Associated with Gastrointestinal Symptoms Among Adults with Inflammatory Bowel Disease
Conley S, Jeon S, Lehner V, Proctor DD, Redeker NS. Sleep Characteristics and Rest–Activity Rhythms Are Associated with Gastrointestinal Symptoms Among Adults with Inflammatory Bowel Disease. Digestive Diseases And Sciences 2020, 66: 181-189. PMID: 32193859, PMCID: PMC8162988, DOI: 10.1007/s10620-020-06213-6.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseRest-activity rhythmHeartburn/refluxDisease activityGI symptomsSleep characteristicsBowel diseaseGas/bloatingCross-sectional studySpecific sleep characteristicsRAR variablesGastrointestinal symptomsIntra-daily variabilityBackgroundSleep disturbancesSleep efficiencyAimsThe purposeSleep onsetSymptomsAdultsDiseaseRefluxPoor qualityAssociationRhythmRemission