Chirag Parikh, MD, PhD, FACP

2026

• Spatial analysis reveals cellular microenvironments and mechanisms of inflammation and injury in acute interstitial nephritis

  Baker M, Kakade V, Budiman T, Weiß M, Cunningham J, Sadarangani S, Lerner G, Moeckel G, Rosenberg A, Parikh C, Kluger Y, Moledina D, Cantley L. Spatial analysis reveals cellular microenvironments and mechanisms of inflammation and injury in acute interstitial nephritis. Nature Communications 2026 DOI: 10.1038/s41467-026-77210-y.

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• The Congenital Heart Disease in Children: Kidney-Associated Conditions with Epidemiologic Endpoints (CHICKADEE) study: Study design and protocol

  Greenberg J, Ng D, Sagiv E, Mitsnefes M, Gearhart A, Mulqueen L, Hanken-Arlen O, Gebre H, Boutahri I, Everett A, Flynn J, Parikh C. The Congenital Heart Disease in Children: Kidney-Associated Conditions with Epidemiologic Endpoints (CHICKADEE) study: Study design and protocol. PLOS ONE 2026, 21: e0356639. PMID: 42623390, PMCID: PMC13492810, DOI: 10.1371/journal.pone.0356639.

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• Acute tubular injury versus acute interstitial nephritis in the kidney precision medicine project

  Schaub J, Menon R, Ferreira R, Kiernan E, Schmidt I, Limonte C, Yennapureddy S, Cheng Y, Herlitz L, Rosenberg A, Henderson J, Smith K, Hodgin J, Otto E, Moeckel G, Cantley L, Setty S, Balis U, Demeke D, Fogo A, Bomback A, D’Agati V, Stillman I, Torrealba J, Hendricks A, Bracamonte E, Moreno V, Bhatraju P, Mottl A, Brosius F, Thajudeen B, Coca S, Palevsky P, Randhawa P, Murugan R, Barisoni L, Alpers C, Menez S, Wilson F, Moledina D, Eadon M, Kretzler M, Himmelfarb J, Parikh C, Project T. Acute tubular injury versus acute interstitial nephritis in the kidney precision medicine project. JCI Insight 2026, 11: e204127. PMID: 42579799, PMCID: PMC13464007, DOI: 10.1172/jci.insight.204127.

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• Donor Urinary Biomarkers and the Prediction of Deceased Donor Allograft Function.

  Thiessen Philbrook H, Kerr K, Mohan S, DSouza S, Hu D, Obeid W, Mansour S, Hall I, Doshi M, Reese P, Parikh C. Donor Urinary Biomarkers and the Prediction of Deceased Donor Allograft Function. Journal Of The American Society Of Nephrology 2026 PMID: 42424130, DOI: 10.1681/asn.0000001183.

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• Metabolomic Signatures of Inflammation in Chronic Kidney Disease

  Chen T, Surapaneni A, Estrella M, Appel L, Obeid W, Parikh C, Rooney M, Yu B, Rhee E, Schmidt I, Waikar S, Grams M. Metabolomic Signatures of Inflammation in Chronic Kidney Disease. Kidney Medicine 2026, 8: 101458. PMID: 42668601, PMCID: PMC13524690, DOI: 10.1016/j.xkme.2026.101458.

  Peer-Reviewed Original Research

• Integrating Clinical Decision Support Systems in CKD Management

  Cervantes C, Philbrook H, Bitzel J, Patel D, Menez S, Srialluri N, Sang Y, Scott J, Jaar B, Grams M, Parikh C. Integrating Clinical Decision Support Systems in CKD Management. Kidney International Reports 2026, 11: 106633. PMID: 42436698, PMCID: PMC13355604, DOI: 10.1016/j.ekir.2026.106633.

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• Low cardiac index during periods of arterial hypotension and risk of acute kidney injury in cardiac surgery

  Goeddel L, Koffman L, Zhou X, Hernandez M, Zhao A, Pasrija C, Saha A, Muschelli J, Parikh C, Crainiceanu C, Brown C, Khanna A, Faraday N. Low cardiac index during periods of arterial hypotension and risk of acute kidney injury in cardiac surgery. British Journal Of Anaesthesia 2026 PMID: 42097957, DOI: 10.1016/j.bja.2026.02.037.

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• A MEF2C transcription factor network regulates proliferation of glomerular endothelial cells in diabetic kidney disease

  Ferreira R, Gisch D, Phillips C, Cheng Y, Lucarelli N, Yennapureddy S, Asthana M, Lake B, Bowen W, Fang F, Asghari M, Sabo A, Barwinska D, Ferkowicz M, Toto R, Sedor J, Rosas S, Bjornstad P, Hodgin J, Alpers C, Sarder P, Himmelfarb J, Schaub J, Nair V, Winfree S, Sutton T, Kelly K, Kretzler M, Jain S, El-Achkar T, Dagher P, Eadon M, Adeyi O, Ai L, Narayana S, Alakwaa F, Alexandrov T, Allen J, Alpers C, Alvear A, Ambekar A, Ancheta J, Anderton C, Andre M, Angus S, Anjani K, Annese F, Appelbaum P, Ardayfio J, Arora T, Ascani H, Asghari M, El-Achkar T, Atta M, Atwell T, Aulisio M, Aw S, Azeloglu E, Babaie M, Bagne C, Balderes O, Balis U, Barasch J, Barik M, Barisoni L, Barkmeier A, Barwinska D, Basta J, Bebiak J, Beck L, Berge J, Berglund A, Bernard L, Berry B, Beyda D, Bhanushali J, Bitzer M, Bjornstad P, Blanc V, Blank K, Bledsoe S, Bogen S, Bomback A, Bonevich N, Booth C, Border S, Börner K, Bowen W, Boys C, Bracamonte E, Brosius F, Brown K, Brown L, Bu L, Budiman T, Bueckle A, Bui J, Burg A, Burgess A, Bush L, Bush W, Buth E, Cai Q, Calixte M, Cameron-Wheeler T, Campbell K, Campbell T, Campbell C, Campos B, Canetta P, Cantley L, Caramori M, Carmona-Powell E, Carson J, Chan G, Chan L, Chen J, Chen S, Chen X, Chen Y, cheng T, Cheng Y, Bejarano M, Moaz C, Cimino J, Coca S, Coffman T, Coleman A, Colley M, Collie M, Colona M, Conlon K, Conser N, Cooperman L, Corona-Villalobos C, Crawford D, Creger N, Cuevas-Rios Y, D'Agati V, D'Souza D, Dagher P, de Boer I, de Caestecker M, de Cos M, Gonçalves J, Dekker M, Demeke D, Deng R, Denic A, Derma A, Dighe A, Ding Y, Djambazova K, Donohoe I, Dowd F, Drawz P, Dufresne M, Dull R, Dunn K, Duran D, Eadon M, Eddy S, Elder M, Evo-Ortega L, Fallegger R, Farrow M, Ferkowicz M, Fermin D, Fine D, Flanagan S, Fogo A, Fox M, Frey R, Froment A, Gaba R, Gadegbeku C, Gai L, Gamez G, Gaut J, Gebre K, Gehlenborg N, Gentry A, Geraghty M, Ghag R, Gilliam M, Ginley B, Gisch D, Gordon R, Gorman B, Green M, Greka A, Grewenow S, Gupta R, Gurung B, Guthrie L, Hacohen N, Haddad S, Hall D, Hansen J, Haque Z, Harindhanavudhi T, Hartley J, Hartman J, Hayashi L, Haydak J, He J, He Y, Hedayati S, Henderson D, Henderson J, Hendricks A, Henshaw A, Herlitz L, Hernandez J, Herr B, Himmelfarb J, Hodgin J, Hoofnagle A, Horowitz C, Hsieh E, Huo Y, Huynh C, Iyengar R, Jain S, Janosevic D, Janowczyk A, Jeffers V, Jefferson J, Jefferson N, Jennette J, Johansen C, Jolly S, Jones C, Jones J, Jones K, Joyeux C, Ju W, Kakade V, Kakarla D, Kalil B, Kalva S, Kaspari R, Kaur R, Kaushal M, Keefe N, Keller M, Kelley S, Kellum J, Kelly K, Kelly T, Kent C, Kermani A, Kim T, Kiryluk K, Klett S, Knight R, Knoten A, Koch G, Koewler R, Kovatch P, Kretzler M, Kruse A, Kudva Y, Kukla A, Kuperman M, Kurek C, Küchenhoff L, Asmita L, Lake B, Lardenoije R, Larson A, Larson B, Lash J, Laszik Z, Latt K, Lecker S, Lee D, Lee S, Lee S, Lefferts S, Leite P, Lerman L, Leroux M, Li X, Lienczewski C, Limonte C, Lin J, Liu L, Kovatch P, Livingood D, Lu M, Lucarelli N, Lukowski J, Lum D, Lutnick B, Ma S, Ma S, Madabhushi A, Maikhor S, Maity S, Mandel M, Mansour I, Mao W, Mariani L, Markovic M, Marquez N, Marshall J, McAdams M, McClelland R, McCown P, McGowan M, McMahon G, McMurray A, Mehl K, Meliambro K, Ferreira R, Mendoza K, Menez S, Menon R, Meram E, Meza N, Migas L, Miller C, Miller R, Mimar S, Minor B, Mody P, Moeckel G, Moledina D, Molina-Guzman J, Monroy-Trujillo J, Morales A, Moreno B, Moreno V, Mottl A, Moultrie K, Mukatash T, Munar D, Murugan R, Nachman P, Nadkarni G, Naglah A, Naik A, Nair V, Najafian B, Nam Y, Nanamatsu A, Narasimhan R, Nguyen N, Nwanne G, O'Malley C, O'Toole J, Toro F, Oliver G, Oluwole O, Onul I, Otto E, Palevsky P, Palmer E, Pamreddy A, Parikh C, Parikh S, Park C, Park H, Paša-Tolić L, Patel J, Patel M, Patlis B, Paul A, Pham T, Phuong J, Pillai A, Pinkeney R, Plisiewicz A, Poggio E, Pollack A, Prasad P, Pyle L, Quardokus E, Quinn T, Quiroga A, Rabi S, Ragi N, Randhawa P, Randle T, Rao T, Rao V, Rauchman M, Rauwolf N, Reamy R, Record E, Redmond D, Reinert S, Reis J, Rennke H, Renteria A, Rezaei K, Rhodes R, Ricardo A, Rivera M, Roberts G, Robinson-Cohen C, Rogers E, Rojas-Miguez F, Rosan S, Rosas S, Rose M, Rosen S, Rosenberg A, Rosenberg M, Rosengart M, Rovin B, Roy N, Roy-Chaudhury P, Rubinsky M, Sabo A, Sadusky T, Saez-Rodriguez J, Safadi S, Samari I, Sanora A, Santagata S, Sarder P, Sarkisova N, Sarwal M, Saul J, Saunders M, Schaub J, Schmidt I, Scott R, Scroggins A, Sealfon R, Sedor J, Sendrey D, Sethi M, Sethi S, Setty S, Shah S, Shariff S, Sharma K, Sharma S, Shaw M, Sigdel T, Silva K, Silva P, Sisay E, Smith C, Smith K, Snyder J, Snyder M, Sohail M, Sokolova K, Spates-Harden K, Sperati C, Spraggins J, Srivastava A, Stalbow D, Stashevsky J, Stawicki A, Steck B, Stillman I, Stutzke C, Su J, Subramanian L, Sun J, Rajan S, Sutton T, Taliercio J, Tan R, Tanevski J, Tanious M, b T, Philbrook H, Thurman J, Tokita J, Tommerdahl K, Torrealba J, Toto R, Tout H, Troyanskaya O, Turner J, Tuttle K, Ugwuowo U, Upadhyay A, Ustoyev R, Valerius M, Van de Plas R, Vandyk H, varela G, Vazquez M, Velickovic D, Velickovic M, venkatachalam M, Verdoes A, Verma A, Victoria-Castro A, Vijayan A, Vinovskis C, Vita T, Waikar S, Wang A, Wang B, Wang N, Wang R, Wangperawong A, Ward S, Warfield C, Weins A, Welch J, Wen N, Wen Y, Wightman A, Wilcox A, Williams J, Williams K, Williams M, Wilson F, Winfree S, Winters J, Wofford S, Wolf S, Wong A, Woodhead G, Wright D, Wright Z, Wright Z, Wrobel J, Xu A, Xu S, Yadati P, Yang J, Ye H, Young B, Yu G, Yu S, Zeinoun G, Zeitler E, Zhang B, Zhang G, Zhang K, Zhang S, Zhang Y, Zhou Y. A MEF2C transcription factor network regulates proliferation of glomerular endothelial cells in diabetic kidney disease. Kidney International 2026, 110: 227-244. PMID: 42055320, PMCID: PMC13231425, DOI: 10.1016/j.kint.2026.03.020.

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  MeSH Keywords

• Independent association between acute kidney injury and kidney function trajectory

  Prado V, McCoy I, Zhang Y, Hsu J, Liu K, Muiru A, Chinchilli V, Coca S, Go A, Himmelfarb J, Kaufman J, Kimmel P, Ikizler T, Parikh C, Siew E, Wurfel M, Hsu C. Independent association between acute kidney injury and kidney function trajectory. Kidney International 2026, 110: 206-213. PMID: 42034199, DOI: 10.1016/j.kint.2026.03.013.

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• Development and Validation of Machine Learning Models to Identify Emergency Department Patients at Increased Risk of New or Progressive Acute Kidney Injury

  Hinson J, Zhao X, Ehmann M, Copenhaver M, Shpitser I, Menez S, Parikh C, Strauss A, Kelen G, Badaki-Makun O, Levin S, Klein E. Development and Validation of Machine Learning Models to Identify Emergency Department Patients at Increased Risk of New or Progressive Acute Kidney Injury. Journal Of The American College Of Emergency Physicians Open 2026, 7: 100397. PMID: 42016808, PMCID: PMC13094641, DOI: 10.1016/j.acepjo.2026.100397.

  Peer-Reviewed Original Research