2018
Sex-Specific Outcomes After Transcatheter Aortic Valve Replacement: FDA Patient-Level Meta-Analysis of Premarket Clinical Trials
Zusterzeel R, Mishra NK, Beydoun H, Laschinger J, Wu C, Dong LM, Lin JA, Marinac-Dabic D, Strauss DG, Caños DA. Sex-Specific Outcomes After Transcatheter Aortic Valve Replacement: FDA Patient-Level Meta-Analysis of Premarket Clinical Trials. Journal Of Women's Health 2018, 27: 808-814. PMID: 29741978, DOI: 10.1089/jwh.2017.6760.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementAortic valve replacementClinical trialsPatient-level dataPremarket clinical trialsLower riskMajor bleedingKidney injuryIschemic strokeValve replacementPacemaker implantationMortality riskDichotomous outcomesEfficacy of TAVRInvasive alternative approachPatient-Level MetaLong-term outcomesSex-specific outcomesLower mortality riskRandom-effects modelReintervention riskTAVR armIndividual comorbiditiesPostprocedural complicationsAcute outcomes
2016
Comorbid Parkinson's disease, falls and fractures in the 2010 National Emergency Department Sample
Beydoun HA, Beydoun MA, Mishra NK, Rostant OS, Zonderman AB, Eid SM. Comorbid Parkinson's disease, falls and fractures in the 2010 National Emergency Department Sample. Parkinsonism & Related Disorders 2016, 35: 30-35. PMID: 27887896, PMCID: PMC5663222, DOI: 10.1016/j.parkreldis.2016.11.005.Peer-Reviewed Original ResearchConceptsICD-9-CM codesParkinson's diseaseBone fracturesHospital deathNational Emergency Department SamplePD diagnosisAssociation of PDComorbid Parkinson's diseaseElderly patient visitsEmergency Department SampleFall-related injuriesConfidence intervalsEmergency department settingLogistic regression modelsBone fracture locationPD admissionsU.S. EDsED dischargeElderly patientsED admissionHospitalization lengthFracture prevalenceWorse prognosisMost injuriesDepartment setting
2013
Thrombolysis in Stroke Despite Contraindications or Warnings?
Frank B, Grotta JC, Alexandrov AV, Bluhmki E, Lyden P, Meretoja A, Mishra NK, Shuaib A, Wahlgren NG, Weimar C, Lees KR. Thrombolysis in Stroke Despite Contraindications or Warnings? Stroke 2013, 44: 727-733. PMID: 23391774, DOI: 10.1161/strokeaha.112.674622.Peer-Reviewed Original ResearchConceptsHealth Stroke ScoreAlteplase treatmentStroke ScoreOdds ratioBaseline National InstitutesIntravenous alteplase treatmentPretreatment National InstitutesSingle antiplatelet agentTrial selection criteriaAcute ischemic strokeIschemic stroke patientsProportional odds logistic regression analysisSubgroup of patientsAdjusted odds ratioCommon clinical situationsNational InstituteLogistic regression analysisInternational normalizedIntravenous thrombolysisOral anticoagulationPrior strokeComprehensive retrospective analysisIschemic strokeRankin ScaleUntreated patients