Randy Luciano, MD, PhD
Associate Professor of MedicineCards
About
Research
Publications
2026
Percutaneous Native Kidney Biopsy Complications in Diabetic Patients in the TRIDENT Cohort.
Mohandes S, Fakhreddine M, Sheng H, Al Dulaimee M, Mottl A, Scialla J, Almaani S, Luciano R, Isakova T, Bansal S, Argyropoulos C, Avasare R, Singh M, Campbell K, Townsend R, Coppock G, Palmer M, Susztak K. Percutaneous Native Kidney Biopsy Complications in Diabetic Patients in the TRIDENT Cohort. Clinical Journal Of The American Society Of Nephrology 2026 PMID: 42295857, DOI: 10.2215/cjn.0000001083.Peer-Reviewed Original Research
2025
Association of Kidney Biopsy Needle Gauge with Postprocedure Complications and Biopsy Adequacy
Staunton M, Garg K, Sadarangani S, Makhijani A, Shelton K, Koval E, Liang C, Shaw M, Kent C, Wilson F, Parikh C, Perazella M, Turner J, Luciano R, Moledina DG. Association of Kidney Biopsy Needle Gauge with Postprocedure Complications and Biopsy Adequacy. Kidney360 2025, 6: 1682-1688. PMID: 40402808, PMCID: PMC12778012, DOI: 10.34067/kid.0000000835.Peer-Reviewed Original Research
2024
The Case | An active injection drug user with a skin rash and kidney failure
Aron A, Luciano R. The Case | An active injection drug user with a skin rash and kidney failure. Kidney International 2024, 105: 1327-1328. DOI: 10.1016/j.kint.2024.03.009.Peer-Reviewed Original ResearchIdentification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis
Moledina DG, Obeid W, Smith R, Rosales I, Sise M, Moeckel G, Kashgarian M, Kuperman M, Campbell K, Lefferts S, Meliambro K, Bitzer M, Perazella M, Luciano R, Pober J, Cantley L, Colvin R, Wilson F, Parikh C. Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis. Journal Of Clinical Investigation 2024, 134: e180583. PMID: 38488004, PMCID: PMC10940080, DOI: 10.1172/jci180583.Commentaries, Editorials and LettersRationale and Design of a Phase 2, Double-blind, Placebo-Controlled, Randomized Trial Evaluating AMP Kinase-Activation by Metformin in Focal Segmental Glomerulosclerosis
Barsotti G, Luciano R, Kumar A, Meliambro K, Kakade V, Tokita J, Naik A, Fu J, Peck E, Pell J, Reghuvaran A, Tanvir E, Patel P, Zhang W, Li F, Moeckel G, Perincheri S, Cantley L, Moledina DG, Wilson F, He J, Menon M. Rationale and Design of a Phase 2, Double-blind, Placebo-Controlled, Randomized Trial Evaluating AMP Kinase-Activation by Metformin in Focal Segmental Glomerulosclerosis. Kidney International Reports 2024, 9: 1354-1368. PMID: 38707807, PMCID: PMC11068976, DOI: 10.1016/j.ekir.2024.02.006.Peer-Reviewed Original Research
2023
Guillain-Barre Syndrome Presenting Alongside Lupus Nephritis: Case and Management
Mehta P, Luciano R, Aklilu A, Malvar G. Guillain-Barre Syndrome Presenting Alongside Lupus Nephritis: Case and Management. Journal Of The American Society Of Nephrology 2023, 34: 277-277. DOI: 10.1681/asn.20233411s1277a.Peer-Reviewed Original ResearchDiffuse Alveolar Hemorrhage Presenting in IgA Nephropathy
Jobson C, Luciano R, Shirali A, Malvar G. Diffuse Alveolar Hemorrhage Presenting in IgA Nephropathy. Journal Of The American Society Of Nephrology 2023, 34: 1119-1119. DOI: 10.1681/asn.20233411s11119a.Peer-Reviewed Original ResearchIdentification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis
Moledina DG, Obeid W, Smith R, Rosales I, Sise M, Moeckel G, Kashgarian M, Kuperman M, Campbell K, Lefferts S, Meliambro K, Bitzer M, Perazella M, Luciano R, Pober J, Cantley L, Colvin R, Wilson F, Parikh C. Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis. Journal Of Clinical Investigation 2023, 133: e168950. PMID: 37395276, PMCID: PMC10313360, DOI: 10.1172/jci168950.Peer-Reviewed Original Research
2022
Safety and Adequacy of Kidney Biopsy Procedure in Patients with Obesity
Qian L, Menez S, Hu D, Weinstein J, Melchinger H, Thiessen-Philbrook H, Luciano R, Turner J, Perazella M, Villalobos C, Shaw M, Wilson F, Parikh C, Moledina DG. Safety and Adequacy of Kidney Biopsy Procedure in Patients with Obesity. Kidney360 2022, 4: 98-101. PMID: 36700910, PMCID: PMC10101611, DOI: 10.34067/kid.0006602022.Peer-Reviewed Original ResearchAA Amyloidosis Presenting With Renal Amyloidoma
Gunasekaran D, Luciano R. AA Amyloidosis Presenting With Renal Amyloidoma. Journal Of The American Society Of Nephrology 2022, 33: 167-168. DOI: 10.1681/asn.20223311s1167e.Peer-Reviewed Original Research
Clinical Trials
Current Trials
Treating Kidney Disease in Patients with APOL1
IRB ID2000030942RoleSub InvestigatorPrimary Completion Date05/31/2026Recruiting ParticipantsGenderBothAge18 years - 60 years
Academic Achievements & Community Involvement
Clinical Care
Overview
Randy Luciano, MD, PhD, has expertise in treating patients with glomerular disease (a kind of kidney disease that affects the filtering aspect of the kidney) and kidney-related vasculitis. Additionally, Dr. Luciano treats patients with, but not limited to, minimal change disease, membranous nephropathy, FSGS, renal amyloidosis, Lupus nephritis, IgA nephropathy, and ANCA mediated vasculitis. He is directly involved in the diagnosis (through biopsy) and treatment of patients with glomerular disease. In addition, he coordinates several clinical trials to help further progress the treatment options for these diseases.
Clinical Specialties
Nephrology; Rheumatology
Fact Sheets
Polycystic Kidney Disease (PKD)
Learn More on Yale MedicineGlomerulonephritis
Learn More on Yale MedicineDiagnosing Lupus Nephritis
Learn More on Yale MedicineAcute Kidney Injury (AKI)
Learn More on Yale Medicine
Yale Medicine News
News
News
- August 26, 2025
Yale Department of Internal Medicine Faculty Promotions and Appointments (August 2025)
- July 25, 2025Source: Yale Medicine
Two Simple Tests That Can Help Detect Kidney Conditions Early
- April 24, 2024Source: Yale Medicine
Why Is Chronic Kidney Disease (CKD) on the Rise? 6 Things to Know
- September 14, 2023
Smilow Shares: AL Amyloidosis
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