2009
The Utility of Screening in the Design of Trials for Symptom Management in Cancer
Jeon S, Given CW, Sikorskii A, Given B. The Utility of Screening in the Design of Trials for Symptom Management in Cancer. Journal Of Pain And Symptom Management 2009, 38: 606-614. PMID: 19699052, PMCID: PMC2761530, DOI: 10.1016/j.jpainsymman.2009.02.233.Peer-Reviewed Original ResearchConceptsSymptom managementIntervention contactsSeverity scoreClinical trialsCancer symptom management trialsLikelihood ratioUtility of screeningSeverity of symptomsDesign of trialsSymptom management trialsPost-test probabilityReceipt of interventionTrial entryCancer patientsPatientsTrial designSymptomsDiscriminative accuracyRating ScaleTrialsSeverityCharacteristic curveManagement trialsCancerInterventionDifferential Symptom Reporting by Mode of Administration of the Assessment
Sikorskii A, Given CW, Given B, Jeon S, You M. Differential Symptom Reporting by Mode of Administration of the Assessment. Medical Care 2009, 47: 866-874. PMID: 19584761, PMCID: PMC2722377, DOI: 10.1097/mlr.0b013e3181a31d00.Peer-Reviewed Original ResearchConceptsNurse armSymptom managementMode of administrationIntervention contactsSymptom reportingTelephone interviewsPatient-reported outcome dataCancer-related symptomsSymptom management strategiesSymptom management interventionsHigher severityPoor appetitePatient reportingCancer patientsSymptom assessmentClinical trialsSymptom monitoringOutcome dataPatientsClinical practiceSolid tumorsVoice response systemOlder groupSymptomsIntake interviewResponse analysis for multiple symptoms revealed differences between arms of a symptom management trial
Sikorskii A, Given CW, You M, Jeon S, Given BA. Response analysis for multiple symptoms revealed differences between arms of a symptom management trial. Journal Of Clinical Epidemiology 2009, 62: 716-724. PMID: 19124223, PMCID: PMC2743381, DOI: 10.1016/j.jclinepi.2008.09.007.Peer-Reviewed Original ResearchConceptsSymptom management trialsIntervention contactsMultiple symptomsCancer-related symptomsProportional hazards modelManagement trialsScore of severityCancer painClinical improvementPoor appetiteSymptom managementCognitive-behavioral interventionsDisease characteristicsCancer patientsHazards modelPatientsSymptomsStudy designTrialsSeverityGood responseMarginal proportional hazards modelInterventionArmResponse
2007
Symptom Management for Cancer Patients: A Trial Comparing Two Multimodal Interventions
Sikorskii A, Given CW, Given B, Jeon S, Decker V, Decker D, Champion V, McCorkle R. Symptom Management for Cancer Patients: A Trial Comparing Two Multimodal Interventions. Journal Of Pain And Symptom Management 2007, 34: 253-264. PMID: 17618080, PMCID: PMC2043403, DOI: 10.1016/j.jpainsymman.2006.11.018.Peer-Reviewed Original ResearchConceptsLung cancer patientsCancer patientsSymptom managementIntervention contactsSymptom severityNon-lung cancer patientsSeverity of symptomsGreater symptom severitySignificant reductionConventional careSevere symptomsMultimodal interventionPatientsSymptom patternsSolid tumorsEight-weekPrior trialsPostintervention observationSeveritySymptomsInteractive interventionChemotherapyInterventionLongitudinal analysisBaseline