Detecting a clinically meaningful change in tic severity in Tourette syndrome: A comparison of three methods
Jeon S, Walkup JT, Woods DW, Peterson A, Piacentini J, Wilhelm S, Katsovich L, McGuire JF, Dziura J, Scahill L. Detecting a clinically meaningful change in tic severity in Tourette syndrome: A comparison of three methods. Contemporary Clinical Trials 2013, 36: 414-420. PMID: 24001701, PMCID: PMC3999642, DOI: 10.1016/j.cct.2013.08.012.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBehavior TherapyChildHumansMaleMiddle AgedSeverity of Illness IndexTicsTourette SyndromeTreatment OutcomeYoung AdultConceptsOdds ratioTourette syndromeYGTSS total tic scoreChronic tic disorderPositive treatment responsePositive responseTic scoreTic disordersTreatment responseTic severityTreatment assignmentBehavioral treatmentSignal detection analysisBehavioral interventionsSyndromeCGICategorical measuresTrialsMeaningful changeSeverityPercent reductionOptimal sensitivityDimensional measuresResponse