Mark Perazella, MD
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Appointments
Nephrology
Primary
Titles
Director, Acute Dialysis Unit; Medical Director, Yale Physician Associate Program; Medical Director, Yale PA Online Program
Contact Info
Appointments
Nephrology
Primary
Titles
Director, Acute Dialysis Unit; Medical Director, Yale Physician Associate Program; Medical Director, Yale PA Online Program
Contact Info
Appointments
Nephrology
Primary
Titles
Director, Acute Dialysis Unit; Medical Director, Yale Physician Associate Program; Medical Director, Yale PA Online Program
Contact Info
About
Titles
Professor Emeritus of Medicine
Director, Acute Dialysis Unit; Medical Director, Yale Physician Associate Program; Medical Director, Yale PA Online ProgramAppointments
Nephrology
EmeritusPrimary
Other Departments & Organizations
Education & Training
- MD
- New York Medical College (1988)
- Resident
- St. Mary's Hospital
- Fellow
- Yale University School of Medicine
Research
Overview
Medical Subject Headings (MeSH)
Dialysis; Drug-Related Side Effects and Adverse Reactions; Hemodialysis Units, Hospital; HIV; Hypotension; Kidney Diseases; Kidney Failure, Chronic; Nephrogenic Fibrosing Dermopathy; Nephrology
ORCID
0000-0002-6994-2659
Research at a Glance
Yale Co-Authors
Frequent collaborators of Mark Perazella's published research.
Publications Timeline
A big-picture view of Mark Perazella's research output by year.
Research Interests
Research topics Mark Perazella is interested in exploring.
Dennis G Moledina, MD, PhD, FASN
F. Perry Wilson, MD, MSCE
Megan Leila Baker, MD
Ali Abu-Alfa, MD, FASN, FAHA
Lloyd G. Cantley, MD
Michael Kashgarian, MD, FASN
158Publications
5,111Citations
Kidney Failure, Chronic
Kidney Diseases
Drug-Related Side Effects and Adverse Reactions
Hypotension
Nephrology
Publications
2024
Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis
Moledina D, Obeid W, Smith R, Rosales I, Sise M, Moeckel G, Kashgarian M, Kuperman M, Campbell K, Lefferts S, Meliambro K, Bitzer M, Perazella M, Luciano R, Pober J, Cantley L, Colvin R, Wilson F, Parikh C. Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis. Journal Of Clinical Investigation 2024, 134: e180583. PMID: 38488004, PMCID: PMC10940080, DOI: 10.1172/jci180583.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsToxic Nephropathies of the Tubulointerstitium: Core Curriculum 2024
Krishnan N, Moledina D, Perazella M. Toxic Nephropathies of the Tubulointerstitium: Core Curriculum 2024. American Journal Of Kidney Diseases 2024, 83: 659-676. PMID: 38243994, DOI: 10.1053/j.ajkd.2023.09.017.Peer-Reviewed Original ResearchCitationsAltmetricConceptsRenal injurySeverity of renal injuryToxic nephropathyTubulointerstitial renal injuryIrreversible renal injuryToxin-induced renal injuryImmune response genesNephrotoxic riskClinical presentationTubulointerstitial injuryRenal functionClinical manifestationsPatient characteristicsTubular secretionGlomerular filtrationComorbid conditionsMetabolic handlingDrug metabolismExcretory pathwayInjuryTransport defectAdverse effectsTubulointerstitiumNephropathyExogenous toxins
2023
Hiding in Plain Sight: Catastrophic Diethylene Glycol Poisoning in Children
Perazella M. Hiding in Plain Sight: Catastrophic Diethylene Glycol Poisoning in Children. Kidney360 2023, 4: 1534-1535. PMID: 37831818, PMCID: PMC10695641, DOI: 10.34067/kid.0000000000000269.Peer-Reviewed Original ResearchMeSH KeywordsA Patient with an Unusual Cause of AKI and Scrotal Swelling
Gomez D, Perazella M. A Patient with an Unusual Cause of AKI and Scrotal Swelling. Kidney360 2023, 4: 1188-1189. PMID: 37651667, PMCID: PMC10484347, DOI: 10.34067/kid.0000000000000125.Peer-Reviewed Original ResearchAltmetricIdentification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis
Moledina D, Obeid W, Smith R, Rosales I, Sise M, Moeckel G, Kashgarian M, Kuperman M, Campbell K, Lefferts S, Meliambro K, Bitzer M, Perazella M, Luciano R, Pober J, Cantley L, Colvin R, Wilson F, Parikh C. Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis. Journal Of Clinical Investigation 2023, 133: e168950. PMID: 37395276, PMCID: PMC10313360, DOI: 10.1172/jci168950.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsUrinary CXCL9External validation cohortValidation cohortControl groupAIN diagnosisDiscovery cohortKidney tissueDiagnostic biomarkersAcute interstitial nephritisCXCL9 mRNA expressionAcute kidney injuryBiopsy-confirmed diagnosisAvailable clinical testsNational InstituteKidney injuryTubulointerstitial nephritisInterstitial nephritisKidney biopsyHistological confirmationHistological diagnosisTreatment optionsLymphocyte chemotaxisCXCL9MRNA expression differencesPatientsContrast-Induced Acute Kidney Injury and Cardiovascular Imaging: Danger or Distraction?
Davenport M, Perazella M, Nallamothu B. Contrast-Induced Acute Kidney Injury and Cardiovascular Imaging: Danger or Distraction? Circulation 2023, 147: 847-849. PMID: 36913495, DOI: 10.1161/circulationaha.122.062783.Peer-Reviewed Original ResearchCitationsAltmetricAcquired Disorders of Hypomagnesemia
Rosner M, Ha N, Palmer B, Perazella M. Acquired Disorders of Hypomagnesemia. Mayo Clinic Proceedings 2023, 98: 581-596. PMID: 36872194, DOI: 10.1016/j.mayocp.2022.12.002.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsReduced glomerular filtration rateBody storesBody magnesium storesGlomerular filtration rateSerum magnesium levelsTotal body storesDevelopment of symptomsIntravenous replacementOrgan dysfunctionMagnesium disordersRenal lossMagnesium replacementFiltration rateSevere casesMagnesium storesHypomagnesemiaClinical experienceClinical practiceMagnesium levelsAcquired disordersAmphotericin BMagnesium handlingOptimal managementMedicationsLaboratory assessment
2022
Safety and Adequacy of Kidney Biopsy Procedure in Patients with Obesity
Qian L, Menez S, Hu D, Weinstein J, Melchinger H, Thiessen-Philbrook H, Luciano R, Turner J, Perazella M, Villalobos C, Shaw M, Wilson F, Parikh C, Moledina D. Safety and Adequacy of Kidney Biopsy Procedure in Patients with Obesity. Kidney360 2022, 4: 98-101. PMID: 36700910, PMCID: PMC10101611, DOI: 10.34067/kid.0006602022.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsSafety and Adequacy of Kidney Biopsy Procedure in Patients With Obesity
Qian L, Weinstein J, Melchinger H, Hu D, Menez S, Philbrook H, Luciano R, Perazella M, Shaw M, Parikh C, Wilson F, Moledina D. Safety and Adequacy of Kidney Biopsy Procedure in Patients With Obesity. Journal Of The American Society Of Nephrology 2022, 33: 207-207. DOI: 10.1681/asn.20223311s1207b.Peer-Reviewed Original ResearchImmune checkpoints inhibitors and its link to acute kidney injury and renal prognosis
Kanbay M, Yildiz AB, Siriopol D, Vehbi S, Hasbal NB, Kesgin YE, Celayir M, Selcukbiricik F, Covic A, Perazella MA. Immune checkpoints inhibitors and its link to acute kidney injury and renal prognosis. International Urology And Nephrology 2022, 55: 1025-1032. PMID: 36282399, DOI: 10.1007/s11255-022-03395-y.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAcute kidney injuryImmune checkpoint inhibitorsSolid organ malignanciesCheckpoint inhibitorsKidney injuryOrgan malignanciesNephrotoxic agentsSingle-center retrospective cohort studyType of ICIBaseline serum creatinine levelAcute interstitial nephritisLocation of malignancyRetrospective cohort studySerum creatinine levelsKidney function recoveryRenal replacement therapyUrinary tract obstructionRisk of mortalityICPI treatmentRenal prognosisTract obstructionCohort studyCreatinine levelsFive patientsInterstitial nephritis
Academic Achievements and Community Involvement
activity Director
Meeting Planning and ParticipationAmerican Society of NephrologyDetails07/01/2015 - PresentDescriptionASN Education Co-Director, Board Review Course and Update (BRCU)activity Editor
Journal ServiceItalian Society of NephrologyDetails07/01/2017 - PresentDescriptionCo-Editor-in-Chief for the Journal of Onco-Nephrologyactivity Chair
Meeting Planning and ParticipationNational Kidney FoundationDetails05/01/2019 - PresentDescriptionChair of the NKF Spring Clinical Meeting 2020 (Co-Chair for the meeting in 2019)activity Editor
Journal ServiceAmerican Society of NephrologyDetails07/01/2019 - PresentDescriptionDeputy Editor for ASN journal Kidney360honor Robert G. Narins Lifetime Achievement Award in Education
National AwardAmerican Society of NephrologyDetails07/07/2022United States
Links & Media
News
- December 01, 2023
Dr. Mark Perazella, Internationally Renowned Nephrologist, Retires at Year End
- October 24, 2023
Yale Contributions Shape ASN Kidney Week 2023
- May 25, 2023
YSM PA Online Graduates Celebrated for "Fierce Advocacy"
- May 11, 2023
Discoveries & Impact (May 2023)
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