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Markus Müschen, MD, PhD

Arthur H. and Isabel Bunker Professor of Medicine (Hematology) and Professor of Immunobiology; Director, Center of Molecular and Cellular Oncology; Chief, Cellular and Molecular Oncology



Dr. Markus Müschen is the Arthur H. and Isabel Bunker Professor of Hematology, HHMI Faculty Scholar and was appointed Director of the Center of Molecular and Cellular Oncology at Yale in October 2020. He obtained his MD degree in Biochemistry with Helmut Sies (summa cum laude) from the Heinrich-Heine-Universität in Düsseldorf, completed his residency in Hematology-Oncology with Volker Diehl and his MD-PhD with Martin Krönke in Immunology at the University of Cologne, Germany. Since 2009, the Müschen laboratory has established new conceptual frameworks for the understanding of B-cell signaling and energy metabolism and how defects in these mechanisms contribute to autoimmunity and B-cell transformation. Influenced by his postdoctoral training in basic immunology (Klaus Rajewsky and Ralf Küppers) and cancer genetics (Janet D. Rowley), Dr. Müschen is particularly interested in signal transduction pathways that change the clinical trajectory of human B-cell malignancies and B-cell driven autoimmune diseases.

Education & Training

  • Visiting Assistant Professor
    Children's Hospital Los Angeles and University of Southern California (2009)
  • Residency and Fellowship
    University of Cologne (2006)
  • PhD
    Institute for Genetics Cologne, Immunology (2003)
  • Postdoctoral fellowship
    University of Chicago (2002)
  • Postdoctoral fellowship
    Institute for Genetics, University of Cologne (2000)
  • MD
    Heinrich-Heine-Universität Düsseldorf, Biochemistry (1999)

Honors & Recognition

AwardAwarding OrganizationDate
NCI Outstanding Investigator Award 2021National Cancer Institute2021
Elected Member, ASCIAmerican Society of Clinical Investigation2019
18th Annual Maxwell M. Wintrobe Endowed LectureUniversity of Utah2018
Stephen D. Williams, MD, LectureshipIndiana University2018
20th Andrew I. Schafer Distinguished LectureCornell University2018
Norman and Sadie Lee Foundation Endowed ChairNorman and Sadie Lee Foundation2017
NCI Outstanding Investigator Award (R35)National Cancer Institute2016
Howard Hughes Medical Institute Faculty Scholar AwardHoward Hughes Medical Institute2016
Cancer Research UK Programme AwardCancer Research UK2014
Honorary faculty appointmentCambridge University2014
Wellcome Trust Senior Investigator AwardWellcome Trust2013
Sir Alexander Haddow ProfessorshipThe Institute for Cancer Research (ICR)2012
Scholar AwardLeukemia and Lymphoma Society2011
Stand Up To Cancer InnovationAmerican Association for Cancer Research2009
Leukemia Clinical Research AwardGerman Society of Hematology and Oncology2006
Fritz-Melchers-Award in ImmunologyGerman Association of Immunologists2003
Emmy-Noether-AwardGerman Science Foundation (DFG)2002
Irvington Postdoctoral Fellowship AwardCancer Research Institute2000

Professional Service

Scientific Advisory Board, The Blood Research Institute, Milwaukee, WIMember2021 - Present
Hôpital Necker-Enfants Malades Scientific Advisory Board, Hôpital Necker-Enfants MaladesScientific Advisor2018 - Present
NIH Molecular Oncogenesis (MONC) study sectionMember2016 - Present
Biological ChemistryAssociate Editor2009 - Present
Leukemia, Nature Publishing GroupAssociate Editor2008 - 2014

Departments & Organizations