Lisa Leffert, MD
Nicholas Greene Professor of AnesthesiologyCards
Additional Titles
Chair, Anesthesiology
Physician-in-Chief of Anesthesiology , Yale New Haven Hospital and Bridgeport Hospital
Publications Overview
- 126 Publications
- 4,997 Citations
- 1 Yale Co-Author
Administrative Support
Additional Titles
Chair, Anesthesiology
Physician-in-Chief of Anesthesiology , Yale New Haven Hospital and Bridgeport Hospital
Publications Overview
- 126 Publications
- 4,997 Citations
- 1 Yale Co-Author
Administrative Support
Additional Titles
Chair, Anesthesiology
Physician-in-Chief of Anesthesiology , Yale New Haven Hospital and Bridgeport Hospital
Publications Overview
- 126 Publications
- 4,997 Citations
- 1 Yale Co-Author
Administrative Support
About
The Department of Anesthesiology relieves the suffering of those in need through the delivery of safe, effective, and timely anesthesia care, advances the field of anesthesiology through excellence in research, and strives to train the next generation of caregivers.
Titles
Nicholas Greene Professor of Anesthesiology
Chair, Anesthesiology; Physician-in-Chief of Anesthesiology , Yale New Haven Hospital and Bridgeport Hospital
Biography
Dr. Leffert is the Chair of the Yale University School of Medicine and Chief of Anesthesiology at Yale New Haven Hospital and Bridgeport Hospital. Dr. Leffert is nationally and internationally recognized as a clinical expert in obstetric anesthesia and the management of pregnant patients with complex comorbid neurologic and substance use disorders. She recently served as President of the Society for Obstetric Anesthesia & Perinatology (SOAP), reflecting her subspeciality area of concentration. As SOAP President (2019-2020), she led a governance restructure of the Board and its committees to enhance the diversity, inclusion and the quality of its officers and to professionalize their communications and inter-society collaborations and strengthen their ability to execute their mission. Dr. Leffert does research in neurologic disease and vulnerabilities in pregnant women, and has published original research, reviews, and interdisciplinary guidelines on this topic. She lectures on diverse topics such as peripartum stroke, the anesthetic management of patients with intracranial lesions, strategies for placing neuraxial anesthetics in patients with comorbidities, and the peri-delivery care of patients with substance use disorder.
Appointments
Anesthesiology
ChairDualAnesthesiology
ProfessorPrimary
Other Departments & Organizations
Education & Training
- MD
- Harvard Medical School (1991)
Board Certifications
Anesthesiology
- Certification Organization
- AB of Anesthesiology
- Original Certification Date
- 1997
Research
Research at a Glance
Yale Co-Authors
Publications Timeline
Lee Schwamm, MD
Publications
2024
Postdural Puncture Headache: Beyond the Evidence
Berg A, Lucas D, Leffert L. Postdural Puncture Headache: Beyond the Evidence. Best Practice & Research Clinical Anaesthesiology 2024 DOI: 10.1016/j.bpa.2024.11.004.Peer-Reviewed Original ResearchConceptsPostdural puncture headacheCalcitonin gene-related peptideAccidental dural punctureCerebrospinal fluidRelease of calcitonin gene-related peptideManagement of postdural puncture headacheTreat postdural puncture headacheLabor epidural analgesiaGene-related peptideAutonomic nervous systemCerebrospinal fluid dynamicsEvidence-based recommendationsEpidural analgesiaPuncture headacheDural punctureIntrathecal catheterNeuraxial proceduresCSF lossSphenopalatine ganglionAssociated with activationCerebral arteryCerebral vasodilationChronic manifestationsTherapeutic strategiesRoutine useFentanyl in the Labor Epidural Impacts the Results of Intrapartum and Postpartum Maternal and Neonatal Toxicology Tests
Siegel M, Mahowald G, Uljon S, James K, Leffert L, Sullivan M, Hernandez S, Gray J, Schiff D, Bernstein S. Fentanyl in the Labor Epidural Impacts the Results of Intrapartum and Postpartum Maternal and Neonatal Toxicology Tests. Obstetric Anesthesia Digest 2024, 44: 47-48. DOI: 10.1097/01.aoa.0001005456.46508.bf.Peer-Reviewed Original ResearchEvidence-based clinical practice guidelines on postdural puncture headache: infographics
Uppal V, Russell R, Kalagara H, Leffert L, Narouze S. Evidence-based clinical practice guidelines on postdural puncture headache: infographics. Regional Anesthesia & Pain Medicine 2024, 49: 502-504. PMID: 38373816, DOI: 10.1136/rapm-2024-105280.Peer-Reviewed Original ResearchAltmetric
2022
In Response
Pearson ACS, Leffert LR, Kain ZN. In Response. Anesthesia & Analgesia 2022, 135: e3-e4. PMID: 35709456, DOI: 10.1213/ane.0000000000006014.Commentaries, Editorials and LettersBupivacaine Metabolite Can Interfere with Norfentanyl Measurement by LC–MS/MS
Mahowald G, Khaliq T, Basu S, Griggs D, Siegel M, Leffert L, Bernstein S, Flood JG, Uljon S. Bupivacaine Metabolite Can Interfere with Norfentanyl Measurement by LC–MS/MS. The Journal Of Applied Laboratory Medicine 2022, 7: 854-862. PMID: 35259249, DOI: 10.1093/jalm/jfac009.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsThe Society for Obstetric Anesthesia and Perinatology Coronavirus Disease 2019 Registry: An Analysis of Outcomes Among Pregnant Women Delivering During the Initial Severe Acute Respiratory Syndrome Coronavirus-2 Outbreak in the United States
Katz D, Bateman B, Kjaer K, Turner D, Spence N, Habib A, George R, Toledano R, Grant G, Madden H, Butwick A, Lynde G, Minehart R, Beilin Y, Houle T, Sharpe E, Kodali B, Bharadwaj S, Farber M, Palanisamy A, Prabhu M, Gonzales N, Landau R, Leffert L. The Society for Obstetric Anesthesia and Perinatology Coronavirus Disease 2019 Registry: An Analysis of Outcomes Among Pregnant Women Delivering During the Initial Severe Acute Respiratory Syndrome Coronavirus-2 Outbreak in the United States. Obstetric Anesthesia Digest 2022, 42: 27-28. DOI: 10.1097/01.aoa.0000816828.87126.61.Peer-Reviewed Original ResearchCitationsThrombophilias
Toledano R, Leffert L. Thrombophilias. 2022, 313-316. DOI: 10.1007/978-3-030-72487-0_46.Peer-Reviewed Original ResearchHaemophilias
Toledano R, Leffert L. Haemophilias. 2022, 317-321. DOI: 10.1007/978-3-030-72487-0_47.Peer-Reviewed Original ResearchVon Willebrand Disease
Combs D, Leffert L. Von Willebrand Disease. 2022, 323-327. DOI: 10.1007/978-3-030-72487-0_48.Peer-Reviewed Original ResearchLow Molecular Weight Heparin, Unfractionated Heparin and Neuraxial Anaesthesia
Combs D, Leffert L. Low Molecular Weight Heparin, Unfractionated Heparin and Neuraxial Anaesthesia. 2022, 329-335. DOI: 10.1007/978-3-030-72487-0_49.Peer-Reviewed Original Research